Topic
Detection limit
About: Detection limit is a research topic. Over the lifetime, 34379 publications have been published within this topic receiving 644817 citations. The topic is also known as: limit of detection & lower detection limit.
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TL;DR: The utility of these assays was demonstrated in the standardization of nitric oxide-saturated cell culture media, and the release ofNitric oxide by the NONOate compound DEA/NO.
187 citations
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TL;DR: Rec reproducible spectra were obtained for E. coli concentrations as low as approximately 103 cfu/mL for surface-enhanced Raman spectroscopy of aqueous suspensions of bacteria with a suspension of nanocolloidal silver particles.
Abstract: The detection and identification of dilute bacterial samples by surface-enhanced Raman spectroscopy has been explored by mixing aqueous suspensions of bacteria with a suspension of nanocolloidal silver particles. An estimate of the detection limit of E. coli was obtained by varying the concentration of bacteria. By correcting the Raman spectra for the broad librational OH band of water, reproducible spectra were obtained for E. coli concentrations as low as approximately 103 cfu/mL. To aid in the assignment of Raman bands, spectra for E. coli in D2O are also reported.
187 citations
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TL;DR: The practical analytical utility of the differential pulse voltammetry and chronoamperometry method is demonstrated by the measurement of UA in human urine and serum without any preliminary treatment.
Abstract: Electrochemically anodized diamond film electrodes were used for selective detection of uric acid (UA) in the presence of high concentrations of ascorbic acid (AA) by differential pulse voltammetry and chronoamperometry. Because the oxidation peak potential for AA is ∼450 mV more positive than that for UA at anodized diamond electrodes, UA can be determined with very good selectivity. By use of chronoamperometry, linear calibration curves were obtained for UA over the concentration range up to 1 × 10-6 M in 0.1 M HClO4 solution, with the lowest experimental value measured being 5 × 10-8 M. This is consistent with the fact that a statistical analysis of the calibration curve yielded a detection limit of 1.5 × 10-8 M (S/N = 3). AA in less than 20-fold excess does not interfere. The practical analytical utility of the method is demonstrated by the measurement of UA in human urine and serum without any preliminary treatment.
186 citations
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TL;DR: A new homogeneous assay for rapid, highly selective and sensitive detection of Hg(2+) in aqueous solution based on the induced photoluminescence (PL) quenching of BSA-modified gold nanoclusters (BSA-Au NCs), which has excellent selectivity over metal ions and anions.
Abstract: In this paper, we report a new homogeneous assay for rapid, highly selective and sensitive detection of Hg2+ in aqueous solution based on the induced photoluminescence (PL) quenching of BSA-modified gold nanoclusters (BSA-Au NCs). There was a linear correlation between the expression (I0 − I)/I0 and the concentrations of Hg2+ over the ranges of 0.4–43.2 μM, and the corresponding limit of detection (LOD) was 80 nM. The relative standard deviation of 5 replicate measurements was 1.4% for 1.0 × 10−5 mol L−1 Hg2+. Moreover, this method has excellent selectivity over metal ions and anions. The feasibility of the BSA-Au NCs sensor for Hg2+ in different aqueous samples was demonstrated with satisfactory results. Moreover, the possible sensing Hg2+ mechanism was also discussed.
185 citations
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TL;DR: It is easy to operate in HPLC-ICP-MS for mercury species determination since the extracted solution can be directly injected into the HPLC column without pH adjustment and the memory effect of mercury in the ICP-MS measurement system can be reduced.
185 citations