Topic
Detection limit
About: Detection limit is a research topic. Over the lifetime, 34379 publications have been published within this topic receiving 644817 citations. The topic is also known as: limit of detection & lower detection limit.
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TL;DR: In this article, a method for the determination of primary and secondary amino acids is presented, where the reaction of 9-fluorenylmethyl chloroformate with amino acids proceeds under mild conditions in aqueous solution and is complete in 30 sec.
536 citations
TL;DR: Sulfur-doped carbon dots were synthesized using a simple and straightforward hydrothermal method in this article, and as-prepared S-Doped C-dots exhibit significant fluorescence quantum yield (67%) and unique emission behavior.
Abstract: Sulfur-doped carbon dots (S-doped C-dots)were synthesized using a simple and straightforward hydrothermal method. The as-prepared S-doped C-dots exhibit significant fluorescence quantum yield (67%) and unique emission behavior. The spherical S-doped C-dots have an average diameter of 4.6 nm and the fluorescence of S-doped C-dots can be effectively and selectively quenched by Fe3+ ions. Thus, S-doped C-dots were applied as probes toward Fe3+ detection, exhibiting a limit of detection of 0.1 μM.
527 citations
TL;DR: A multi-residue analytical method has been developed and validated for determining a selection of 16 pharmaceuticals: the anti-epileptic carbamazepine, seven analgesic/anti-inflammatory drugs, the analgesic opiate codeine, two antidepressants, beta-blockers, and antibiotic in hospital effluent wastewater samples.
484 citations
TL;DR: The alanine detection limit corresponds to fewer than 6000 molecules injected onto the column and represents an improvement of four orders of magnitude in the state of the art for fluorescent detection of amino acids and an improvement for the detection limit for isothiocyanate derivatives of amino amino acids.
Abstract: Subattomole analysis of fluorescein isothiocyanate (FITC) derivatives of amino acids is accomplished by combining capillary zone electrophoresis for high-efficiency separation with laser-induced fluorescence for high-sensitivity detection. Concentration detection limits range from 5 x 10(-12) molar for alanine to 9 x 10(-11) molar for lysine, injected in the column; 9 x 10(-21) mole of alanine is contained within the approximately 1-nanoliter injection volume at the detection limit. The alanine detection limit corresponds to fewer than 6000 molecules injected onto the column and represents an improvement of four orders of magnitude in the state of the art for fluorescent detection of amino acids and an improvement of six orders of magnitude in the state of the art for the detection limit for isothiocyanate derivatives of amino acids.
470 citations
TL;DR: A highly efficient fluorosensor based on ultrathin graphitic carbon nitride (g-C₃N₄) nanosheets for Cu(2+) was developed and exhibits high selectivity toward Cu( 2+).
Abstract: A highly efficient fluorosensor based on ultrathin graphitic carbon nitride (g-C3N4) nanosheets for Cu2+ was developed. In the absence of metal ions, the nanosheets exhibit high fluorescence; the strong coordination of the Lewis basic sites on them to metal ions, however, causes fluorescence quenching via photoinduced electron transfer leading to the qualitative and semiquantitative detection of metal ions. This fluorosensor exhibits high selectivity toward Cu2+. The whole detection process can be completed within 10 min with a detection limit as low as 0.5 nM. The use of test paper enables the naked-eye detection of Cu2+ with a detection limit of 0.1 nmol. The practical use of this sensor for Cu2+ determination in real water samples was also demonstrated.
445 citations