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Developmental plasticity

About: Developmental plasticity is a research topic. Over the lifetime, 1721 publications have been published within this topic receiving 103438 citations.


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TL;DR: It is demonstrated that developmental plasticity in spectral processing is present at a wide range of neural levels, spanning from photoreceptors to behavior, in fish reared under similar conditions.
Abstract: Developmental plasticity of spectral processing in vertebrates was investigated in fish by using an innate behavior, the optomotor response. Rearing blue acara (Aequidens pulcher; Cichlidae) under white lights of different intensities as well as deprivation of long wavelengths induced significant changes in the animals' responses to chromatic stimuli. Deprivation of short wavelengths had no effect. With this and previous studies on animals reared under similar conditions, we have demonstrated that developmental plasticity in spectral processing is present at a wide range of neural levels, spanning from photoreceptors to behavior. We hypothesize that earlier studies did not reveal such effects because of the rearing and testing conditions used.

52 citations

Journal ArticleDOI
TL;DR: Drosophila can be used to study the developmental mechanisms by which organisms can optimize their behavioral repertoires to enhance their chances for survival and make it possible to introduce 'cultural' and 'social' elements into courtship and mate choice in insects.
Abstract: We demonstrate that Drosophila melanogaster provides a rich model system for studying behavioral development. Two additions to the many well-known advantages of this species are exploited here. First, as in mammals and higher vertebrates, early experience affects behavioral development of Drosophila. Second, the affected behaviors are complex and yet readily studied in the laboratory. Thus, Drosophila can be used to study the developmental mechanisms by which organisms can optimize their behavioral repertoires to enhance their chances for survival. Evidence that early experience affects female responsiveness to courting males is reviewed; in each case, experience modifies responses to behavioral targets. Our results demonstrate that developmental plasticity allows adjustment of intrinsically determined responses to visual targets so that they can take into account the actual characteristics of the developing animal's environment. Furthermore, plasticity makes it possible to introduce 'cultural' and 'social' elements into courtship and mate choice in insects. This previously unrecognized role for developmental plasticity in insects has broad theoretical and practical implications.

52 citations

Journal ArticleDOI
TL;DR: A transient increase in calcineurin activity is found to prevent the shift of responsiveness in the visual cortex following monocular deprivation, and this effect is reversible, implying that the balance between protein kinases and phosphatases is critical for visual cortex plasticity.
Abstract: Numerous protein kinases have been implicated in visual cortex plasticity, but the role of serine/threonine protein phosphatases has not yet been established. Calcineurin, the only known Ca2+/calmodulin-activated protein phosphatase in the brain, has been identified as a molecular constraint on synaptic plasticity in the hippocampus and on memory. Using transgenic mice overexpressing calcineurin inducibly in forebrain neurons, we now provide evidence that calcineurin is also involved in ocular dominance plasticity. A transient increase in calcineurin activity is found to prevent the shift of responsiveness in the visual cortex following monocular deprivation, and this effect is reversible. These results imply that the balance between protein kinases and phosphatases is critical for visual cortex plasticity.

51 citations

Journal ArticleDOI
TL;DR: A number of important outstanding questions remain before the role of GABAergic modulation in long-term plasticity in humans, such as that underpinning recovery after stroke, can be established.

51 citations

Journal ArticleDOI
TL;DR: It is shown that 50 years of climate change have delayed development in high-elevation, season-limited grasshopper populations, but advanced development in populations at lower elevations.
Abstract: Annual species may increase reproduction by increasing adult body size through extended development, but risk being unable to complete development in seasonally limited environments. Synthetic reviews indicate that most, but not all, species have responded to recent climate warming by advancing the seasonal timing of adult emergence or reproduction. Here, we show that 50 years of climate change have delayed development in high-elevation, season-limited grasshopper populations, but advanced development in populations at lower elevations. Developmental delays are most pronounced for early-season species, which might benefit most from delaying development when released from seasonal time constraints. Rearing experiments confirm that population, elevation and temperature interact to determine development time. Population differences in developmental plasticity may account for variability in phenological shifts among adults. An integrated consideration of the full life cycle that considers local adaptation and plasticity may be essential for understanding and predicting responses to climate change.

51 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202316
202244
202172
202076
201953
201864