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Diabetes management

About: Diabetes management is a research topic. Over the lifetime, 6060 publications have been published within this topic receiving 164670 citations.


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Journal ArticleDOI
TL;DR: In this article, the authors discuss clinical studies in which recombinant human hyaluronidase (rHuPH20) was used to increase insulin dispersion and accelerate its absorption.

46 citations

Journal ArticleDOI
TL;DR: Compared to the general Australian population with type 2 diabetes, urban Indigenous Australians with diabetes have greater adjusted risk of albuminuria and PVD but not retinopathy, andUrgent action is required to prevent diabetes at a population level and improve diabetes management in this high-risk population.

46 citations

Journal ArticleDOI
TL;DR: The present sample of AA women from impoverished rural communities exhibited significantly uncontrolled T2DM of long duration with associated obesity and poor lifestyle behaviors, suggesting an innovative CHW led lifestyle intervention may lead to more effective strategies for T2 DM management in this population.

46 citations

Proceedings ArticleDOI
16 Aug 2010
TL;DR: The analysis suggests that individual diabetes patients have a unique way of managing their care through the interpretation of personal health experiences, and calls for a diabetes management system that addresses a patient's physiological, social and psychological activities within the process of individual disease management.
Abstract: The goal of this study was to investigate how diabetes patients use health information to support their daily disease management. A qualitative interview study was conducted with type-2 diabetes patients and healthcare providers. The analysis suggests that individual diabetes patients have a unique way of managing their care through the interpretation of personal health experiences. The ways in which patients learn to interact with their diabetes are detailed in this paper in four themes: understanding typical life routine, accommodating atypical activities, disproving & discovering healthy tips and reevaluating personal expectations. The findings of this study call for a diabetes management system that addresses a patient's physiological, social and psychological activities within the process of individual disease management. The finding opens up new opportunities for designing interactive systems to account for individual differences, encouraging positive patient involvement and sustaining long-term health outcomes.

46 citations

Journal ArticleDOI
TL;DR: It is argued that therapeutic interventions that target glycemia but do not correct the underlying pathogenic disturbances are unlikely to result in a sustained benefit on the disease process and should be replaced with interventions that normalize or at least ameliorate the recognized derangements in physiology.
Abstract: Most treatment guidelines, including those from the American Diabetes Association/European Association for the Study of Diabetes and the International Diabetes Federation, suggest metformin be used as the first-line therapy after diet and exercise. This recommendation is based on the considerable body of evidence that has accumulated over the last 30 years, but it is also supported on clinical grounds based on metformin's affordability and tolerability. As such, metformin is the most commonly used oral antihyperglycemic agent in the U.S. However, based on the release of newer agents over the recent past, some have suggested that the modern approach to disease management should be based upon identification of its etiology and correcting the underlying biological disturbances. That is, we should use interventions that normalize or at least ameliorate the recognized derangements in physiology that drive the clinical manifestation of disease, in this circumstance, hyperglycemia. Thus, it is argued that therapeutic interventions that target glycemia but do not correct the underlying pathogenic disturbances are unlikely to result in a sustained benefit on the disease process. In our field, there is an evolving debate regarding the suggested first step in diabetes management and a call for a new paradigm. Given the current controversy, we provide a Point-Counterpoint debate on this issue. In the point narrative below that precedes the counterpoint narrative, Drs. Abdul-Ghani and DeFronzo provide their argument that a treatment approach for type 2 diabetes based upon correcting the underlying pathophysiological abnormalities responsible for the development of hyperglycemia provides the best therapeutic strategy. Such an approach requires a change in the recommendation for first-line therapy from metformin to a GLP-1 receptor agonist. In the counterpoint narrative that follows Drs. Abdul-Ghani and DeFronzo's contribution, Dr. Inzucchi argues that, based on the medical community's extensive experience and the drug's demonstrated efficacy, safety, low cost, and cardiovascular benefits, metformin should remain the "foundation therapy" for all patients with type 2 diabetes, barring contraindications.-William T. CefaluChief Scientific, Medical & Mission Officer, American Diabetes Association.

46 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023168
2022331
2021480
2020511
2019405
2018386