Topic
Drug carrier
About: Drug carrier is a research topic. Over the lifetime, 18276 publications have been published within this topic receiving 997718 citations. The topic is also known as: drug carriers & drug vehicle.
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TL;DR: In this paper, the authors investigated the key parameters to fabricate PDLLA (Poly( dl -lactic acid)), PDLLGA (poly(dl-lactic-co-glycolic acid) 65 ǫ: 35 and blends of PDLL GA 65 ë:35 and PEG (Poly (ethylene glycol)) microspheres containing bovine serum albumin (BSA) as a model protein using the double-emulsion (water-in-oil-inwater) solvent extraction/evaporation method.
284 citations
TL;DR: The combination of HA with chitosan may afford additional advantages in combining the mucoadhesive potential ofHA with the penetration enhancing effect of chitan, and thereby improve the resultant pharmacokinetic profile.
283 citations
TL;DR: History, all factors affecting niosome formulation, manufacturing conditions, characterization, stability, administration routes and also their comparison with liposome are described.
283 citations
TL;DR: Liposomal drug delivery systems markedly alter the biodistribution of their associated drugs by delaying drug clearance, retarding drug metabolism, decreasing the volume of distribution, and shifting the distribution in favour of diseased tissues with increased capillary permeability.
Abstract: Liposomal drug delivery systems markedly alter the biodistribution of their associated drugs by delaying drug clearance, retarding drug metabolism, decreasing the volume of distribution, and shifting the distribution in favour of diseased tissues with increased capillary permeability. This increases the therapeutic indices of the associated drugs, by increasing the drug concentration in solid tumours and regions of infection, and reducing the drug concentration in normal tissues. Three liposomal formulations have been approved for clinical use.
283 citations
TL;DR: The drug storage/release test indicates that the luminescent SrHAp nanorods show a drug loading and controlled release properties for ibuprofen (IBU), and the emission intensity of Sr HAp in the drug carrier system increases with the cumulative released amount of IBU, making the drug release might be easily tracked and monitored by the change of the luminecence intensity.
282 citations