Topic
Drug carrier
About: Drug carrier is a research topic. Over the lifetime, 18276 publications have been published within this topic receiving 997718 citations. The topic is also known as: drug carriers & drug vehicle.
Papers published on a yearly basis
Papers
More filters
TL;DR: A remarkable improvement in blood circulation of DOX was achieved by use of PEG-PBLA micelle as a carrier presumably due to the reduced reticuloendothelial system uptake of the micelles through a steric stabilization mechanism.
590 citations
TL;DR: This review summarizes the compositional and structural effects of polymers on swelling, loading, and release and approaches to characterize solute release behavior in a dynamic state.
Abstract: Hydrogels have been used by many investigators in controlled-release drug delivery systems because of their good tissue compatibility and easy manipulation of swelling level and, thereby, solute permeability The desired kinetics, duration, and rate of solute release from hydrogels are limited to specific conditions, such as hydrogel properties, amount of incorporated drug, drug solubility, and drug-polymer interactions This review summarizes the compositional and structural effects of polymers on swelling, loading, and release and approaches to characterize solute release behavior in a dynamic state A new approach is introduced to compensate drug effects (solubility and loading) with the release kinetics by varying the structure of heterogeneous polymers Modulated or pulsatile drug delivery using functional hydrogels is a recent trend in hydrogel drug delivery
590 citations
TL;DR: It is suggested that folate targeting constitutes a possible mechanism for improving the specificity of PEG-coated liposomes for cancer cells.
588 citations
TL;DR: The functionalize UCNPs with a polyethylene glycol grafted amphiphilic polymer and conjugating nanoparticles with folic acid, which targets folate receptors over expressed on various types of cancer cells, are demonstrated.
588 citations
TL;DR: In attempt to increase cutaneous drug delivery, microemulsion vehicles have been more and more frequently employed over recent years and a few studies have indicated that the internal structure of microemulsions should allow free diffusion of the drug to optimise cutaneous delivery from these vehicles.
587 citations