Topic
Dysarthria
About: Dysarthria is a research topic. Over the lifetime, 2402 publications have been published within this topic receiving 56554 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: This report reviews 13 cases in which a dysarthria appeared, remitted, and reappeared within seconds, and speculations concerning the origin of the paroxysmal and ataxic character of the Dysarthria are presented along with a preliminary checklist for identifying the disorder.
Abstract: This report reviews 13 cases in which a dysarthria appeared, remitted, and reappeared within seconds. The speech pattern of each case was characteristic of ataxic dysarthria. A cinefluorographic film for one of the subjects provided a rare opportunity to study the articulatory dynamics of this disorder. Multiple sclerosis either was given as a diagnosis or was strongly suspected in each case, and carbamazepine has been an effective treatment. Speculations concerning the origin of the paroxysmal and ataxic character of the dysarthria are presented along with a preliminary checklist for identifying the disorder.
21 citations
TL;DR: Most of the children with classic galactosemia had decreased respiratory-phonatory support for speech, and 33% had disturbed vocal quality that was indicative of cerebellar dysfunction, which were common in children with dysarthria and co-occurred with CAS.
Abstract: Children with classic galactosemia are at risk for motor speech disorders resulting from disruptions in motor planning and programming (childhood apraxia of speech or CAS) or motor execution (dysarthria). In the present study of 33 children with classic galactosemia, 21% were diagnosed with CAS, 3% with ataxic dysarthria, and 3% with mixed CAS-dysarthria. Voice disorders due to laryngeal insufficiency were common in children with dysarthria and co-occurred with CAS. Most (58%) of the children with classic galactosemia had decreased respiratory-phonatory support for speech, and 33% had disturbed vocal quality that was indicative of cerebellar dysfunction. Three children, two diagnosed with CAS and one not diagnosed with a motor speech disorder, had vocal tremors. Treatment of voice dysfunction in neurogenic speech disorders is discussed.
21 citations
TL;DR: This article investigates automatic speech processing approaches dedicated to the detection and localization of abnormal acoustic phenomena in speech signal produced by people with speech disorders and proposes two different approaches that obtain very encouraging results.
Abstract: Perceptual evaluation is still the most common method in clinical practice for diagnosing and following the progression of the condition of people with speech disorders. Although a number of studies have addressed the acoustic analysis of speech productions exhibiting impairments, additional descriptive analysis is required to manage interperson variability, considering speakers with the same condition or across different conditions. In this context, this article investigates automatic speech processing approaches dedicated to the detection and localization of abnormal acoustic phenomena in speech signal produced by people with speech disorders. This automatic process aims at enhancing the manual investigation of human experts while at the same time reducing the extent of their intervention by calling their attention to specific parts of the speech considered as atypical from an acoustical point of view.Two different approaches are proposed in this article. The first approach models only the normal speech, whereas the second models both normal and dysarthric speech. Both approaches are evaluated following two strategies: one consists of a strict phone comparison between a human annotation of abnormal phones and the automatic output, while the other uses a “one-phone delay” for the comparison.The experimental evaluation of both approaches for the task of detecting acoustic anomalies was conducted on two different corpora composed of French dysarthric speakers and control speakers. These approaches obtain very encouraging results and their potential for clinical uses with different types of dysarthria and neurological diseases is quite promising.
21 citations
TL;DR: It is confirmed that SPG15 should be considered in the diagnosis of juvenile atypical parkinsonism, including juvenileonset levodopa-responsive parkinsonistan, and another patient affected with SPG 15 is described.
Abstract: Autosomal recessive hereditary spastic paraplegias with thin corpus callosum (AR HSP-TCC) are rare and complex neurodegenerative disorders characterized by a genetic heterogeneity of which several genes (SPG11 and SPG15, SPG21, SPG47) or loci (SPG32, SPG46) have been identified. In SPG15, additional features have been described [1]: mental retardation, motor neuropathy, dysarthria and pigmentary maculopathy and recently, in a single family with a new homozygous mutation, parkinsonism [2]. In order to further confirm that SPG15 should be considered in the diagnosis of juvenile atypical parkinsonism, we describe another patient affected with SPG15, including juvenileonset levodopa-responsive parkinsonism. A female of Portuguese origin with consanguinity was 17 years old when referred to our center following 12 months of gait difficulties. The patient’s history included mild dysarthria and scholarly delay. Clinical examination demonstrated spastic paraplegia with bilateral extensor plantar reflexes and mild proximal motor deficit in the lower limbs. Vertical saccades were slightly hypometric. By age 19, a left upper limb rest tremor had developed as well as moderate bilateral akinesia, hypertonia, and hypomimia (video). An acute levodopa challenge (250 mg) led to a 60 % improvement of United Parkinson disease rating scale motor score (UPDRSIII) devoted to upper limbs (items 20–25, from 8/24 to 3/24). Rest tremor disappearance was sustained with a levodopa daily dose of M. Anheim and C. Tranchant contributed equally to the work and should be considered as co-last authors.
21 citations
TL;DR: The conclusion is that, in advanced PD, the evaluation of speech characteristics at one moment after levodopa administration is not representative of an entire drug cycle and that an individualized evaluation of an whole drug cycle is warranted before initiation of a speech-language pathology program.
Abstract: Previous research has indicated that in Parkinson's disease (PD) some motor speech characteristics are changed by levodopa administration, while others are not. In advanced PD, the time course of these changes and the correlations with motor performance have not been sufficiently investigated. The purpose was to investigate the sequential changes of respiratory, articulatory, and phonatory speech characteristics across a levodopa drug cycle, using spirometry, acoustic, and motor speech analysis. Seven patients with advanced PD were included. All patients were evaluated sequentually at 15 minute intervals before and following levodopa intake. Data were analysed using repeated measures ANOVA and non-parametric analysis. Significant changes were found in motor function, vital capacity, and standard deviation of the diadochokinetic period. A trend was present for shimmer and frequency of the first formant. Significant inter-individual differences in the sequential changes were demonstrated for nearly all evaluated parameters. The conclusion is that, in advanced PD, the evaluation of speech characteristics at one moment after levodopa administration is not representative of an entire drug cycle and that an individualized evaluation of an entire drug cycle is warranted before initiation of a speech-language pathology program.
21 citations