Topic
Dysarthria
About: Dysarthria is a research topic. Over the lifetime, 2402 publications have been published within this topic receiving 56554 citations.
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TL;DR: The clinical picture of dysarthria-clumsy hand syndrome or ataxic hemiparesis is not specific for lacunar infarction, and the lesion's location is not possible to predict from clinical information alone.
Abstract: We describe two patients, one with clumsy hand-dysarthria syndrome and one with ataxic hemiparesis. Both had pontine lesions on CT. Similar clinical syndromes may be seen with lesions of the internal
8 citations
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TL;DR: A case of pure AOS in setting of an acute stroke is presented to localize more precisely than ever before the brain area responsible for AOS, dorsal premotor cortex (dPMC).
Abstract: Apraxia of speech (AOS) is now recognized as an articulation disorder distinct from dysarthria and aphasia. Various lesions have been associated with AOS in studies that are limited in precise localization due to variability in size and type of pathology. We present a case of pure AOS in setting of an acute stroke to localize more precisely than ever before the brain area responsible for AOS, dorsal premotor cortex (dPMC). The dPMC is in unique position to plan and coordinate speech production by virtue of its connection with nearby motor cortex harboring corticobulbar tract, supplementary motor area, inferior frontal operculum, and temporo-parietal area via the dorsal stream of dual-stream model of speech processing. The role of dPMC is further supported as part of dorsal stream in the dual-stream model of speech processing as well as controller in the hierarchical state feedback control model.
8 citations
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TL;DR: VFS containing several higher frequencies improved both the tremor and axial signs including speech problems in the authors' patient, suggesting that VFS may be of clinical utility in the management of advanced PD.
Abstract: Background and Importance: It is known that subthalamic nucleus deep brain stimulation (STN-DBS) at a fixed high frequency (>100 Hz) improves the primary motor symptoms of Parkinson disease (PD), but this stimulation does not improve or may even exacerbate the later-occurring axial symptoms and signs in PD (e.g., problems with gait or speech). Recent evidence suggests that STN-DBS at a fixed lower frequency (< 100 Hz) can improve speech and gait, but may worsen the tremor in PD. Clinical Presentation: The case involved a female patient who developed severe speech problems after 16 years high-frequency STN-DBS for PD. The tremor and dysarthria symptoms were both effectively treated by applying variable-frequency stimulation (VFS) containing only a combination of high frequencies. Conclusion: VFS containing several higher frequencies improved both the tremor and axial signs including speech problems in our patient. This case report suggests that VFS may be of clinical utility in the management of advanced PD, but this should be further verified in larger well-controlled studies.
8 citations
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TL;DR: LFS compared to no stimulation and HFS, in the absence of l-dopa effect, significantly improved DDK and speech intelligibility for sentence, among patients with severe speech impairment, and may offer both an immediate and long-lasting improvement of speech.
8 citations
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TL;DR: In this article, the prevalence of motor speech disorders (MSDs) in non-fluent primary progressive aphasia (nfvPPA) was investigated in a large sample of German-speaking patients with different types of PPA.
8 citations