Topic
Dysarthria
About: Dysarthria is a research topic. Over the lifetime, 2402 publications have been published within this topic receiving 56554 citations.
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TL;DR: In this article, the authors proposed a novel approach where the intelligibility is estimated as the percentage of correct words uttered by a speaker with dysarthria by matching and verifying utterances of the speaker with disarthria against control speakers' utterances in phone posterior feature space and broad phonetic posterior space.
Abstract: In the literature, the task of dysarthric speech intelligibility assessment has been approached through development of different low-level feature representations, subspace modeling, phone confidence estimation or measurement of automatic speech recognition system accuracy. This paper proposes a novel approach where the intelligibility is estimated as the percentage of correct words uttered by a speaker with dysarthria by matching and verifying utterances of the speaker with dysarthria against control speakers’ utterances in phone posterior feature space and broad phonetic posterior feature space. Experimental validation of the proposed approach on the UA-Speech database, with posterior feature estimators trained on the data from auxiliary domain and language, obtained a best Pearson's correlation coefficient ( $r$ ) of 0.950 and Spearman's correlation coefficient ( $\rho$ ) of 0.957. Furthermore, replacing control speakers’ speech with speech synthesized by a neural text-to-speech system obtained a best $r$ of 0.931 and $\rho$ of 0.961.
5 citations
TL;DR: 嚥下障害を合併したdysarthria1例に対して害モデルを基盤とした, £1,000,000-£2,500,000 €3,000 ˬ4,000 (£3,500-5,000) ersatz world record for sales in a year.
Abstract: 嚥下障害を合併したdysarthria1例に対して臨床的マネージメントを行った.治療プランの立案においては, 嚥下と発話の動作を比較し神経生理学的および解剖学的関連性と相違に着目し, 障害モデルを基盤とした.その結果, 嚥下と発話の機能は平行して著明に改善し, 嚥下障害の重症度は6段階評価尺度でレベル1から5へ, 単語明瞭度は18.5%から89.1%となった.今回の結果から嚥下障害を合併したdysarthria例に対しては, 嚥下と発話の神経生理学的および解剖学的関連性と相違に着目することによって機能障害および能力障害レベルの治療プランが明確化し効率的な治療結果を両者に同時に得ることが可能であると示唆された.また, 嚥下障害のマネージメントにおいては, チーム・アプローチの重要性が示された.
5 citations
TL;DR: Wang et al. as discussed by the authors reported a novel splicing mutation in the SLC16A2 gene in an 18-month-old male patient with allan-herndon-dudley syndrome.
Abstract: Allan-Herndon-Dudley syndrome (AHDS) is an X-linked recessive neurodegenerative disorder caused by mutations in the SLC16A2 gene that encodes thyroid hormone transporter. AHDS has been rarely reported in China.This study reported a novel splicing mutation in the SLC16A2 gene in an 18-month-old male patient with AHDS. The patient was born to non-consanguineous, healthy parents of Chinese origin. He passed new-born screening for hypothyroidism, but failed to reach developmental milestones. He presented with hypotonia, severe mental retardation, dysarthria and ataxia. Genetic analysis identified a novel splicing mutation, NM_006517.4: c.431-2 A > G, in the SLC16A2 gene inherited from his mother. The patient received Triac treatment, (triiodothyroacetic acid), a thyroid hormone analogue for 3 months. Triac treatment effectively reduced serum TSH concentrations and normalized serum T3 concentrations in the patient.This study reported the first case of AHDS treated by Triac in China. And the study expanded the mutational spectrum of the SLC16A2 gene in AHDS patients.
5 citations
TL;DR: This is the first study to examine ataxic dysarthria in a sign language user, and it is novel that the limbs are employed for both linguistic and non-linguistic movements.
Abstract: Speech and sign production both require precise coordination of multiple articulators. The characteristics of dysarthria following ataxia have been well-documented, but less is known about the consequences of ataxia for sign language, which uses the hands and arms as articulators. This is the first study to examine ataxic dysarthria in a sign language user. What is novel in this research is that the limbs are employed for both linguistic and non-linguistic movements. Notably, sign production deficits broadly resembled ataxic dysarthria, while non-linguistic movement deficits were similar to those previously reported for ataxic limb movement.
5 citations
Journal Article•
TL;DR: A case study of 26 year old male patient who was diagnosed as flaccid dysarthria due to delayed anoxic encephalopathy by attempting suicide through hanging concluded the importance of counseling and family centered approach regarding speech therapy outcome and alternative and augmentative communication (AAC).
Abstract: . Present study highlights a case of 26 year old male patient who was diagnosed as flaccid dysarthria due to delayed anoxic encephalopathy by attempting suicide through hanging. Assessment and management based on speech therapy has been emancipated. This case study concluded the importance of counseling and family centered approach regarding speech therapy outcome and alternative and augmentative communication (AAC). However, patient preferred verbal mode of communication and his lack of motivation failed the use of AAC with him. A composite therapy approach including traditional approaches, prosody and naturalness, increasing respiratory support along with visual biofeedback were used, which did not turned out to be effective. This dilemma to either direct therapy for verbal mode of communication which is not effective for the case or to use AAC needs further thinking and studies with more participants to find an appropriate solution which could lead us out of this impasse to some direction. Thus the challenge for speech therapists exists. Key words: Encephalopathy, anoxic encephalopathy, dysarthria, hyperkinetic dysarthria, flaccid dysarthria, hanging, suicidal attempt
4 citations