Topic
Dysarthria
About: Dysarthria is a research topic. Over the lifetime, 2402 publications have been published within this topic receiving 56554 citations.
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11 Sep 2018
TL;DR: A recently developed method to extract phonological features from speech signals based on the Sound Patterns of English phonological model is used, which could be helpful to assess new specific speech aspects such as the movement of different articulators involved in the speech production process.
Abstract: Speech disorders are common symptoms among Parkinson’s disease patients and affect the speech of patients in different aspects Currently, there are few studies that consider the phonological dimension of Parkinson’s speech In this work, we use a recently developed method to extract phonological features from speech signals These features are based on the Sound Patterns of English phonological model The extraction is performed using pre-trained Deep Neural Networks to infer the probabilities of phonological features from short-time acoustic features An i-vector extractor is trained with the phonological features The extracted i-vectors are used to classify patients and healthy speakers and assess their neurological state and dysarthria level This approach could be helpful to assess new specific speech aspects such as the movement of different articulators involved in the speech production process
3 citations
01 Apr 2013
TL;DR: A 27-year-old woman was transferred to the authors' hospital for further evaluation of progressive gait difficulty, slurred speech, right hand tremor, and temporal lobe lesion and a small area of increased signal on fluid-attenuated inversion recovery (FLAIR) sequence in the right temporal lobe was shown.
Abstract: A 27-year-old woman was transferred to our hospital for further evaluation of progressive gait difficulty, slurred speech, right hand tremor, and temporal lobe lesion. She was in her usual state of good health until 1 year earlier when she developed right hand weakness and tremor and slurred speech. Her symptoms gradually worsened over the next 6 months and significant dysarthria and right hand weakness and intention tremor was noted. Her penmanship was illegible, tandem gait was impaired, and rapid alternating movements with the right hand were slow compared to the left. A dilated left pupil was diagnosed as an Adie tonic pupil. MRI showed a small area of increased signal on fluid-attenuated inversion recovery (FLAIR) sequence in the right temporal lobe. She was readmitted because of falls, progressive cognitive impairment, gait ataxia, dysarthria, and right hand tremor. On gait testing, she could only walk with the assistance of 2 aides. Because of increased size of the right temporal lobe lesion on repeat MRI, she was transferred to our hospital for consideration of brain biopsy.
3 citations
TL;DR: The impact of DBS on voice and speech quality significantly varies between studies, and the stimulated anatomical region may have a significant role since the stimulation of the pallidal area was mainly associated with voice quality improvement, in contrast with other regions.
Abstract: OBJECTIVE
Deep brain stimulation (DBS) has considerable efficacy for the motor dysfunction of idiopathic Parkinson's disease (PD) on patient quality of life. However, the benefit of DBS on voice and speech quality remains controversial. We carried out a systematic review to understand the influence of DBS on parkinsonian dysphonia and dysarthria.
DATA SOURCES
A PubMed/MEDLINE and Cochrane systematic review was carried out following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Population, Intervention, Comparison, Outcome, Timing, and Setting (PICOTS) statements.
REVIEW METHODS
Three investigators screened studies published in the literature from inception to May 2022. The following data were retrieved: age, demographic, sex, disease duration, DBS duration, DBS location, speech, and voice quality measurements.
RESULTS
From the 180 studies identified, 44 publications met the inclusion criteria, accounting for 866 patients. Twenty-nine studies focused on voice/speech quality in subthalamic DBS patients, and 6 included patients with stimulation of pallidal, thalamic, and zona incerta regions. Most studies (4/6) reported a deterioration of the vocal parameters on subjective voice quality evaluation. For speech, the findings were more contrasted. There was an important heterogeneity between studies regarding the voice and speech quality outcomes used to evaluate the impact of DBS on voice/speech quality.
CONCLUSION
The impact of DBS on voice and speech quality significantly varies between studies. The stimulated anatomical region may have a significant role since the stimulation of the pallidal area was mainly associated with voice quality improvement, in contrast with other regions. Future controlled studies comparing all region stimulation are needed to get reliable findings.
LEVEL OF EVIDENCE
Level III: evidence from evidence summaries developed from systematic reviews.
3 citations
TL;DR: In both normal and PD speech, consonants had more features identified when they belonged to content words, word-initial syllables or final-phrase syllables, suggesting that in Parkinson's disease speech disorders relate to motor control and not to a loss of the linguistic knowledge.
Abstract: We examined the effect of linguistic factors on the perceptual identification of intervocalic consonants produced by speakers with Parkinson's Diseases (PD). To neutralize the effect of preceding and following contexts, all the intervocalic consonants were excised with half the preceding and following vowels.We recorded 10 PD and 10 healthy speakers reading a text. An average of 114 VCV sequences per speaker was obtained. In total, our corpus consisted of 2280 stimuli. For the perception test, 20 adults native speakers of French were instructed that they would be presented utterances produced by different speakers and that they were to identify the sequences and write what they heard. No information was given on the sequence type (VCV).The reported consonant was examined in relation to the intended consonant; the score of distorsion was the number of phonetic features differing from the prototypical consonant. The results were examined as a function of the following/or preceding linguistic factors: consonant nature, oral/nasal vocalic context, class of word (function or content) and prosodic position within sentences.Consonant imprecision was confirmed in the speech of PD speakers. Two groups of patients were observed: the former with a low degree of dysarthria severity and scores of consonant identification close to that of healthy speakers; the latter with a high degree of dysarthria severity and a low identification score.Linguistic factors were shown to affect consonant production and perception. In both normal and PD speech, consonants had more features identified when they belonged to content words, word-initial syllables or final-phrase syllables. This suggests that in Parkinson's disease speech disorders relate to motor control and not to a loss of the linguistic knowledge.
3 citations
3 citations