Topic
Dysarthria
About: Dysarthria is a research topic. Over the lifetime, 2402 publications have been published within this topic receiving 56554 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: Using an optoelectronic device, lower lip trajectories during production of sentence utterances in patients with Parkinson's disease, Huntington's disease (HD), cerebellar atrophy (CA), and pseudobulbar palsy (PB) are recorded.
Abstract: The various components of the central motor system are expected to play a similar role in speech production and in upper limb control. Slowed articulatory performance, therefore, must be expected in disorders of the corticobulbar tracts, cerebellum, and basal ganglia. Using an optoelectronic device, the present study recorded lower lip trajectories during production of sentence utterances in patients with Parkinson's disease (PD), Huntington's disease (HD), cerebellar atrophy (CA), and pseudobulbar palsy (PB). The various subject groups showed a similar range of overall motor disability. Patients with CA and PB exhibited slowed movement execution in terms of a reduced ratio of peak velocity to maximum amplitude ("stiffness"). In contrast to upper limb motor control, the lip excursions showed an uncompromised shape of velocity profiles. Two different patterns emerged in HD. A single patient suffering from the akinetic-rigid Westphal variant of this disease had articulatory hypometria, whereas the remaining subjects showed significant bradykinesia under increased temporal demands, concomitant with normal movement amplitudes. The PD patients had unimpaired velocity-displacement relationships. Presumably, biomechanical constraints such as the rather small excursions of articulatory lower lip gestures or the scarce spindle supply of facial muscles account for the observed discrepancies between upper limb and speech motor control in PD.
67 citations
TL;DR: The speech of individuals carrying the mutant HTT gene is a behavioural/motor/cognitive marker demonstrating some potential as an objective indicator of early HD onset and disease progression, and changes in speech production appear to be developing prior to diagnosis.
67 citations
TL;DR: The phoneme intelligibility scores of dysarthric speakers obtained by the three investigated intelligibility model types are reliable and the intelligibility scoring system is now ready to be implemented in a clinical tool.
Abstract: Background: Currently, clinicians mainly rely on perceptual judgements to assess intelligibility of dysarthric speech. Although often highly reliable, this procedure is subjective with a lot of intrinsic variables. Therefore, certain benefits can be expected from a speech technology‐based intelligibility assessment. Previous attempts to develop an automated intelligibility assessment mainly relied on automatic speech recognition (ASR) systems that were trained to recognize the speech of persons without known impairments. In this paper automatic speech alignment (ASA) systems are used instead. In addition, previous attempts only made use of phonemic features (PMF). However, since articulation is an important contributing factor to intelligibility of dysarthric speech and since phonological features (PLF) are shared by multiple phonemes, phonological features may be more appropriate to characterize and identify dysarthric phonemes.Aims: To investigate the reliability of objective phoneme intelligibility sco...
67 citations
TL;DR: In this article, the authors provided a computational system model of effective connectivity in the human brain underlying overt speech production, which revealed a core network consisting of Brodmann's area (BA) 44 in Broca's region, anterior insula, basal ganglia, cerebellum, premotor cortex (PMC, BA 6), and primary motor cortex (M1, areas 4a/4p).
67 citations
TL;DR: The results suggest that simple alterations of speech signals do not explain the differences in intelligibility that have been observed when parkinsonian dysarthric speakers reduce speaking rates.
Abstract: The effect of two types of temporal alterations, paced and synthetic, on the intelligibility of parkinsonian dysarthric speech was investigated. Six speakers with idiopathic Parkinson’s disease ser...
67 citations