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Showing papers on "Energy source published in 2016"


Journal ArticleDOI
TL;DR: In this article, the hydrogen (H2) and oxygen (O2) fuel cell is the one with zero carbon emission and water as the only byproduct, which is essential to ensure higher life cycle and less decay in cell efficiency.
Abstract: Increasing demand for finding eco-friendly and everlasting energy sources is now totally depending on fuel cell technology. Though it is an eco-friendly way of producing energy for the urgent requirements, it needs to be improved to make it cheaper and more eco-friendly. Although there are several types of fuel cells, the hydrogen (H2) and oxygen (O2) fuel cell is the one with zero carbon emission and water as the only byproduct. However, supplying fuels in the purest form (at least the H2) is essential to ensure higher life cycles and less decay in cell efficiency. The current large-scale H2 production is largely dependent on steam reforming of fossil fuels, which generates CO2 along with H2 and the source of which is going to be depleted. As an alternate, electrolysis of water has been given greater attention than the steam reforming. The reasons are as follows: the very high purity of the H2 produced, the abundant source, no need for high-temperature, high-pressure reactors, and so on. In earlier days,...

1,757 citations


Journal ArticleDOI
TL;DR: Short chain fatty acids have distinct physiological effects: they contribute to shaping the gut environment, influence the physiology of the colon, they can be used as energy sources by host cells and the intestinal microbiota and they also participate in different host-signaling mechanisms.
Abstract: The colon is inhabited by a dense population of microorganisms, the so-called “gut microbiota”, able to ferment carbohydrates and proteins that escape absorption in the small intestine during digestion. This microbiota produces a wide range of metabolites, including short chain fatty acids (SCFA). These compounds are absorbed in the large bowel and are defined as 1-6 carbon volatile fatty acids which can present straight or branched-chain conformation. Their production is influenced by the pattern of food intake and diet-mediated changes in the gut microbiota. SCFA have distinct physiological effects: they contribute to shaping the gut environment, influence the physiology of the colon, they can be used as energy sources by host cells and the intestinal microbiota and they also participate in different host-signalling mechanisms. We summarize the current knowledge about the production of SCFA, including bacterial cross-feedings interactions, and the biological properties of these metabolites with impact on the human health

1,344 citations


Journal ArticleDOI
TL;DR: In this article, the pyrolysis process for each type of plastics and the main process parameters that influenced the final end product such as oil, gaseous and char were reviewed.

1,150 citations


Journal ArticleDOI
TL;DR: This Review focuses on methods developed to synthesize polymers derived from lignin, monolignols, and lignIn-derived chemicals, such as vanillin.
Abstract: The majority of commodity plastics and materials are derived from petroleum-based chemicals, illustrating the strong dependence on products derived from non-renewable energy sources. As the most accessible, renewable form of carbon (in comparison to CO2), lignocellulosic biomass (defined as organic matter available on a renewable basis) has been acknowledged as the most logical carbon-based feedstock for a variety of materials such as biofuels and chemicals. This Review focuses on methods developed to synthesize polymers derived from lignin, monolignols, and lignin-derived chemicals. Major topics include the structure and processing of lignocellulosic biomass to lignin, polymers utilizing lignin as a macromonomer, synthesis of monomers and polymers from monolignols, and polymers from lignin-derived chemicals, such as vanillin.

1,008 citations


Journal ArticleDOI
TL;DR: It has been shown that the butyrogenic effects of ITF and AXOS are the result of cross-feeding interactions between bifidobacteria and butyrate-producing colon bacteria, such as Faecalibacterium prausnitzii and Anaerostipes, Eubacterium, and Roseburia species (clostridial cluster XIVa).
Abstract: With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the human gastrointestinal tract, prebiotics such as inulin-type fructans (ITF) and arabinoxylan-oligosaccharides (AXOS) can be consumed to increase the number of bifidobacteria in the colon. Several functions have been attributed to bifidobacteria, encompassing degradation of non-digestible carbohydrates, protection against pathogens, production of vitamin B, antioxidants, and conjugated linoleic acids, and stimulation of the immune system. During life, the numbers of bifidobacteria decrease from up to 90% of the total colon microbiota in vaginally delivered breast-fed infants to <5% in the colon of adults and they decrease even more in that of elderly as well as in patients with certain disorders such as antibiotic-associated diarrhea, inflammatory bowel disease, irritable bowel syndrome, obesity, allergies, and regressive autism. It has been suggested that the bifidogenic effects of ITF and AXOS are the result of strain-specific yet complementary carbohydrate degradation mechanisms within cooperating bifidobacterial consortia. Except for a bifidogenic effect, ITF and AXOS also have shown to cause a butyrogenic effect in the human colon, i.e., an enhancement of colon butyrate production. Butyrate is an essential metabolite in the human colon, as it is the preferred energy source for the colon epithelial cells, contributes to the maintenance of the gut barrier functions, and has immunomodulatory and anti-inflammatory properties. It has been shown that the butyrogenic effects of ITF and AXOS are the result of cross-feeding interactions between bifidobacteria and butyrate-producing colon bacteria, such as Faecalibacterium prausnitzii (clostridial cluster IV) and Anaerostipes, Eubacterium, and Roseburia species (clostridial cluster XIVa). These kinds of interactions possibly favor the co-existence of bifidobacterial strains with other bifidobacteria and with butyrate-producing colon bacteria in the human colon.

1,004 citations


Journal ArticleDOI
TL;DR: In this paper, the effect of pyrolysis process parameters on the production of biochar through biochar of biomass is discussed and a comparison between the existing techniques is established in the present work.
Abstract: Biomass is considered to have potential to be used as an alternative energy source. High carbon content present in biomass converts it into high energy biochar on thermochemical treatment. Among few well established thermochemical technologies for the treatment of biomass and biogenic waste to produce high energy char along with oil and gaseous yield, pyrolysis is the most studied and discussed technique in the recent past. A comparison between the existing techniques is established in the present work. Production of char from the biomass and biogenic wastes is reviewed and it was found that yield of the biochar depends upon the biomass composition like moisture content and presence of cellulose or lignin. Pyrolysis product distribution and their quality strongly depend upon the process parameters. Different biomasses which can be used as raw material in pyrolysis are also reviewed and categorized depending upon their source. Pyrolysis process parameters such as temperature, heating rate, residence time etc. also influence the biochar yield. This study discusses the effect of these process parameters on the production of biochar through pyrolysis of biomass.

944 citations


Journal ArticleDOI
TL;DR: The need of solar industry with its fundamental concepts, worlds energy scenario, highlights of researches done to upgrade solar industry, its potential applications and barriers for better solar industry in future in order to resolve energy crisis as mentioned in this paper.
Abstract: World׳s energy demand is growing fast because of population explosion and technological advancements. It is therefore important to go for reliable, cost effective and everlasting renewable energy source for energy demand arising in future. Solar energy, among other renewable sources of energy, is a promising and freely available energy source for managing long term issues in energy crisis. Solar industry is developing steadily all over the world because of the high demand for energy while major energy source, fossil fuel, is limited and other sources are expensive. It has become a tool to develop economic status of developing countries and to sustain the lives of many underprivileged people as it is now cost effective after a long aggressive researches done to expedite its development. The solar industry would definitely be a best option for future energy demand since it is superior in terms of availability, cost effectiveness, accessibility, capacity and efficiency compared to other renewable energy sources. This paper therefore discusses about the need of solar industry with its fundamental concepts, worlds energy scenario, highlights of researches done to upgrade solar industry, its potential applications and barriers for better solar industry in future in order to resolve energy crisis.

894 citations


Journal ArticleDOI
TL;DR: The mechanisms behind microbial metabolite effects, which could be modified by diet to achieve the objective of preventing colorectal cancer in Western societies are discussed.
Abstract: Colorectal cancer is one of the so-called westernized diseases and the second leading cause of cancer death worldwide. On the basis of global epidemiological and scientific studies, evidence suggests that the risk of colorectal cancer is increased by processed and unprocessed meat consumption but suppressed by fibre, and that food composition affects colonic health and cancer risk via its effects on colonic microbial metabolism. The gut microbiota can ferment complex dietary residues that are resistant to digestion by enteric enzymes. This process provides energy for the microbiota but culminates in the release of short-chain fatty acids including butyrate, which are utilized for the metabolic needs of the colon and the body. Butyrate has a remarkable array of colonic health-promoting and antineoplastic properties: it is the preferred energy source for colonocytes, it maintains mucosal integrity and it suppresses inflammation and carcinogenesis through effects on immunity, gene expression and epigenetic modulation. Protein residues and fat-stimulated bile acids are also metabolized by the microbiota to inflammatory and/or carcinogenic metabolites, which increase the risk of neoplastic progression. This Review will discuss the mechanisms behind these microbial metabolite effects, which could be modified by diet to achieve the objective of preventing colorectal cancer in Western societies.

672 citations


Journal ArticleDOI
TL;DR: In this paper, a comparison between photoelectrochemical (PEC) and photovoltaic-electrolytic (PV-E) solar-hydrogen production of 3.65 kilotons H2 per year was performed to assess the economics of each technology, and to provide a basis for comparison within the broader energy landscape.
Abstract: A technoeconomic analysis of photoelectrochemical (PEC) and photovoltaic-electrolytic (PV-E) solar-hydrogen production of 10000 kg H2 day−1 (3.65 kilotons per year) was performed to assess the economics of each technology, and to provide a basis for comparison between these technologies as well as within the broader energy landscape. Two PEC systems, differentiated primarily by the extent of solar concentration (unconcentrated and 10× concentrated) and two PV-E systems, differentiated by the degree of grid connectivity (unconnected and grid supplemented), were analyzed. In each case, a base-case system that used established designs and materials was compared to prospective systems that might be envisioned and developed in the future with the goal of achieving substantially lower overall system costs. With identical overall plant efficiencies of 9.8%, the unconcentrated PEC and non-grid connected PV-E system base-case capital expenses for the rated capacity of 3.65 kilotons H2 per year were $205 MM ($293 per m2 of solar collection area (mS−2), $14.7 WH2,P−1) and $260 MM ($371 mS−2, $18.8 WH2,P−1), respectively. The untaxed, plant-gate levelized costs for the hydrogen product (LCH) were $11.4 kg−1 and $12.1 kg−1 for the base-case PEC and PV-E systems, respectively. The 10× concentrated PEC base-case system capital cost was $160 MM ($428 mS−2, $11.5 WH2,P−1) and for an efficiency of 20% the LCH was $9.2 kg−1. Likewise, the grid supplemented base-case PV-E system capital cost was $66 MM ($441 mS−2, $11.5 WH2,P−1), and with solar-to-hydrogen and grid electrolysis system efficiencies of 9.8% and 61%, respectively, the LCH was $6.1 kg−1. As a benchmark, a proton-exchange membrane (PEM) based grid-connected electrolysis system was analyzed. Assuming a system efficiency of 61% and a grid electricity cost of $0.07 kWh−1, the LCH was $5.5 kg−1. A sensitivity analysis indicated that, relative to the base-case, increases in the system efficiency could effect the greatest cost reductions for all systems, due to the areal dependencies of many of the components. The balance-of-systems (BoS) costs were the largest factor in differentiating the PEC and PV-E systems. No single or combination of technical advancements based on currently demonstrated technology can provide sufficient cost reductions to allow solar hydrogen to directly compete on a levelized cost basis with hydrogen produced from fossil energy. Specifically, a cost of CO2 greater than ∼$800 (ton CO2)−1 was estimated to be necessary for base-case PEC hydrogen to reach price parity with hydrogen derived from steam reforming of methane priced at $12 GJ−1 ($1.39 (kg H2)−1). A comparison with low CO2 and CO2-neutral energy sources indicated that base-case PEC hydrogen is not currently cost-competitive with electrolysis using electricity supplied by nuclear power or from fossil-fuels in conjunction with carbon capture and storage. Solar electricity production and storage using either batteries or PEC hydrogen technologies are currently an order of magnitude greater in cost than electricity prices with no clear advantage to either battery or hydrogen storage as of yet. Significant advances in PEC technology performance and system cost reductions are necessary to enable cost-effective PEC-derived solar hydrogen for use in scalable grid-storage applications as well as for use as a chemical feedstock precursor to CO2-neutral high energy-density transportation fuels. Hence such applications are an opportunity for foundational research to contribute to the development of disruptive approaches to solar fuels generation systems that can offer higher performance at much lower cost than is provided by current embodiments of solar fuels generators. Efforts to directly reduce CO2 photoelectrochemically or electrochemically could potentially produce products with higher value than hydrogen, but many, as yet unmet, challenges include catalytic efficiency and selectivity, and CO2 mass transport rates and feedstock cost. Major breakthroughs are required to obtain viable economic costs for solar hydrogen production, but the barriers to achieve cost-competitiveness with existing large-scale thermochemical processes for CO2 reduction are even greater.

604 citations


Journal ArticleDOI
TL;DR: In this paper, the authors present a comprehensive review of various aspects of hybrid renewable energy system (HRES) including prefeasibility analysis, optimum sizing, modeling, control aspects and reliability issues.
Abstract: The demand for electricity is increasing day by day, which cannot be fulfilled by non-renewable energy sources alone. Renewable energy sources such as solar and wind are omnipresent and environmental friendly. The renewable emulnergy sources are emerging options to fulfill the energy demand, but unreliable due to the stochastic nature of their occurrence. Hybrid renewable energy system (HRES) combines two or more renewable energy sources like wind turbine and solar system. The objective of this paper is to present a comprehensive review of various aspects of HRES. This paper discusses prefeasibility analysis, optimum sizing, modeling, control aspects and reliability issues. The application of evolutionary technique and game theory in hybrid renewable energy is also presented in this paper.

573 citations


Journal ArticleDOI
TL;DR: An overview of the past and recent developments in energy harvesting communications and networking is presented and a number of possible future research avenues are highlighted.
Abstract: Recent emphasis on green communications has generated great interest in the investigations of energy harvesting communications and networking. Energy harvesting from ambient energy sources can potentially reduce the dependence on the supply of grid or battery energy, providing many attractive benefits to the environment and deployment. However, unlike the conventional stable energy, the intermittent and random nature of the renewable energy makes it challenging in the realization of energy harvesting transmission schemes. Extensive research studies have been carried out in recent years to address this inherent challenge from several aspects: energy sources and models, energy harvesting and usage protocols, energy scheduling and optimization, implementation of energy harvesting in cooperative, cognitive radio, multiuser and cellular networks, etc. However, there has not been a comprehensive survey to lay out the complete picture of recent advances and future directions. To fill such a gap, in this paper, we present an overview of the past and recent developments in these areas and highlight a number of possible future research avenues.

Journal ArticleDOI
TL;DR: A critical review of the literature on butyrate and its effects on multiple aspects of host physiology with a focus on brain function and behaviour is provided and it is hypothesised that butyrates and other volatile SCFAs produced by microbes may be involved in regulating the impact of the microbiome on behaviour including social communication.

Journal ArticleDOI
TL;DR: In this article, the effect of dopant type, ionic size and its concentration on the crystal structure, electronic property and morphology of doped ZnO with a narrower band gap is reviewed systematically.

Journal ArticleDOI
TL;DR: In this paper, a total organic aqueous redox flow battery (OARFB) is reported, using low-cost and sustainable methyl viologen (MV, anolyte) and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (4-HO-TEMPO, catholyte), and benign NaCl supporting electrolyte.
Abstract: Increasing worldwide energy demands and rising CO2 emissions have motivated a search for new technologies to take advantage of renewables such as solar and wind energies. Redox flow batteries (RFBs) with their high power density, high energy efficiency, scalability (up to MW and MWh), and safety features are one suitable option for integrating such energy sources and overcoming their intermittency. However, resource limitation and high system costs of current RFB technologies impede wide implementation. Here, a total organic aqueous redox flow battery (OARFB) is reported, using low-cost and sustainable methyl viologen (MV, anolyte) and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (4-HO-TEMPO, catholyte), and benign NaCl supporting electrolyte. The electrochemical properties of the organic redox active materials are studied using cyclic voltammetry and rotating disk electrode voltammetry. The MV/4-HO-TEMPO ARFB has an exceptionally high cell voltage, 1.25 V. Prototypes of the organic ARFB can be operated at high current densities ranging from 20 to 100 mA cm2, and deliver stable capacity for 100 cycles with nearly 100% Coulombic efficiency. The MV/4-HO-TEMPO ARFB displays attractive technical merits and thus represents a major advance in ARFBs.

Journal ArticleDOI
TL;DR: This Review discusses how microorganisms can be explored for the production of next-generation biofuels, based on the ability of bacteria and fungi to use lignocellulose; through direct CO2 conversion by microalgae; using lithoautotrophs driven by solar electricity; or through the capacity of microorganisms to use methane generated from landfill.
Abstract: Global climate change linked to the accumulation of greenhouse gases has caused concerns regarding the use of fossil fuels as the major energy source. To mitigate climate change while keeping energy supply sustainable, one solution is to rely on the ability of microorganisms to use renewable resources for biofuel synthesis. In this Review, we discuss how microorganisms can be explored for the production of next-generation biofuels, based on the ability of bacteria and fungi to use lignocellulose; through direct CO2 conversion by microalgae; using lithoautotrophs driven by solar electricity; or through the capacity of microorganisms to use methane generated from landfill. Furthermore, we discuss how to direct these substrates to the biosynthetic pathways of various fuel compounds and how to optimize biofuel production by engineering fuel pathways and central metabolism.

Proceedings ArticleDOI
01 Oct 2016
TL;DR: This work uses different Deep Learning and Artificial Neural Network algorithms, such as Deep Belief Networks, AutoEncoder, and LSTM, to show their forecast strength compared to a standard MLP and a physical forecasting model in the forecasting the energy output of 21 solar power plants.
Abstract: Power forecasting of renewable energy power plants is a very active research field, as reliable information about the future power generation allow for a safe operation of the power grid and helps to minimize the operational costs of these energy sources. Deep Learning algorithms have shown to be very powerful in forecasting tasks, such as economic time series or speech recognition. Up to now, Deep Learning algorithms have only been applied sparsely for forecasting renewable energy power plants. By using different Deep Learning and Artificial Neural Network algorithms, such as Deep Belief Networks, AutoEncoder, and LSTM, we introduce these powerful algorithms in the field of renewable energy power forecasting. In our experiments, we used combinations of these algorithms to show their forecast strength compared to a standard MLP and a physical forecasting model in the forecasting the energy output of 21 solar power plants. Our results using Deep Learning algorithms show a superior forecasting performance compared to Artificial Neural Networks as well as other reference models such as physical models.

Journal ArticleDOI
TL;DR: It is predicted that this hydrogenase diversity supports H2-based respiration, fermentation and carbon fixation processes in both oxic and anoxic environments, in addition to various H1N1-sensing, electron-bifurcation and energy-conversion mechanisms.
Abstract: Recent physiological and ecological studies have challenged the long-held belief that microbial metabolism of molecular hydrogen (H2) is a niche process. To gain a broader insight into the importance of microbial H2 metabolism, we comprehensively surveyed the genomic and metagenomic distribution of hydrogenases, the reversible enzymes that catalyse the oxidation and evolution of H2. The protein sequences of 3286 non-redundant putative hydrogenases were curated from publicly available databases. These metalloenzymes were classified into multiple groups based on (1) amino acid sequence phylogeny, (2) metal-binding motifs, (3) predicted genetic organisation and (4) reported biochemical characteristics. Four groups (22 subgroups) of [NiFe]-hydrogenase, three groups (6 subtypes) of [FeFe]-hydrogenases and a small group of [Fe]-hydrogenases were identified. We predict that this hydrogenase diversity supports H2-based respiration, fermentation and carbon fixation processes in both oxic and anoxic environments, in addition to various H2-sensing, electron-bifurcation and energy-conversion mechanisms. Hydrogenase-encoding genes were identified in 51 bacterial and archaeal phyla, suggesting strong pressure for both vertical and lateral acquisition. Furthermore, hydrogenase genes could be recovered from diverse terrestrial, aquatic and host-associated metagenomes in varying proportions, indicating a broad ecological distribution and utilisation. Oxygen content (pO2) appears to be a central factor driving the phylum- and ecosystem-level distribution of these genes. In addition to compounding evidence that H2 was the first electron donor for life, our analysis suggests that the great diversification of hydrogenases has enabled H2 metabolism to sustain the growth or survival of microorganisms in a wide range of ecosystems to the present day. This work also provides a comprehensive expanded system for classifying hydrogenases and identifies new prospects for investigating H2 metabolism.

Journal ArticleDOI
TL;DR: In this paper, the authors reviewed the history of energy use and understood that new energy sources will usher in a new era following oil & gas, coal and wood one after another in the past time.

Journal ArticleDOI
TL;DR: It is posited that in carcinogenesis, aberrant cell signaling due to exaggerated and continually high lactate levels yields an inappropriate positive feedback loop that increases glucose uptake, glycolysis, lactate production and release, decreases mitochondrial function and clearance and upregulates glyCOlytic enzyme and monocarboxylate transporter expression thereby supporting angiogenesis, immune escape, cell migration, metastasis and self-sufficient metabolism.
Abstract: Herein, we use lessons learned in exercise physiology and metabolism to propose that augmented lactate production ('lactagenesis'), initiated by gene mutations, is the reason and purpose of the Warburg Effect and that dysregulated lactate metabolism and signaling are the key elements in carcinogenesis. Lactate-producing ('lactagenic') cancer cells are characterized by increased aerobic glycolysis and excessive lactate formation, a phenomenon described by Otto Warburg 93 years ago, which still remains unexplained. After a hiatus of several decades, interest in lactate as a player in cancer has been renewed. In normal physiology, lactate, the obligatory product of glycolysis, is an important metabolic fuel energy source, the most important gluconeogenic precursor, and a signaling molecule (i.e. a 'lactormone') with major regulatory properties. In lactagenic cancers, oncogenes and tumor suppressor mutations behave in a highly orchestrated manner, apparently with the purpose of increasing glucose utilization for lactagenesis purposes and lactate exchange between, within and among cells. Five main steps are identified (i) increased glucose uptake, (ii) increased glycolytic enzyme expression and activity, (iii) decreased mitochondrial function, (iv) increased lactate production, accumulation and release and (v) upregulation of monocarboxylate transporters MTC1 and MCT4 for lactate exchange. Lactate is probably the only metabolic compound involved and necessary in all main sequela for carcinogenesis, specifically: angiogenesis, immune escape, cell migration, metastasis and self-sufficient metabolism. We hypothesize that lactagenesis for carcinogenesis is the explanation and purpose of the Warburg Effect. Accordingly, therapies to limit lactate exchange and signaling within and among cancer cells should be priorities for discovery.

Journal ArticleDOI
TL;DR: In this article, a comprehensive review of thermoelectric (TE) technology encompassing the materials, applications, modelling techniques and performance improvement is carried out, including output power conditioning techniques.
Abstract: Thermoelectric (TE) technology is regarded as alternative and environmentally friendly technology for harvesting and recovering heat which is directly converted into electrical energy using thermoelectric generators (TEG). Conversely, Peltier coolers and heaters are utilized to convert electrical energy into heat energy for cooling and heating purposes The main challenge lying behind the TE technology is the low efficiency of these devices mainly due to low figure of merit (ZT) of the materials used in making them as well as improper setting of the TE systems. The objective of this work is to carry out a comprehensive review of TE technology encompassing the materials, applications, modelling techniques and performance improvement. The paper has covered a wide range of topics related to TE technology subject area including the output power conditioning techniques. The review reveals some important critical aspects regarding TE device application and performance improvement. It is observed that the intensified research into TE technology has led to an outstanding increase in ZT, rendering the use TE devices in diversified application a reality. Not only does the TE material research and TE device geometrical adjustment contributed to TE device performance improvement, but also the use of advanced TE mathematical models which have facilitated appropriate segmentation TE modules using different materials and design of integrated TE devices. TE devices are observed to have booming applications in cooling, heating, electric power generation as well as hybrid applications. With the generation of electric energy using TEG, not only does the waste heat provide heat source but also other energy sources like solar, geothermal, biomass, infra-red radiation have gained increased utilization in TE based systems. However, the main challenge remains in striking the balance between the conflicting parameters; ZT and power factor, when designing and optimizing advanced TE materials. Hence more research is necessary to overcome this and other challenge so that the performance TE device can be improved further.

Journal ArticleDOI
TL;DR: The current state of knowledge on the biochemistry and physiological functions of FAO is presented and the pathophysiological processes associated with FAO disorders are discussed.
Abstract: Mitochondrial fatty acid β-oxidation (FAO) is the major pathway for the degradation of fatty acids and is essential for maintaining energy homeostasis in the human body. Fatty acids are a crucial energy source in the postabsorptive and fasted states when glucose supply is limiting. But even when glucose is abundantly available, FAO is a main energy source for the heart, skeletal muscle, and kidney. A series of enzymes, transporters, and other facilitating proteins are involved in FAO. Recessively inherited defects are known for most of the genes encoding these proteins. The clinical presentation of these disorders may include hypoketotic hypoglycemia, (cardio)myopathy, arrhythmia, and rhabdomyolysis and illustrates the importance of FAO during fasting and in hepatic and (cardio)muscular function. In this review, we present the current state of knowledge on the biochemistry and physiological functions of FAO and discuss the pathophysiological processes associated with FAO disorders.

Journal ArticleDOI
TL;DR: In this paper, the authors provide a comprehensive summary of the current issues surrounding processing and containment of 129I, the isotope of greatest concern due to its long half-life of 1.6 × 107y and potential incorporation into the human body.

Journal ArticleDOI
TL;DR: In this paper, the characteristics and performances of different types of gasifiers under variable process parameters that will affect the yields of the end products as well as the composition of the gas.
Abstract: Currently, the use of biomass as an energy source has received a tremendous amount of interest from all over the world due to its advantage in providing a continuous feedstock supply. Moreover, when compared to fossil fuels, biomass fuels possess negligible sulfur concentrations, produce less ash, and generate far less emissions into the air. Biomass has a potential to be a very promising alternative source of raw material for syngas production due to its tremendous availability. Syngas can be produced from the gasification of a biomass. However, this process requires a significant amount of energy due to the endothermic behavior of the reaction. The energy consumption during the gasification process is a major constraint on the thermal efficiency and on the design of the gasifier. Therefore, a substantial improvement and the optimization of the available gasification process are very crucial in developing a sustainable utilization of these renewable natural resources. This review article focuses on highlighting the characteristics and performances of the different types of gasifiers under variable process parameters that will affect the yields of the end products as well as the composition of the gas. The various types of models used in the simulations, the optimization of the gasification conditions and the economic evaluation of the gasification process will also be discussed.

Journal ArticleDOI
TL;DR: In this paper, the authors provide an exposure to the necessity for deployment of renewable energy sources and the worldwide installed capacity of wind power as well as a review of various wind technologies in conjunction with their applications and devices of operation.
Abstract: Development of alternative energy sources has become a necessity as fossil energy resources are declining. At the same time, energy demand is rapidly increasing, putting the world on the verge of a global energy crisis. Moreover, the extensive use of conventional energy sources is polluting the environment and causing global warming. On the other hand, wind and other renewable energy sources are viable and clean alternatives to fossil fuels. Low operating cost and extensive availability make wind one of the most advantageous and effective renewable energy sources. This paper provides an exposure to the necessity for deployment of renewable energy sources and the worldwide installed capacity of wind power as well as a review of various wind technologies in conjunction with their applications and devices of operation. Furthermore, this paper discusses the cost of electric generation in wind power plants as well as the economic and environmental policies that advocate the installation of wind energy systems.

Journal ArticleDOI
TL;DR: From this review, the scientific community will obtain an understanding of the current state of ADS and ADN, their importance, and some encouragement and insight to take the research knowledge base to a higher level.

Journal ArticleDOI
TL;DR: This is a comprehensive review examining how organic waste and residues could be utilized in the future as reinforcements or additives for NFPCs from the perspective of the recently reported work in this field.

Journal ArticleDOI
TL;DR: In this paper, a swarm-based artificial bee colony (ABC) algorithm is applied for optimal sizing of components, and the results are compared with the results obtained from the standard software tool, hybrid optimization model for electric renewable (HOMER) and particle swarm optimization (PSO) algorithm.

Journal ArticleDOI
08 Nov 2016-ACS Nano
TL;DR: A green method for blood-brain barrier-penetrating albumin nanoparticle synthesis, with the capacity to coencapsulate different drugs and no need for cross-linkers, and a promising avenue for biomimetic delivery targeting the brain tumor based on combination therapy.
Abstract: Nutrient transporters have been explored for biomimetic delivery targeting the brain. The albumin-binding proteins (e.g., SPARC and gp60) are overexpressed in many tumors for transport of albumin as an amino acid and an energy source for fast-growing cancer cells. However, their application in brain delivery has rarely been investigated. In this work, SPARC and gp60 overexpression was found on glioma and tumor vessel endothelium; therefore, such pathways were explored for use in brain-targeting biomimetic delivery. We developed a green method for blood–brain barrier (BBB)-penetrating albumin nanoparticle synthesis, with the capacity to coencapsulate different drugs and no need for cross-linkers. The hydrophobic drugs (i.e., paclitaxel and fenretinide) yield synergistic effects to induce albumin self-assembly, forming dual drug-loaded nanoparticles. The albumin nanoparticles can penetrate the BBB and target glioma cells via the mechanisms of SPARC- and gp60-mediated biomimetic transport. Importantly, by mo...

Journal ArticleDOI
TL;DR: In this article, a state-of-the-art analysis of the available maximum power point tracking (MPPT) techniques and their comprehensive comparative analysis based on 110 standard research articles is presented.
Abstract: Unfilled gap of prolonged energy demand by conventional energy sources and consent of global warming as its vulnerable outcome provides a vent to search compatible option. Augmentation in use of solar energy reveled through last 3 decades portrays its heterogeneous rewards in the prevailing energy scenario. Nevertheless solar PV system arises as viable option in the critical power system era its low efficiency energy conversion attribute necessitates an efficient power conversion system. The nonlinearity of I–V (current–voltage) characteristic and its alteration for an assorted insolation and temperature values may enable the alteration in terminal voltage. This may deviates maximum power point due to which the available maximum power delivery to load can be differed. Literature of this field reiterated that the uniform insolation and partial shading condition demands undeniable need of maximum power point tracking. Nonetheless through investigation in this direction furnishes the availability of a bunch of such techniques; each of them posses its own pros and cones. This ubiquitous trait of available maximum power point tracking (MPPT) techniques unfolds the complexity in its precise selection. To diminish such complexity this paper offers a state of art of various MPPT technique and their comprehensive comparative analysis based on 110 standard research articles. The focus of this paper is to offer a better commencement and to furnish valued information for investigators of this field.

Journal ArticleDOI
TL;DR: A resilience-oriented service restoration method using microgrids to restore critical load after natural disasters is proposed in this paper, and the impacts of fault locations, available generation resources, and load priority on the restoration strategy are discussed.
Abstract: A resilience-oriented service restoration method using microgrids to restore critical load after natural disasters is proposed in this paper. Considering the scarcity of power generation resources, the concept of continuous operating time (COT) is introduced to determine the availability of microgrids for critical load restoration and to assess the service time. Uncertainties induced by intermittent energy sources and load are also taken into account. The critical load restoration problem is modeled as a chance-constrained stochastic program. A Markov chain-based operation model is designed to describe the stochastic energy variations within microgrids, based on which the COT is assessed. A two-stage heuristic is developed for the critical load restoration problem. First, a strategy table containing the information of all feasible restoration paths is established. Then the critical load restoration strategy is obtained by solving a linear integer program. Numerical simulations are performed on the IEEE 123-node feeder system under several scenarios to demonstrate the effectiveness of the proposed method. The impacts of fault locations, available generation resources, and load priority on the restoration strategy are discussed.