Epworth Sleepiness Scale

About: Epworth Sleepiness Scale is a research topic. Over the lifetime, 4742 publications have been published within this topic receiving 155088 citations.

Sleep Disorders in Machado–Joseph Disease: Frequency, Discriminative Thresholds, Predictive Values, and Correlation with Ataxia-Related Motor and Non-Motor Features

Abstract: Sleep disorders are common complaints in patients with neurodegenerative diseases such as spinocerebellar ataxia type 3 (SCA3) or Machado–Joseph disease (MJD)—SCA3/MJD. We evaluated the frequency of sleep disorders in SCA3/MJD patients against controls matched by age and gender, and correlated data with demographic and clinical variables. The main sleep disorders evaluated were rapid eye movement (REM) sleep behavior disorder (RBD), restless leg syndrome (RLS), and excessive daytime sleepiness (EDS). We recruited 40 patients with clinical and molecular-proven SCA3/MJD and 38 controls. We used the following clinical scales to evaluate our primary outcome measures: RBD Screening Questionnaire, International RLS Rating Scale, and Epworth Sleepiness Scale. To evaluate ataxia-related motor and non-motor features, we applied the International Cooperative Ataxia Rating Scale, the Scale for the Assessment and Rating of Ataxia, and the Unified Parkinson’s Disease Rating Scale part III. Psychiatric manifestations were tested with the Hamilton Anxiety Scale, and Beck Depression Inventory. The frequency of RBD and RLS were significantly higher in the SCA3/MJD group than in the control group (p < 0.001). There was no difference between both groups with regard to EDS. The accuracy of RDBSQ to discriminate between cases and controls was considered the best area under the ROC curve (0.86). Within-SCA3/MJD group analysis showed that anxiety and depression were significantly correlated with RDB, but not with RLS. Additionally, depression was considered the best predictive clinical feature for RDB and EDS.

The relationship between excessive daytime sleepiness and depressive and anxiety disorders in women.

Abstract: Objective:Excessive daytime sleepiness (EDS) is a common clinical symptom that affects women more than men. However, the association of excessive sleepiness with depressive and anxiety disorders in the broader population is unclear. The aim of this study was, therefore, to examine the association between excessive daytime sleepiness as measured by the Epworth Sleepiness Scale, and depressive and anxiety disorders in a population-based sample of women.Methods:Using the Structured Clinical Interview for DSM-IV Disorders (Non-Patient) (SCID-I/NP), 944 women aged 20–97 years (median 49 years, IQR 33–65 years) were assessed for depressive and anxiety disorders as part of the Geelong Osteoporosis Study. EDS was assessed using the Epworth Sleepiness Scale (ESS, cut-off > 10). Lifestyle factors were documented by self-report, height and weight were measured, and socioeconomic status categorised according to the Index of Relative Socio-Economic Advantage and Disadvantage.Results:Overall, 125 (13.2%) of the women w...

Oral lichen planus: salival biomarkers cortisol, immunoglobulin A, adiponectin.

Abstract: Background Oral lichen planus (OLP) is a chronic mucocutaneous disease, inflammatory and autoimmune in character, in which the pathogenesis is not fully understood Psychological stress has also been implicated in triggering or exacerbating the disease Objective The aim of this study was to evaluate the psychological profile, sleep, and salivary biological markers—cortisol, immunoglobin A (IgA), and adiponectin – in patients with oral lichen planus (OLP) Methods The sample consisted of 65 patients (33 with OLP and 32 control patients) Patients completed hospital anxiety and depression scales (HADD, HADA) Questionnaires were used to assess sleepiness: the Pittsburgh sleep quality index (PSQI) and the Epworth sleepiness scale (ESS) A visual analog scale (VAS) was used for rating pain Unstimulated whole saliva was evaluated, together with total proteins: cortisol, IgA, and adiponectin Results Patients with OLP obtained significantly higher HADA and PSQI scores than control subjects (P = 0001, P = 0012, respectively) Total salivary protein (flow at rest) analysis found that total proteins were higher in the OLP group (P = 0001) In the OLP group, IgA was 803 ± 513 vs the control group 489 ± 328 (P = 0005) Mean cortisol was 05 ± 03 μg/dl in the OLP group vs 04 ± 02 μg/dl in the control group (P = 0010) The OLP group showed a correlation between the HADA variable and pain (r = 0358; P = 0041), HADD (r = 0568; P = 0001), and PSQI (r = 0537; P = 0001) Conclusions OLP patients presented worse psychological profiles and sleep disturbances, as well as higher values for IgA, cortisol, and total proteins than control subjects

Excessive daytime sleepiness and its risk factors in incident Parkinson's disease

Abstract: Excessive daytime sleepiness (EDS) can be a feature of various neurodegenerative diseases including Parkinson's disease (PD) EDS puts patients at increased risk of accidents while driving and it is important to identify such patients in order to advise them and others about their individual level of risk and the potential therapeutic options available to them The most commonly used method for assessing EDS in the clinic is the Epworth Sleepiness Scale (ESS)—a self-completed questionnaire which scores the tendency to fall asleep during eight everyday situations The final score ranges from 0–24, with scores greater than 10 generally considered pathological This questionnaire has been widely used in unselected PD cohorts, with the prevalence of EDS ranging from 3–50%1 Although there is a general consensus that dopaminergic medications contribute to EDS in PD,2 there is less agreement about other risk factors One possible explanation for these disparities is that heterogeneous PD cohorts were studied at different points in their disease course Some studies have also suggested that the Catechol O-methyltransferase ( COMT ) val158met polymorphism (which is known to significantly alter enzyme activity) may be associated with EDS In this study, we report on the prevalence of EDS and its risk factors in a population-representative incident PD cohort This cohort was recruited between December 2000 and December 2002, when we attempted to collect all newly diagnosed cases of parkinsonism in the country …