Topic
Esterase
About: Esterase is a research topic. Over the lifetime, 7622 publications have been published within this topic receiving 168270 citations.
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TL;DR: Results suggest that tannases may contribute to plant cell wall degradation by cleaving some of the cross-links existing between cell wall polymers.
75 citations
TL;DR: Results showed that the cholesterol esterases in the liver and the pancreas are very similar and possibly identical proteins.
74 citations
TL;DR: In this paper, Steinmetz et al. report the mutational analysis of other conserved residues possessing reactive side chains Arg84, Lys192, Lys 192, Thr384, Glu399, and Ser471, along with partially conserved Glu398 and Lys489.
74 citations
TL;DR: Analysis of albumin which has reacted with p-nitrophenyl acetate indicate that two tyrosyl hydroxyl groups on the protein are rapidly acetylated by the ester.
74 citations
TL;DR: The apparently normal response to intradermal C'1 esterase developed by individuals with an acquired specific deficiency of C'3 suggests that the vasoactive substance may be derived from one of the early reacting complement components.
Abstract: When purified human C′1 esterase is injected intradermally in man, increased vascular permeability results. This effect is not blocked by soybean trypsin inhibitor and is not abolished by pretreatment with the antihistamine, pyribenzamine, or by compound 48/80. Thus, the effect is not due to the release of endogenous histamine. The decreased permeability response of individuals with a specific hereditary deficiency of C′2 is evidence for the complement-dependent nature of this reaction. The apparently normal response to intradermal C′1 esterase developed by individuals with an acquired specific deficiency of C′3 suggests that the vasoactive substance may be derived from one of the early reacting complement components. Characteristic attacks of angioedema have been provoked by the intradermal injection of human C′1 esterase in two individuals with hereditary angioneurotic edema. Patients with hereditary angioneurotic edema are unresponsive to intradermal injections of C′1 esterase immediately after attacks.
74 citations