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Showing papers on "Fagonia cretica published in 2019"


Journal ArticleDOI
15 May 2019
TL;DR: In this article, an efficient bioreducing agent from Fagonia cretica extract was used to synthesize silver nanoparticles (NPs) with the advantage of eco-friendliness over chemical and physical methods.
Abstract: Silver nanoparticles (NPs) were synthesized using an efficient bioreducing agent from Fagonia cretica extract having the advantage of eco-friendliness over chemical and physical methods. The sharp color change and appearance of representative absorption peaks in the UV-visible spectra confirm the quick reduction of the Ag salt and evolution of Ag NPs. Morphological and structural aspects showed that the resulting Ag NPs are highly crystalline with an average size of 16 nm. Furthermore, compositional analysis of the extract confirmed the existence of active bioreducing and stabilizing agents in the Fagonia cretica extract. Furthermore, various concentrations of AgNO3 and the Fagonia cretica extract were employed to obtain a higher yield with better stability of Ag NPs. The resulting Ag NPs showed effective antibacterial activity against Proteus vulgaris, Escherichia coli, and Klebsiella pneumoniae. It is found that the Ag NPs induce maximum production of reactive oxygen species (ROS) in Proteus vulgaris as compared to Escherichia coli and Klebsiella pneumoniae which induce cell toxicity, while ROS production in the presence of Ag NPs is 30% higher than that in the presence of only the plant extract and control in all three bacterial strains. Thus, present findings show that plant extracts can be a useful natural resource to prepare functional nanomaterials for targeted applications especially in the field of biotechnology.

58 citations


Journal ArticleDOI
TL;DR: In this article, the authors evaluated the bio-reducing activity and various biochemical potential of Fagonia cretica NPs with different ethanol-water fraction mixture and found that 50% ethanol water fraction has potentially harmful molecules (among all fractions) primarily involved in bio reducing.
Abstract: Objective: Evaluating the bio-reducing activity and various potential, annotates the biological entitties of Fagonia cretica. Method: By fractionating the crude extract with different ethanol-water fraction mixture. This substantiates the reduction potential for the biological synthesis of AgNPs, its antioxidant, anti-urease and anti-Tyrosinase activity. Results: UV-visible spectra confirm the bio-reducing potential for Ag NPs with the optimized 50% ethanol-water fraction mixture. Transmission electron microscopy (TEM) confirmed the round shaped AgNPs with an average size of 16 nm in optimized 50% fraction mixture. Further evaluating Ethanol-water fraction with 90% and 70% of plant extract showed more potentials for Anti-Tyrosinase and Anti-urease activity. Moreover, diluted 30% fraction exhibits two folds higher Anti-oxidant and Anti urease activity. Conclusion: Overall, this work showed that 50% Ethanol-water fraction has potentially active molecules (among all fractions) primarily involved in bio-reducing potential of Ag NPs and enzymatic assay while 90% mixture proved to be least active. This study suggested electing the optimum mixture fraction of 50% ethanol-water in order to screen the bioactive compounds and to inculcate their activity status for clinical trials.

13 citations


Journal ArticleDOI
TL;DR: It was concluded that the AgNP prepared from F. cretica extract were spherical and aggregated and were found effective against different clinical isolates of bacteria.
Abstract: Fagonia cretica L. is a known medicinal plant containing important biomolecules. The present study was designed to prepare the silver nanoparticles (AgNP) from F. cretica L. that has never ...

5 citations


Journal ArticleDOI
TL;DR: Potential activity as antimicrobials against bacteria and fungi Bacillus subtilis is maximum in methanol extract and minimum against Staphylococcus aureus in chloroform extract.
Abstract: The aim of the present study is to determine antimicrobial potential activity of Fagonia cretica and Desmostachya bipinnata plant parts to look into possible natural therapy agents. Fagonia cretica (Linn.) is most valuable therapeutic medicinal plant, commonly known as Dhamasa and belong to Zygophyllaceae family and Desmostachya bipinnata is also valuable medicinal plant, commonly known as Kusha or Dabh and belong to Poaceae family‎. Fagonia cretica and Desmostachya bipinnata have a good medicinal property and used as: urinary disorder, abdominal pain, chronic fever, cancer, dysentery and menorrhagia, and as a diuretic and a blood purifier. Selective plant parts were also used as medicine contents in pharmaceuticals. Antibacterial and antifungal activity has to be done from various selective medicinal plant parts. Potential activity as antimicrobials against bacteria and fungi Bacillus subtilis is maximum in methanol extract and minimum against Staphylococcus aureus in chloroform extract. Fagonia cretica most valuable medicinal plant, used as anti breast cancer drug. Keywords: Fagonia cretica; Desmostachya bipinnata; Antimicrobials Activity; Methanol extract; Chloroform extract; Fungi strains; Bacterial strains.

3 citations