Topic
Fertility
About: Fertility is a research topic. Over the lifetime, 29988 publications have been published within this topic receiving 681106 citations.
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TL;DR: To the authors' knowledge little is known regarding psychological outcomes in female cancer patients who undergo fertility preservation counseling/consultation (FPC), with or without fertility preservation (FP).
Abstract: BACKGROUND
For many female cancer survivors, the preservation of reproductive potential is central to quality of life (QOL), and concerns regarding infertility may affect treatment decisions. Despite the existence of several consensus guidelines supporting routine fertility preservation consultation, to the authors' knowledge little is known regarding psychological outcomes in female cancer patients who undergo fertility preservation counseling/consultation (FPC), with or without fertility preservation (FP).
METHODS
This literature review examined the effect of FPC alone, or with FP, on psychological outcomes including satisfaction, decisional regret, and QOL. PubMed and PsychINFO were systematically searched for English-language publications from the earliest available publication date of each database through March 2015. Among 111 unique articles concerning oncofertility, 13 met inclusion criteria: peer-reviewed articles reporting primary data regarding satisfaction and psychological outcomes among women who underwent FPC alone or with FP.
RESULTS
A majority of women receiving FPC reported that the possibility of FP was instrumental to improved coping. Receiving FPC reduced long-term regret and dissatisfaction concerning fertility, and was associated with improved physical QOL and trends toward improved psychological QOL. Women also desired prompt, standardized, and written information addressing perceived unmet needs specific to oncofertility. Offering FPC was perceived as critical regardless of age or parity.
CONCLUSIONS
To the best of the authors' knowledge, little research to date has addressed the impact of FPC alone, or with FP, on QOL in women with cancer. Clinicians should recognize the existing evidence base supporting the psychological benefit of prompt FPC. Future research must be conducted to elucidate the long-term psychosocial effects of FP. Cancer 2015;121:3938–3947. © 2015 American Cancer Society.
162 citations
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TL;DR: This review summarizes the current task force recommendations for the assessment and management of female reproductive complications after treatment for childhood, adolescent, and young adult cancers and discusses experimental pretreatment as well as post-treatment fertility preservation strategies.
Abstract: Purpose As more young female patients with cancer survive their primary disease, concerns about reproductive health related to primary therapy gain relevance. Cancer therapy can often affect reproductive organs, leading to impaired pubertal development, hormonal regulation, fertility, and sexual function, affecting quality of life. Methods The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancer (COG-LTFU Guidelines) are evidence-based recommendations for screening and management of late effects of therapeutic exposures. The guidelines are updated every 2 years by a multidisciplinary panel based on current literature review and expert consensus. Results This review summarizes the current task force recommendations for the assessment and management of female reproductive complications after treatment for childhood, adolescent, and young adult cancers. Experimental pretreatment as well as post-treatment fertility preservation strategies, inc...
162 citations
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TL;DR: The relatively low fertility expectations among those prevented from working by the unavailability of child care suggests that not just current employment, but also the intention of desire to work, is related to fertility behavior.
Abstract: This study examines the extent to which the unavailability of satisfactory child care is a constrait on employment for mothers with children under five years of age. It also explores some of the social and demographic correlates of constrait and the role child care plays in the relationship between labor-force participation and fertility. The analysis is based on data from the June 1977 Current Population Survey for the United States. A substantial minority of mothers with young children, both nonemployed and employed, feel that if child care were available at reasonable cost, they would seek employment or work more hours. Child-care constrait seems to be most prevalent among mothers who are young, black, single, with low education and with little income. The relatively low fertility expectations among those prevented from working by the unavailability of child care suggests that not just current employment, but also the intention of desire to work, is related to fertility behavior. The differential in bi...
162 citations
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TL;DR: Paternal age is rising within the USA among all regions, races and education levels, although it varies by race, geographic region and paternal education level, and racial/ethnic differences were identified.
Abstract: Study question How has the mean paternal age in the USA changed over the past 4 decades? Summary answer The age at which men are fathering children in the USA has been increasing over time, although it varies by race, geographic region and paternal education level. What is known already While the rise in mean maternal age and its implications for fertility, birth outcomes and public health have been well documented, little is known about paternal characteristics of births within the USA. Study design, size, duration A retrospective data analysis of paternal age and reporting patterns for 168 867 480 live births within the USA since 1972 was conducted. Participants/materials, setting, methods All live births within the USA collected through the National Vital Statistics System (NVSS) of the Centers for Disease Control and Prevention (CDC) were evaluated. Inverse probability weighting (IPW) was used to reduce bias due to missing paternal records. Main results and the role of chance Mean paternal age has increased over the past 44 years from 27.4 to 30.9 years. College education and Northeastern birth states were associated with higher paternal age. Racial/ethnic differences were also identified, whereby Asian fathers were the oldest and Black fathers were the youngest. The parental age difference (paternal age minus maternal age) has decreased over the past 44 years. Births to Black and Native American mothers were most often lacking paternal data, implying low paternal reporting. Paternal reporting was higher for older and more educated women. Limitations, reasons for caution Although we utilized IPW to reduce the impact of paternal reporting bias, our estimates may still be influenced by the missing data in the NVSS. Wider implications of the findings Paternal age is rising within the USA among all regions, races and education levels. Given the implications for offspring health and demographic patterns, further research on this trend is warranted. Study funding/competing interest(s) No funding was received for this study and there are no competing interests. Trial registration number N/A.
162 citations
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TL;DR: The recent report of a live birth after transplantation of human ovarian tissue has reinforced the clinical potential of ovarian tissue banking for fertility preservation and reviewed the current advances in fertility preservation strategies and discussed future directions with an emphasis on ovarian tissue cryobanking.
162 citations