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Fertility

About: Fertility is a research topic. Over the lifetime, 29988 publications have been published within this topic receiving 681106 citations.


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Journal ArticleDOI
TL;DR: Proper information given early in the course of trying to achieve pregnancy is likely to reduce time to conception for many couples, and also to reduce unnecessary intervention and cost.

143 citations

Journal ArticleDOI
TL;DR: The most efficient way to breed for improved fertility is to construct a selection index using the genetic and phenotypic parameter estimates of all traits of interest in addition to their respective economic values.
Abstract: In recent years there has been considerable genetic progress in milk production. Yet, increases in yield have been accompanied by an apparent lengthening of calving intervals, days open, days to first heat and a decline in conception rates, which appears to be both at the genetic and phenotypic level. Fertility has a high relative economic value compared to production traits such as protein, making it attractive to include in a breeding programme. To do this there needs to be genetic variance in fertility. Measures of fertility calculated from service dates have a small genetic compared to phenotypic variance, hence heritability estimates are small, typically less than 5%, although coefficients of genetic variance are comparable to those of production traits. Heritabilities of commencement of luteal activity determined using progesterone profiles are generally higher, and have been reported as being from 0.16 to 0.28, which could be because of a more precise quantification of genetic variance, as management influences such as delaying insemination and heat detection rates are excluded. However, it might not be the use of progesterone profiles alone, as days to first heat observed by farm staff has a heritability of 0.15. The most efficient way to breed for improved fertility is to construct a selection index using the genetic and phenotypic parameter estimates of all traits of interest in addition to their respective economic values. Index traits for fertility could include measures such as calving interval, days open, days to first service, or days to first heat but there may also be alternative measures. Examples include traits related to energy balance, such as live weight and condition score (change), both of which have higher heritabilities than fertility measures and have genetic correlations of sufficient magnitude to make genetic progress by using them feasible. To redress the balance between fertility and production, some countries already publish genetic evaluations of fertility including: Denmark, Finland, France, Germany, Israel, The Netherlands, Norway and Sweden.

143 citations

Journal ArticleDOI
TL;DR: Healthcare providers need training on how and when to broach fertility issues with patients, emphasizing open communication and early disclosure.

143 citations

Journal ArticleDOI
TL;DR: A review of recent literature on the prevalence and effects of illicit drug use on male fertility and to aid health professionals when counseling infertile men whose social history suggests drug use can be an important cause of male factor infertility and includes use of anabolic androgenic steroids, marijuana, cocaine, methamphetamines, and opioid narcotics as mentioned in this paper.
Abstract: One-third of infertile couples may have a male factor present. Illicit drug use can be an important cause of male factor infertility and includes use of anabolic-androgenic steroids, marijuana, opioid narcotics, cocaine, and methamphetamines. The use of these illicit drugs is common in the United States, with a yearly prevalence rate for any drug consistently higher in males compared with females. We aim to provide a review of recent literature on the prevalence and effects of illicit drug use on male fertility and to aid health professionals when counseling infertile men whose social history suggests illicit drug use. Anabolic-androgenic steroids, marijuana, cocaine, methamphetamines, and opioid narcotics all negatively impact male fertility, and adverse effects have been reported on the hypothalamic-pituitary-testicular axis, sperm function, and testicular structure. The use of illicit drugs is prevalent in our society and likely adversely impacting the fertility of men who abuse drugs.

143 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20241
20232,042
20223,958
20211,098
20201,105
20191,047