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Fertility

About: Fertility is a research topic. Over the lifetime, 29988 publications have been published within this topic receiving 681106 citations.


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Journal ArticleDOI
TL;DR: This article used age-at-school-entry policies to identify the effect of female education on fertility and infant health and found that school entry policies manipulate primarily the education of young women at risk of dropping out of school.
Abstract: This paper uses age-at-school-entry policies to identify the effect of female education on fertility and infant health. We focus on sharp contrasts in schooling, fertility, and infant health between women born just before and after the school entry date. School entry policies affect female education and the quality of a woman's mate and have generally small, but possibly heterogeneous, effects on fertility and infant health. We argue that school entry policies manipulate primarily the education of young women at risk of dropping out of school.

340 citations

Journal ArticleDOI
TL;DR: In this paper, the authors summarized major factors affecting fertility in obesity and found that early onset of obesity favours the development of menses irregularities, chronic oligo-anovulation and infertility in the adult age.
Abstract: Purpose of reviewTo summarize major factors affecting fertility in obesity.Recent findingsFertility can be negatively affected by obesity. In women, early onset of obesity favours the development of menses irregularities, chronic oligo-anovulation and infertility in the adult age. Obesity in women c

338 citations

Journal ArticleDOI
23 Apr 1998-Nature
TL;DR: A systematic test of two alternatives of the human menopause using field data from two species in which grandmothers frequently engage in kin-directed behaviour finds that elderly females do not suffer increased mortality costs of reproduction, nor do post-reproductive females enhance the fitness of grandchildren or older children.
Abstract: In female mammals, fertility declines abruptly at an advanced age. The human menopause is one example, but reproductive cessation has also been documented in non-human primates, rodents, whales, dogs, rabbits, elephants and domestic livestock. The human menopause has been considered an evolutionary adaptation, assuming that elderly women avoid the increasing complications of continued childbirth to better nurture their current children and grandchildren. But an abrupt reproductive decline might be only a non-adaptive by-product of life-history patterns. Because so many individuals die from starvation, disease and predation, detrimental genetic traits can persist (or even be favoured) as long as their deleterious effects are delayed until an advanced age is reached, and, for a given pattern of mortality, there should be an age by which selection would be too weak to prevent the onset of reproductive senescence. We provide a systematic test of these alternatives using field data from two species in which grandmothers frequently engage in kin-directed behaviour. Both species show abrupt age-specific changes in reproductive performance that are characteristic of menopause. But elderly females do not suffer increased mortality costs of reproduction, nor do post-reproductive females enhance the fitness of grandchildren or older children. Instead, reproductive cessation appears to result from senescence.

335 citations

Journal ArticleDOI
TL;DR: Although the total number of cases involved is small, a number of general principles emerge and individuals of either sex show a degree of variation in their response to irradiation.
Abstract: Increasing numbers of young people are now being cured of certain neoplasms by radiotherapy and chemotherapy. Such people will naturally wish to lead a normal life and possibly to have children. Therefore the question of the effect of radiation and cytotoxic drugs on the reproductive capacity of these patients has become important. The purpose of this report is to review the information available on the effect of radiation on fertility in man. Direct information on radiation effects on human fertility is available from reports on therapeutic exposure and deliberate experimental exposure. Although the total number of cases involved is small, a number of general principles emerge. In males, fractionated irradiation of the testes may be more harmful than acute, at least up to total doses of about 600 cGy (rad). Fractionated doses greater than 35 cGy cause aspermia, the time taken for recovery increasing with dose, and after more than 200 cGy aspermia may be permanent. In females, response varies with age as well as dose. For example, 400 cGy may cause a 30% incidence of sterility in young women, but in women aged above 40 years it results in 100% sterility. However, individuals of either sex show a degree of variation in their response to irradiation.

333 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20241
20232,042
20223,958
20211,098
20201,105
20191,047