Topic
Fetus
About: Fetus is a research topic. Over the lifetime, 21567 publications have been published within this topic receiving 646380 citations. The topic is also known as: foetus & fœtus.
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TL;DR: Prenatal alcohol exposure, blood alcohol concentrations and alcohol elimination rates for the mother, fetus and newborn were analyzed in this article, showing that pregnant women are at risk of exposure to alcohol during pregnancy.
Abstract: Prenatal alcohol exposure, blood alcohol concentrations and alcohol elimination rates for the mother, fetus and newborn
128 citations
TL;DR: The results indicate that corticosteroids do not induce premature labor in primates and, on the contrary, long-term dexamethasone administration is associated with prolonged pregnancy and suppression of estrogen biosynthesis.
128 citations
TL;DR: Growth of the human fetal adrenal cortex involves cellular hyperplasia, mainly in the DZ and to a lesser extent in the FZ, which is probably dependent on ACTH; and apoptosis occurs predominantly in the inner cortical compartment and may be responsible for the rapid regression of theFZ after birth, a process that may be regulated by activin A and/or TGFbeta.
Abstract: After 10–15 weeks of gestation, the human fetal adrenal cortex undergoes rapid growth due to enlargement of a specialized cortical compartment known as the fetal zone (FZ). Soon after birth, the FZ regresses and the adult zonation pattern develops at least in part from cells derived from the persistent definitive zone (DZ), a thin layer of tightly packed cells surrounding the FZ. We postulated that growth of the fetal adrenal cortex involves zone-specific cellular hyperplasia, whereas the postnatal involution of the FZ is due to apoptosis. Therefore, we investigated the pattern of cellular proliferation and death in the FZ and DZ of the human fetal and postnatal adrenal cortex using immunohistochemical staining for proliferating cell nuclear antigen as a marker of mitosis and in situ detection of DNA fragmentation as a marker of apoptosis. Between 10–14 weeks’ gestation, the mitotic indexes (percentage of proliferating cell nuclear antigen-positive cells) in the DZ (26.46 ± 2.95%) and in the FZ (21.26 ± 2...
128 citations
TL;DR: The present investigation appears to indicate that the adverse effects of nicotine to the fetus are due to the combined effects of the reduced uterine blood flow and the transmitted nicotine toThe fetus.
128 citations
TL;DR: Results of measuring radioactivity in lipids of fetal tissues suggest that the metabolic pathways followed by palmitic acid-1-C 14 in the fetus are similar to those in the adult rabbit.
128 citations