Topic
Flavanone
About: Flavanone is a research topic. Over the lifetime, 1965 publications have been published within this topic receiving 54729 citations. The topic is also known as: flavanones.
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TL;DR: The analysis of the flavonoids present in orange nectar revealed that the flavanone hesperidin (hesperetin-7-rutinoside) was the major flavonoid detected and, therefore, this should be the main source of the hesperetin found in citrus honey.
Abstract: Seventeen flavonoid aglycones were identified in various experimental and commercial citrus honey samples by HPLC analysis The flavanone hesperetin was detected in all samples This flavanone was not detected in any of the honey samples, from diverse floral origin (including rosemary, lavender, sunflower, almond, sweet chestnut, white clover, Erisarum, Robinia, Rhododendron, Tilia, Prosopis, Eucalyptus and Calluna honeys) previously investigated The analysis of the flavonoids present in orange nectar revealed that the flavanone hesperidin (hesperetin-7-rutinoside) was the major flavonoid detected and, therefore, this should be the main source of the hesperetin found in citrus honey Hesperetin should be produced by hydrolysis of hesperidin by the bee enzymes present in honey These results suggest that hesperetin could be used as a marker for the botanical origin of citrus honey
161 citations
TL;DR: Analysis of data revealed that shade had notable effects on both flavonoid (including catechins, O -glycosylated flavonols and proanthocyanins (PAs) and lignin biosynthesis, but had no significant effect on anthocyanin accumulation, and it was suggested that polymerization of catech ins and glycosylation of flavonol might be key pathways of Flavonoid metabolism in tea leaves affected by shade treatment.
160 citations
TL;DR: In studies on unsaturated ketones, it is found that chalkone, flavanones, flavone and some of their derivatives, for example, buteine (2,4,3′,4′-tetrahydroxychalkone) showed a marked inhibition of the growth of Staph.
Abstract: INVESTIGATIONS by A. R. Todd1, H. Rinderknecht2, W. B. Geiger3 and others have shown that many unsaturated ketones with the grouping —C = C—CO—, also present in a number of naturally occurring antibiotics, possess antibacterial action. In our studies on unsaturated ketones, we found that chalkone, flavanone, flavone and some of their derivatives, for example, buteine (2,4,3',4'-tetrahydroxychalkone). a substance of vegetable origin, showed a marked inhibition of the growth of Staph. aureus. Also extracts of plants containing flavanones, flavones or flavonoles were found to be bacteriostatic4. Furthermore, we have prepared a number of synthetic chalkones of which some compounds suppressed the growth at high dilutions.
158 citations
TL;DR: All flavanones investigated here showed higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF) and the cytot toxicity of compound 2 and the Diels-Alder type flavanone sanggenon C isolated from Morus cathayana were the most potent.
Abstract: A new pyranoflavanone, sanggenol L (1), a Diels-Alder type adduct regarded as a cycloaddition product of a dehydrogeranylflavanone and a prenylchalcone, sanggenol M (2), along with four new 2-arylbenzofurans with isoprenoid units, mulberrofurans W-Z (3-6), were isolated together with 10 known flavonoids from Chinese Morus mongolica. The structures of these novel compounds were elucidated by spectroscopic methods. All flavanones investigated here showed higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF). Among them, the cytotoxicity of compound 2 and the Diels-Alder type flavanone sanggenon C (7) isolated from Morus cathayana were the most potent. On the other hand, seven 2-arylbenzofurans exhibited lower cytotoxicity and tumor specificity as compared with flavanones.
158 citations
TL;DR: Findings show that 4'-hydroxylation results in either no change or very little change in IC50 for flavanone, isoflavone and isoflavanone as well as other ring A hydroxylated flavones.
153 citations