Flavanone

TL;DR: Aiming at expanding the pool of analogues of the flavanone core towards better multidrug resistance (MDR) reversal agents, alkylation reactions and chemical modification of the carbonyl moiety was performed and showed that dimethylation promotes binding to a modulator-binding site.

TL;DR: In this article, it was shown that dihydroflavonols containing orthodihydroxyl groups in the A-ring and 5-deoxy dihydronols (through the 3-hydroxy-4-oxo-system) can form acid-labile complexes with AlCl3 in MeOH.

TL;DR: The P. vulgaris enzyme showed similarities to the enzyme recently purified from cell cultures of Petroselinum hortense with respect to molecular weight, pH optimum, ability to catalyse 14 CO 2 exchange between NaH 14 CO 3 and malonyl-CoA, and overall response of naringenin formation to varying thiol concentration, but appeared much less stable.