Flavanone

About: Flavanone is a research topic. Over the lifetime, 1965 publications have been published within this topic receiving 54729 citations. The topic is also known as: flavanones.

Hydroxylation decoration patterns of flavonoids in horticultural crops: chemistry, bioactivity, and biosynthesis

Abstract: Abstract Flavonoids are the most widespread polyphenolic compounds and are important dietary constituents present in horticultural crops such as fruits, vegetables, and tea. Natural flavonoids are responsible for important quality traits, such as food colors and beneficial dietary antioxidants, and numerous investigations have shown that intake of flavonoids can reduce the incidence of various non-communicable diseases. Analysis of the thousands of flavonoids reported so far has shown that different hydroxylation modifications affect their chemical properties and nutritional values. These diverse flavonoids can be classified based on different hydroxylation patterns in the B, C, and A rings and multiple structure–activity analyses have shown that hydroxylation decoration at specific positions markedly enhances their bioactivities. This review focuses on current knowledge concerning hydroxylation of flavonoids catalyzed by several different types of hydroxylase enzymes. Flavonoid 3′-hydroxylase (F3′H) and flavonoid 3′5′-hydroxylase (F3′5′H) are important enzymes for the hydroxylation of the B ring of flavonoids. Flavanone 3-hydroxylase (F3H) is key for the hydroxylation of the C ring, while flavone 6-hydroxylase (F6H) and flavone 8-hydroxylase (F8H) are key enzymes for hydroxylation of the A ring. These key hydroxylases in the flavonoid biosynthesis pathway are promising targets for the future bioengineering of plants and mass production of flavonoids with designated hydroxylation patterns of high nutritional importance. In addition, hydroxylation in key places on the ring may help render flavonoids ready for degradation, and the catabolic turnover of flavonoids may open the door for new lines of inquiry.

Antioxidant and pro-oxidant evaluation of a Potentilla alba L. rhizome extract

Abstract: Using spectrophotometric methods, a H(2) O-soluble Potentilla alba L rhizome extract was evaluated phytochemically, ie, the total phenol, flavonoid, flavonol, flavanone, and proanthocyanidin contents were determined, and its antioxidant and pro-oxidant properties, ie, the Fe(III) reductive and the Fe(II) chelating properties, the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH(*)), N,N-dimethyl-p-phenylenediamine (DMPD(*+)), and superoxide anion radical (O2*-)-scavenging activities, the capacity to inhibit hydroxyl radical (HO(*))-mediated deoxy-D-ribose and phospholipid degradation, and the interaction with the Cu-catalyzed HO(*) -mediated DNA degradation, were determined The extract was found to contain a range of phenolic compounds recognized to possess strong antioxidant-like properties Moreover, the extract demonstrated dose-dependent activities in all the antioxidant assays with the exception of the DNA-degradation assay, where the components within the extract interfered with the assay components at concentrations ≥100 mg/ml Potentilla species are known for their curative properties, with aerial/subterranean parts being prescribed for numerous indications The data presented here suggests, though does not conclude, that the rhizomes contain compounds possessing a range of antioxidant-related properties, which may underpin the therapeutic, viz, anti-inflammatory and adaptogenic effects, ascribed to species of this genus