Topic
Flavanone
About: Flavanone is a research topic. Over the lifetime, 1965 publications have been published within this topic receiving 54729 citations. The topic is also known as: flavanones.
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TL;DR: A new isoprenylated sanggenon-type flavanone, nigrasin K, together with three known analogs and five known Diels–Alder adducts were isolated from the twigs of Morus nigra and showed significant inhibitory effects on mushroom tyrosinase.
14 citations
TL;DR: Four new chalcones, a new flavanone, (9), a new amide, (8), and 19 known compounds were acquired from Melodorum siamensis, and seven showed nuclear factor-κB inhibitory effects in a pancreatic β cell line (MIN-6 cells).
Abstract: Four new chalcones (1, 10, 13, and 14), a new flavanone, (9), a new amide (8), and 19 known compounds were acquired from Melodorum siamensis. The structures were established by NMR and MS data analyses. Compounds 1 (er 1.4:1) and 2 (er 1.1:1) were scalemic and were resolved to yield (-)-1 and (+)-1 and (-)-2 and (+)-2, respectively. The absolute configurations of these compounds were determined from experimental and calculated ECD data. The structures and configurations of (-)-2 and (+)-8 were identified by single-crystal X-ray diffraction analysis. Compound 11 showed nuclear factor-κB inhibitory effects (IC50 = 9 μM) in a pancreatic β cell line (MIN-6 cells).
14 citations
TL;DR: Three new flavonoids: 5-hydroxy-7-(3-methyl-2,3-epoxybutoxy)flavanone,5-hydrox-3,8-dimethoxy 7-(3 methyl 2,3,epoxy-butoxy)-flavone and 4′-hydoxy-5-methoxy-7-methyl 2.3,3.epoxy butoxy (4.5 methyl 2.5 epoxy butoxide)flavinone were identified from the aerial parts of Achyrocline flacc
13 citations
TL;DR: In this article, two new flavanone glycosides 1 and 2 were isolated from the aerial parts of Macrothelypteris torresiana (Gaud.) Ching, and they were identified as (2 S )-5,7,2′,5′-tetrahydroxyflavanone-2.
13 citations
TL;DR: A series of novel flavonoids comprising structural elements present in the antineoplastic agents podophyllotoxin and etoposide was synthesized, finding that oxygen-containing analogues of antiproliferative quinolones moderate cytotoxicity towards L1210 and HT-29 cell lines.
Abstract: A series of novel flavonoids comprising structural elements present in the antineoplastic agents podophyllotoxin and etoposide was synthesized. These oxygen-containing analogues of antiproliferative quinolones exhibited moderate cytotoxicity towards L1210 and HT-29 cell lines.
13 citations