Topic
Flavanone
About: Flavanone is a research topic. Over the lifetime, 1965 publications have been published within this topic receiving 54729 citations. The topic is also known as: flavanones.
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TL;DR: Three new flavanone glucosides, myrciacitrins III, IV, and V, were isolated from the leaves of Brazilian Myrcia multiflora and were found to show potent inhibitory activity on aldose reductase.
Abstract: Following the characterization of myrciacitrins I and II and myrciaphenones A and B, three new flavanone glucosides, myrciacitrins III, IV, and V, were isolated from the leaves of Brazilian Myrcia multiflora. The structures of new myrciacitrins were elucidated on the basis of physicochemical and chemical evidence. Myrciacitrins were found to show potent inhibitory activity on aldose reductase.
93 citations
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TL;DR: Hesperidin, the most important flavanone of Citrus sp.
Abstract: Hesperidin, the most important flavanone of Citrus sp, obtained from the solid residue of orange peel, showed antihypertensive and diuretic effects on normotensive rats and on spontaneously hypertensive rats (SHR)
92 citations
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TL;DR: In this paper, the effects of two polyphenolic flavonoids (flavanone naringenin and flavonol quercetin) on development, fecundity, and mortality of Acyrthosiphon pisum Harris (Hemiptera: Aphididae) were determined in vitro, on an artificial diets.
Abstract: The effects of two polyphenolic flavonoids (flavanone naringenin and flavonol quercetin) on development, fecundity, and mortality of the pea aphid, Acyrthosiphon pisum Harris (Hemiptera: Aphididae), were determined in vitro, on an artificial diets. Also determined in vitro (DC EPG method), on sucrose–agarose gels, were the effects of flavonoids on the probing and feeding behavior of adult apterae. When added to a liquid diet, higher concentrations of studied flavonoids increased the developmental time, the pre-reproductive period, and mortality and decreased fecundity and the intrinsic rate of natural increase of A. pisum. In most events associated with stylet activity (as indicated by EPG waveform g-C), differences in probing behavior did not statistically differ between the control gel and those with flavonoids; quercetin at 10, 100, and 1,000 µg cm−3 prolonged the number of gel penetrations; and quercetin only at 10,000 μg cm−3 prolonged the time the first g-C waveform was observed. Addition of flavonoids to the gels generally reduced passive ingestion from fluids of the gels (EPG waveform g-E2). At higher concentrations (>1,000 µg cm−3) the flavonoids completely stopped salivation (EPG waveform g-E1) and passive ingestion from fluids of the gels (EPG waveform g-E2). In events associated with active ingestion (EPG waveform g-G), however, differences in feeding behavior did not statistically differ between the control gel and those with flavonoids. The present findings demonstrate detrimental effects of the flavanone naringenin and flavonol on the behavior of the pea aphid. This can be employed in a biotechnological projects for plant breeding resistant to herbivores, including aphids.
90 citations
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TL;DR: A new reaction mechanism, hydroxylation associated with 1,2‐migration, is proposed for the oxidative rearrangement reaction catalyzed by the cytochrome P‐450 enzyme of Pueraria lobata.
90 citations
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TL;DR: Two new flavanone glucosides, (2R)- and (2S)-5-O-beta-D-glucopyranosyl-7,4'-dihydroxy-3',5'-dimethoxyflavanone[pervianoside I (3), peruvianoside II(4)] and a new flavonol glycoside, quercetin 3-O-[alpha-L-rhamnopyranoyl
Abstract: Two new flavanone glucosides, (2R)- and (2S)-5-O-β-D-glucopyranosyl-7,4′-dihydroxy-3′,5′-dimethoxyflavanone[pervianoside I (3), peruvianoside II (4)] and a new flavonol glycoside, quercetin 3-O-{β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranoside} (peruvianoside III, 13) were isolated from the leaves of Thevetia peruviana SCHUM., together with nine known flavonol glycosides and two known iridoid glucosides. The structures of all compounds were determined on the basis of chemical and spectroscopic methods. Their inhibitory effects against HIV-1 reverse transcriptase and HIV-1 integrase were also investigated.
90 citations