scispace - formally typeset
Search or ask a question

Showing papers on "Fluorenone published in 1968"


Patent
30 Dec 1968
TL;DR: NOVEL BIS-BASIC ETHERS and THIOETHERS of FLUORENONE were selected from a base of the formulae DI(X-Y-)FLUORENE.
Abstract: NOVEL BIS-BASIC ETHERS AND THIOETHERS OF FLUORENONE, FLUORENOL AND FLUORENE SELECTED FROM A BASE OF THE FORMULA DI(X-Y-)FLUORENE WHEREIN: Z IS OXYGEN, H2 OF H,OH; EACH Y IS OXYGEN OR SULFUR; AND EACH X IS (A) THE GROUP -A-N(-R1)-R WHEREIN A IS ALKYLENE OF 2 TO ABOUT 8 CARBON ATOMS AND SEPARATES THE AMINO NITROGEN THEREOF AND Y BY AN ALKYLENE CHAIN OF AT LEAST 2 CARBON ATOMS, EACH R AND R1 IS HYDROGEN, (LOWER) ALKYL, CYCLOALKYL OF 3 TO 6 RING CARBON ATOMS, ALKENYL OF 3 TO 6 CARBON ATOMS HAVING THE VINYL UNSUTURATION IN OTHER THAN THE 1-POSITION OF THE ALKENYL GROUP, OR EACH SET OF R AND R1 TAKEN TOGETHER WITH THE NITROGEN TO WHICH THEY ARE ATTACHED IS PYRROLIDINO, PIPERIDINO, N(LOWER) ALKYLPIPERZINO, OR MOROPHOLIONO; OR EACH X IS (B) THE GROUP CH2<(-N(-R2)-(CH2)M-CH2-CH2)(-(CH2)N-) WHEREIN N IS A INTEGER OF 0 TO 2, M IS 1 OR 2 AND R2 IS HYDROGEN, (LOWER) AKLYL, OR ALKENYL OR 3 TO 6 CARBON ATOMS HAVING THE VINYL UNSATURATION IN OTHER THAN THE 1-POSITION OF THE ALKENYL GROUP; OR A PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT OF SAID BASE. THESE COMPOUNDS CAN BE USED AS PHARMACEUTICALS FOR PREVENTING OR INHIBITING A VIRAL INFECTION

22 citations



Journal ArticleDOI
TL;DR: Fluorenone and benzophenone oxime react in glacial acetic acid with lead tetraacetate to give parent ketones, geminal dinitromethanes, iminyl ketal derivatives (9,9-difluorenylideniminoxylfluorene...
Abstract: Fluorenone and benzophenone oxime react in glacial acetic acid with lead tetraacetate to give parent ketones, geminal dinitromethanes, iminyl ketal derivatives (9,9-difluorenylideniminoxylfluorene ...

7 citations


Patent
11 Oct 1968
TL;DR: In this paper, the authors present a list of the most important areas in a base of the formulae 9 (X=),BIS(R3-N(R2)-A-N(-R1)-CO-) FLUORENE where each region can be used as ANTI-INFECTIVE or ANTIMICROBIAL AGENTS.
Abstract: NOVEL COMPOUNDS SELECTED FROM A BASE OF THE FORMULA 9-(X=),BIS(R3-N(-R2)-A-N(-R1)-CO-)FLUORENE WHEREIN: X IS 0; H2; OR H,OH; EACH R1 IS HYDROGEN OR LOWER ALKYL; EACH A IS ALKYLENE OF 2 TO ABOUT 8 CARBON ATOMS AND SEPARATES ITS ADJACENT NITROGEN ATOMS BY AN ALKYLENE CHAIN OF AT LEAST 2 CARBON ATOMS; AND EACH R2 AND R3 IS HYDROGEN, LOWER ALKYL, CYCLOALKYL HAVING 3 TO ABOUT 6 RING CARBON ATOMS, ALKENYL OF 3 TO 6 CARBON ATOMS HAVING THE VINYL UNSATURATION IN OTHER THAN THE 1POSITON OF THE ALKENYL GROUP, OR EACH SET OF R2 AND R3 TAKEN TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE ATTACHED IS A SATURATED MONOCYCLIC HETEROCYCLIC GROUP HAVING 4 OR 5 RING CARBON ATOMS IN SAID HETEROCYCLIC GROUP; OR AN ACID ADDITION SALT OF SAID BASE. THE COMPOUNDS CAN BE USED AS ANTI-INFECTIVE OR ANTIMICROBIAL AGENTS, SUCH AS ANTIVIRAL, ANTIBACTERIAL AND ANTIFUNGAL AGENTS.

7 citations


Patent
23 Feb 1968
TL;DR: The class of OXAZOLONE DERIVATIVES and butenolide DERVATIVES of FLUORENONE are used as sensors for ORGANIC PHOTOCONDUCTIVE MEDIA as mentioned in this paper.
Abstract: THE COMPOUNDS ARE OF THE CLASS OF OXAZOLONE DERIVATIVES AND BUTENOLIDE DERIVATIVES OF FLUORENONE USEFUL AS SENSITIZERS FOR ORGANIC PHOTOCONDUCTIVE MEDIA. AN EXAMPLE OF A PARTICULAR SPECIES IS 2-PHENYL-4(2,4,7-TRINITRO-9-FLUORENYLIDENE)-5-OXAZOLONE.

6 citations


Journal ArticleDOI
TL;DR: 3,4-Benzocoumarins were obtained by oxidative cyclisation of biphenyl-2-carboxylic acids as mentioned in this paper, and the mechanisms of these reactions are discussed.
Abstract: 3,4-Benzocoumarins were obtained by oxidative cyclisation of biphenyl-2-carboxylic acids. The parent benzocoumarin was also formed by oxidation of 2′-substituted acids with elimination of the substituent (OMe, NO2, and CO2H and in low yield Me and Cl) but 2′-benzoylbiphenyl-2-carboxylic acid gave 5-benzoyl-3,4-benzocoumarin and 2′-cyanobiphenyl-2-carboxylic acid yielded fluorenone and phenanthridine-1,10-carbolactone. Similar oxidations of cis-cinnamic acids gave poor yields of coumarins, markedly increased by the presence of an o-methoxy-group. The mechanisms of these reactions are discussed.

5 citations


Journal ArticleDOI
TL;DR: In this paper, a concerted cyclic mechanism is proposed for the formation of 3-phenylphthalide as the sole product of the oxidation of o-benzylbenzoic acid.
Abstract: Oxidation of o-benzoylbenzoic acid with lead tetra-acetate in benzene solution under nitrogen affords benzophenone, o-phenylbenzophenone, and fluorenone as major products. Their formation is readily explicable by the the formation of o-benzoylphenyl radicals. The decomposition of intermediate lead (IV) salts by way of a concerted cyclic mechanism is suggested for the formation of 3-phenylphthalide as the sole product of the oxidation of o-benzylbenzoic acid.

4 citations


Journal ArticleDOI
TL;DR: In this paper, the rates of the sodium borohydride reduction of some 3-substituted fluorenones in anhydrous isopropyl alcohol, and of the perchloric acid-catalysed solvolysis of 9-diazofluorenes in 93·8 % w/w ethanol-water have been determined.
Abstract: The rates of the sodium borohydride reduction of some 3-substituted fluorenones in anhydrous isopropyl alcohol, and of the perchloric acid-catalysed solvolysis of some 3-substituted 9-diazofluorenes in 93·8 % w/w ethanol–water have been determined. The former reaction is hindered by electron-releasing groups and facilitated by electron withdrawal, whilst for the latter process the opposite is true. In both series the well known compensating relationship between the energies and entropies of activation is found.Treatment of the data by Hammett type equations indicates that, for the 9-diazofluorene series, the extent of transmission of T effects to the 9-position is essentially that which would be expected for a normal para-position, whereas, for the fluorenone series, resonance effects are slightly but significantly smaller. This result is discussed in terms of possible loss of conjugation in the transition state and differences in aromaticity of the central five-membered ring.The results for both series agree satisfactorily with the predictions of molecular orbital calculations, and a simple relationship between the theoretical quantities and the extent of operation of resonance effects is developed which is shown to hold for substituents in the 2-, 3-, and 4-positions.

2 citations