Topic
Friend leukemia
About: Friend leukemia is a research topic. Over the lifetime, 319 publications have been published within this topic receiving 7463 citations.
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TL;DR: There is a three- to four-fold decrease in the content/cell of tRNAs for ten different amino acids four days after the induction of erythroid differentiation in Friend leukemia cells, consistent with the decrease in cell volume that occurs.
2 citations
2 citations
TL;DR: Fli-1 regulates multiple biological functions in different cancers particularly Ewing sarcoma and leukemias as mentioned in this paper, and there are controversial reports regarding function and prognostic significance of Fli-1...
Abstract: Fli-1 regulates multiple biological functions in different cancers particularly Ewing sarcoma and leukemias. There are controversial reports regarding function and prognostic significance of Fli-1 ...
2 citations
TL;DR: All Friend leukemia cell lines induced by polycythemic strains of Friend leukemia virus complex express an appreciable amount of spleen focus-forming virus (SFFV)-coding envelope gene (env)-related glycoprotein with a molecular weight of 55 kilodaltons (gp55).
Abstract: All Friend leukemia cell lines induced by polycythemic strains of Friend leukemia virus complex express an appreciable amount of spleen focus-forming virus (SFFV)-coding envelope gene (env)-related glycoprotein with a molecular weight of 55 kilodaltons (gp55). A clonal, highly differentiation-inducible Friend leukemia cell line, T3-C1-2-O(2-O), possesses not only gp55 but also gp51 as SFFV-specific gene products. The peptide map of gp51 is quite similar to that of gp55 and the difference in their molecular weights is primarily dependent on their oligosaccharide content. In the differentiation-induced state, gp51 becomes far less detectable than gp55 in 2-O cells. The biological significance of this novel SFFV-coding glycoprotein is discussed.
2 citations