Topic
Fundus (eye)
About: Fundus (eye) is a research topic. Over the lifetime, 8265 publications have been published within this topic receiving 145317 citations. The topic is also known as: Fundus Oculi.
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TL;DR: A common detection and classification system is needed for epidemiologic studies of age-related maculopathy (ARM) and such a grading scheme for ARM is described in this paper.
1,871 citations
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TL;DR: In this paper, a method to obtain images of the choroid using conventional spectral-domain optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images was described.
1,759 citations
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TL;DR: Optical coherence tomography is potentially a powerful tool for detecting and monitoring a variety of macular diseases, including macular edema, macular holes, and detachments of the neurosensory retina and pigment epithelium.
1,278 citations
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TL;DR: Methods for 2-D fundus imaging and techniques for 3-D optical coherence tomography (OCT) imaging are reviewed and aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships.
Abstract: Many important eye diseases as well as systemic diseases manifest themselves in the retina. While a number of other anatomical structures contribute to the process of vision, this review focuses on retinal imaging and image analysis. Following a brief overview of the most prevalent causes of blindness in the industrialized world that includes age-related macular degeneration, diabetic retinopathy, and glaucoma, the review is devoted to retinal imaging and image analysis methods and their clinical implications. Methods for 2-D fundus imaging and techniques for 3-D optical coherence tomography (OCT) imaging are reviewed. Special attention is given to quantitative techniques for analysis of fundus photographs with a focus on clinically relevant assessment of retinal vasculature, identification of retinal lesions, assessment of optic nerve head (ONH) shape, building retinal atlases, and to automated methods for population screening for retinal diseases. A separate section is devoted to 3-D analysis of OCT images, describing methods for segmentation and analysis of retinal layers, retinal vasculature, and 2-D/3-D detection of symptomatic exudate-associated derangements, as well as to OCT-based analysis of ONH morphology and shape. Throughout the paper, aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships.
1,118 citations
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TL;DR: Protocols have been developed for nonmydriatic fundus photography and for evaluation of retinal vascular abnormalities in the ARIC Study and several microvascular changes were significantly associated with higher blood pressure, controlling for gender, race, age, and smoking status.
1,112 citations