Showing papers on "genomic DNA published in 1969"
TL;DR: Two molecular models of chromosome structure which have recently been put forward are consistent with observations and account for many cytogenetic, genetic and ultrastructural phenomena.
Abstract: IN all eukaryotic organisms so far investigated, the genomic DNA includes reiterated DNA sequences which are referred to as families of related base sequences1, and two molecular models of chromosome structure which have recently been put forward are consistent with these observations. Callan7's master–slave hypothesis2 has it that certain regions of the chromosomal DNA, especially those of the lateral loops of lampbrush chromosomes, are sequential reiterations of functionally equivalent gene sequences. Similarly, Beermann3 has proposed that the chromomere of the chromosome is a repository for families of similar but not necessarily identical genes. These models account for many cytogenetic, genetic and ultrastructural phenomena.
39 citations
TL;DR: Chromosomal RNA, which is associated with chromosomal proteins in the chromosomes of higher organisms, possess the ability to hybridize to homologous native DNA, and both proportions are similar to the proportions of chromosomal RNA and DNA in native chromatin.
Abstract: Chromosomal RNA, which is associated with chromosomal proteins in the chromosomes of higher organisms, possess the ability to hybridize to homologous native DNA. The proportion of native DNA thus hybridized is similar to the proportion of denatured DNA which hybridizes with chromosomal RNA, and both are similar to the proportions of chromosomal RNA and DNA in native chromatin.
32 citations