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Glucose Measurement

About: Glucose Measurement is a research topic. Over the lifetime, 1409 publications have been published within this topic receiving 37869 citations.


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Patent
17 Jan 1990
TL;DR: In this article, a method for custom calibrating near-infrared quantitative analysis instruments including obtaining a plurality of blood samples and blood glucose level measurements thereof at a predetermined time interval is presented.
Abstract: Near-infrared quantitative analysis instruments (170) non-invasively measure blood glucose by analyzing near-infrared energy following interactance with venous or arterial blood, or transmission through a blood containing body part. A replaceable cartridge (195) stores data unique to an individual patient/user. The analysis instruments (170) are accurate and readily lend themselves to at-home testidiabetics. A method is also disclosed for easily and reliably custom calibrating near-infrared quantitative analysis instruments including obtaining a plurality of blood samples and blood glucose level measurements thereof at a predetermined time interval. These values are entered into the analysis instrument. Near-infrared optical measurements of the individual are simultaneously taken using the analysis instrument at another predetermined time interval. Calibration regression analysis is performed on the data to custom calibrate the analysis instrument which involves linearly interpolating the blood sample glucose measurements with the near-infrared optical recordings.

578 citations

Journal ArticleDOI
TL;DR: Interstitial glucose measurements with the FreeStyle Libre system were found to be accurate compared with capillary BG reference values, with accuracy remaining stable over 14 days of wear and unaffected by patient characteristics.
Abstract: Introduction: The purpose of the study was to evaluate the performance and usability of the FreeStyle® Libre™ Flash glucose monitoring system (Abbott Diabetes Care, Alameda, CA) for interstitial glucose results compared with capillary blood glucose results. Materials and Methods: Seventy-two study participants with type 1 or type 2 diabetes were enrolled by four U.S. clinical sites. A sensor was inserted on the back of each upper arm for up to 14 days. Three factory-only calibrated sensor lots were used in the study. Sensor glucose measurements were compared with capillary blood glucose (BG) results (approximately eight per day) obtained using the BG meter built into the reader (BG reference) and with the YSI analyzer (Yellow Springs Instrument, Yellow Springs, OH) reference tests at three clinic visits (32 samples per visit). Sensor readings were masked to the participants. Results: The accuracy of the results was demonstrated against capillary BG reference values, with 86.7% of sensor results w...

540 citations

Journal ArticleDOI
TL;DR: This article reviews many of the recent advances in optical glucose sensing including optical absorption spectroscopy, polarimetry, Raman spectroscopes, and fluorescent glucose sensing and a review of calibration and data processing methods useful for optical techniques is presented.
Abstract: Recent technological advancements in the photonics industry have led to a resurgence of interest in optical glucose sensing and to realistic progress toward the development of an optical glucose sensor Such a sensor has the potential to significantly improve the quality of life for the estimated 16 million diabetics in this country by making routine glucose measurements more convenient Currently over 100 small companies and universities are working to develop noninvasive or minimally invasive glucose sensing technologies, and optical methods play a large role in these efforts This article reviews many of the recent advances in optical glucose sensing including optical absorption spectroscopy, polarimetry, Raman spectroscopy, and fluorescent glucose sensing In addition a review of calibration and data processing methods useful for optical techniques is presented

433 citations

Journal ArticleDOI
TL;DR: Invasive and noninvasive blood glucose monitoring methods using various biofluids or blood are described, highlighting the recent progress in the development of enzyme‐based glucose sensors and their integrated systems.
Abstract: Blood glucose concentration is a key indicator of patients' health, particularly for symptoms associated with diabetes mellitus. Because of the large number of diabetic patients, many approaches for glucose measurement have been studied to enable continuous and accurate glucose level monitoring. Among them, electrochemical analysis is prominent because it is simple and quantitative. This technology has been incorporated into commercialized and research-level devices from simple test strips to wearable devices and implantable systems. Although directly monitoring blood glucose assures accurate information, the invasive needle-pinching step to collect blood often results in patients (particularly young patients) being reluctant to adopt the process. An implantable glucose sensor may avoid the burden of repeated blood collections, but it is quite invasive and requires periodic replacement of the sensor owing to biofouling and its short lifetime. Therefore, noninvasive methods to estimate blood glucose levels from tears, saliva, interstitial fluid (ISF), and sweat are currently being studied. This review discusses the evolution of enzyme-based electrochemical glucose sensors, including materials, device structures, fabrication processes, and system engineering. Furthermore, invasive and noninvasive blood glucose monitoring methods using various biofluids or blood are described, highlighting the recent progress in the development of enzyme-based glucose sensors and their integrated systems.

420 citations

Patent
29 Jul 2008
TL;DR: In this paper, a system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensors and calibrates the data streams using a single point glucose monitor that is integral with the integrated receiver.
Abstract: A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

401 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202154
202056
201972
201879
201761
201669