Topic
Glucoside
About: Glucoside is a research topic. Over the lifetime, 3183 publications have been published within this topic receiving 56075 citations. The topic is also known as: glucosides.
Papers published on a yearly basis
Papers
More filters
TL;DR: It is suggested that quercetin glucoside is actively absorbed from the small intestine, whereas quercettin rutinoside is absorbed fromThe colon after deglycosylation, suggesting that Absorption of other food components might also be enhanced by attachment of a glucose group.
Abstract: Flavonoids are antioxidants present in plant foods. They occur mainly as glycosides, i.e. linked with various sugars. It is uncertain to what extent dietary flavonoid glycosides are absorbed from the gut. We investigated how the nature of the sugar group affected absorption of one major flavonoid, quercetin. Quercetin linked with glucose, i.e. quercetin glucoside and quercetin linked with rutinose, i.e. quercetin rutinoside, both occur widely in foods. When we fed these compounds to nine volunteers, the peak concentration of quercetin (Cmax) in plasma was 20 times higher and was reached (Tmax) more than ten times faster after intake of the glucoside (Cmax = 3.5 ± 0.6 μM (mean ± SE); Tmax < 0.5 h) than after the rutinoside (Cmax = 0.18 ± 0.04 μM; Tmax = 6.0 ± 1.2 h). The bioavailability of the rutinoside was only 20% of that of the glucoside. We suggest that quercetin glucoside is actively absorbed from the small intestine, whereas quercetin rutinoside is absorbed from the colon after deglycosylation. Abso...
507 citations
Patent•
15 May 2003TL;DR: In this article, an SGLT2 inhibiting compound is provided having the formula having the chemical structure, and a method is also provided for treating diabetes and related diseases employing an sGLT 2 inhibiting amount of the above compound alone or in combination with another antidiabetic agent or other therapeutic agent.
Abstract: An SGLT2 inhibiting compound is provided having the formula[Chemical structure] A method is also provided for treating diabetes and related diseases employing an SGLT2 inhibiting amount of the above compound alone or in combination with another antidiabetic agent or other therapeutic agent.
327 citations
TL;DR: In this paper, the phenolic compounds present in 29 samples of olive fruits were analysed by reversed-phase HPLC/DAD and/or HPLC-DAD/ESI-MS/MS.
313 citations
TL;DR: The apparent bioavailability of genistein and daidzein is not different when consumed as either aglycone or glucoside by American women, probably because of the metabolic action of intestinal bacteria during the long intestinal transit time of glucosides.
307 citations
TL;DR: The surface tension in aqueous solutions of β-Dalkyl glucoside and their mixtures at 25°C has been measured in this article, and the effect of added salts on the CMC was determined from the inflexions of the surface tension vs. logarithm of concentration curves.
Abstract: The surface tension in aqueous solutions of β-D-alkyl glucoside and their mixtures at 25°C has been measured. The CMC was determined from the inflexions of the curves; octyl glucoside, 0.025 mol./1., decyl glucoside 0.0022 mol./1., dodecyl glucoside, 0.00019 mol./1. The effect of hydrocarbon chain length was explained theoretically. The CMC of mixtures has been also explained by the extension of the theory of ionic agents. The effect of added sodium chloride, calcium chloride and sodium sulfate on the surface tension in aqueous solution of octyl glucoside has been measured. The effect of added salts on the CMC was determined from the inflexions of the surface tension vs. logarithm of concentration curves.
296 citations