Showing papers on "Glucoside published in 1978"
TL;DR: Aloenin, a new bitter glucoside with an inhibitory activity for the gastric juice secretion of rats, was isolated from the leaves of Aloe arborescens mill. var. natalensis Berger as discussed by the authors.
Abstract: Aloenin, a new bitter glucoside with an inhibitory activity for the gastric juice secretion of rats, was isolated from the leaves of Aloe arborescens Mill. var. natalensis Berger, and the structure...
41 citations
TL;DR: From fresh Pinus contorta Doug (Coastal) needles four flavonol acylated glucosides and 6-methyl-kaempferol 3β-D -glucoside were isolated as mentioned in this paper.
41 citations
TL;DR: The enzyme had MW 65 000 daltons, pH optimum at 5.2-5.6, and was solubilized by acetone treatment as mentioned in this paper, with an about 1500 times higher specific activity with respect to the crude homogenate.
27 citations
27 citations
TL;DR: Evidence indicates that steryl glucosides and their acylated derivatives were synthesized by algae, and the early assumption that these compounds were not present in algae must be revised.
22 citations
21 citations
TL;DR: In this article, it was suggested that the capacity for glucosylation of cytokinin bases increases during expansion and maturation of the leaf, and more 14C-labelled glucoside was produced in mature, than in immature leaves.
18 citations
TL;DR: Two classes of glucoside esrters can be distinguished: those with a shosrtchain fattyacid part (C14 to C20), devopid of toxicitgy and affectomg pxodfatove phosphorylzation at both coupling II and III;ester of the C32-branched chain acid exhibniting toxicity in vivo and specific inhibnition of oxidative phosphorylation at coupling site II in vitro.
Abstract: 6-Monoesters of methyl α-D-glucopyranoside and the even-numbered normal chain fatty acids C14toC22 or 2-tetradecyloctadecanoic acid (DL-deoxy-corynomycolic acid) have been prepared. All the normal chain fatty acid esters were devoid of toxicity for mice at the dose of 2 mg per animal, whereas the branched chain ester (deoxy-corynomycolate) exhibited a low, bnut characteristic, toxicity.
Preincubation of rat liver mitochondria with aqueous suspensions of these synthetic esters gave the following results. The shorter chain (C14 to C20) esters affected the mitochondrial respiration and coupled phosphorylation in both succinate and NADH pathways at both coupling sites II and III. The same effects were obtained by using methyl 2-hexad3ecanoyl-α-D-glucopyranoside or 6-hexadecanoyl-l-asorbic acid, showing that the position of the ester linkage on the sugar residue or the conformation of the sugar moiety are not essential. Deoxycorynomyucolate induced an impairmant of mitochondrial oxidative phosphoryl;ation mainly localized at couplilng site II. Methyl 6-do-cosanoyl and 2,6-sisoxoanoyl α-D-glucopyranosides affected only coupling site II. Inbtroductionof a double bnonmd in the fattyacid chain (docos-13-cis-enote) gave results similar to those obtained with shorter chain esters.
Two classes of glucoside esrters can thus be distinguished: those with a shosrtchain fattyacid part (C14 to C20), devopid of toxicitgy and affectomg pxodfatove phosphorylzation at both coupling II and III;ester of the C32-branched chain acid exhibniting toxicity in vivo and specific inhibnition of oxidative phosphorylation at coupling site IIin vitro. Mono and diesters of docosanoic acid have an intermediate position (no toxicity, but a specific effect on mitochondria)
The absence of toxicity of the short cahin ester (C14 to C22)seems to be expplained by their neutralization bty serum albumin.
18 citations
17 citations
TL;DR: The observations suggest that acyl donors other than digalactosyl diglyceride and phospholipids may function in steryl acyl glucoside synthesis in plants.
16 citations
TL;DR: Potato tuber α-glucosidase has an isoelectric point of 4.7 and an apparent MW of 120 000 as discussed by the authors, and has a neutral pH optimum (pH 6.5-7.0) and a Km of 0.21 mM for p-nitrophenol-α- D -glucose at pH 6.8 and 30°.
02 Nov 1978
TL;DR: Campestroside has been isolated from the aerial parts of Gentiana campestris and its structure has been established as 1,3,5-trihydroxy-8-β- d -glucopyranosyl-5,6,7,8-tetrahydroxanthone.
TL;DR: In this article, the authors used a vacuum infiltration technique to sample 4-hydroxyphenoxy acetic acid (4-OH-POA) and its phenolic glucoside (OGlu-POAs) in a segment of Avena and Pisum.
Abstract: The metabolism of phenoxyacetic acid (POA) was followed over short periods in segments of Avena and Pisum using a vacuum infiltration technique. Both species form 4-hydroxyphenoxy acetic acid (4-OH-POA) and its phenolic glucoside (OGlu-POA) but Pisum incorporates much of the substrate into an insoluble wall component. This insoluble material appears to be formed from 4-OH-POA. Preliminary kinetic experiments show that the overall conversion of POA is linearly related to concentration up to 2 /?mol POA g-1 fresh tissue and can be completed in a few hours. The method provides a very useful means of preparing sufficient quantities of '"C-labelled 4-OH POA and OGlu-POA in a pure form for subsequent use as substrates for the enzymes involved in glucosylation and formation of the insoluble material. Although light has relatively little effect on hydroxylation, the capacity for formation of both the glucoside and the insoluble material is increased by continuous fluorescent, red, and far red light. The results so far obtained suggest that phytochrome is involved in the transformations. The chlorinated derivatives of phenoxyacetic acid with high herbicidal activity e.g. 2,4-dichloro phenoxyacetic acid (2,4-D) are also metabolized by analogous reactions and the formation of hydroxylated and glycosylated derivatives may contribute to the detoxification of such herbicides in resistant species.
TL;DR: A triterpene glucoside, cymbidoside as mentioned in this paper, has been isolated from Cymbidium giganteum and its structure is shown to be 4ξ-(β- d -glucopyranosyloxymethyl)-14α-methyl-22ξ, 24ξ and 25,28-tetrahydroxy-9,19-cyclo-5α,9β-ergostan-3-one.
01 Jan 1978
TL;DR: The method provides a very useful means of preparing sufficient quantities of '"C-labelled 4-OH POA and OGlu-POA in a pure form for subsequent use as substrates for the enzymes involved in glucosylation and formation of the insoluble material".
Abstract: The metabolism of phenoxyacetic acid (POA) was followed over short periods in segments of Avena and Pisum using a vacuum infiltration technique. Both species form 4-hydroxyphenoxy acetic acid (4-OH-POA) and its phenolic glucoside (OGlu-POA) but Pisum incorporates much of the substrate into an insoluble wall component. This insoluble material appears to be formed from 4-OH-POA. Preliminary kinetic experiments show that the overall conversion of POA is linearly related to concentration up to 2 /?mol POA g-1 fresh tissue and can be completed in a few hours. The method provides a very useful means of preparing sufficient quantities of '"C-labelled 4-OH POA and OGlu-POA in a pure form for subsequent use as substrates for the enzymes involved in glucosylation and formation of the insoluble material. Although light has relatively little effect on hydroxylation, the capacity for formation of both the glucoside and the insoluble material is increased by continuous fluorescent, red, and far red light. The results so far obtained suggest that phytochrome is involved in the transformations. The chlorinated derivatives of phenoxyacetic acid with high herbicidal activity e.g. 2,4-dichloro phenoxyacetic acid (2,4-D) are also metabolized by analogous reactions and the formation of hydroxylated and glycosylated derivatives may contribute to the detoxification of such herbicides in resistant species.
TL;DR: The glucosides of stigmasterol, sitosterol and cholesterol displayed auxin-like activity in the Avena coleoptile test and enhanced the growth promoting activity of IAA and no synergistic or antagonistic effects of the test compounds were recorded with gibberellic acid or cytokinin.
TL;DR: Aloenin, a new bitter glucoside with an inhibitory activity for the gastric juice secretion of rats, was isolated from the leaves of Aloe arborescens mill. var. natalensis Berger.
Abstract: Aloenin, a new bitter glucoside with an inhibitory activity for the gastric juice secretion of rats, was isolated from the leaves of Aloe arborescens Mill. var. natalensis Berger, and the structure...
TL;DR: Cell suspension cultures of some 12 plants were investigated for anthranilic acid metabolism and found rapid uptake of substrate is accompanied by partial excretion of anthranobic acid-N-glucoside and followed by predominant conversion into tryptophan.
Abstract: Abstract Cell suspension cultures of some 12 plants were investigated for anthranilic acid metabolism. Rapid uptake of substrate is accompanied by partial excretion of anthranilic acid-N-glucoside and followed by predominant conversion into tryptophan. Ring cleavage reactions of anthranilate could not be observed but peroxidatic polymerisation occurred to a high percentage. Anthranilic acid-N-glucoside is not permanently stored by the cell cultures.
Patent•
08 Nov 1978
TL;DR: The effectiveness of herbicides in general is enhanced, or boosted, by using them in combination with the glucoside, fusicoccyn as discussed by the authors, which can be found in many herbicides.
Abstract: The effectiveness of herbicides in general is enhanced, or boosted, by using them in combination with the glucoside, fusicoccyn.
Patent•
09 Mar 1978
TL;DR: In this article, an effective ingredient mandelic acid glucoside having high carcinostatic activity with reduced toxicity and no side effects was used to prepare anticancerous preparations, which can be administered orally.
Abstract: PURPOSE:To prepare anticancerous preparations, which can be administered orally, comprising as an effective ingredient mandelic acid glucoside having high carcinostatic activity with reduced toxicity and no side effects.