Topic
Glycal
About: Glycal is a research topic. Over the lifetime, 897 publications have been published within this topic receiving 17422 citations.
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22 Jan 2019
TL;DR: In this article, 2-Deoxy-α-glycosides of oleonane type triterpene alcohols and deoxycholic acid were synthesized by glycosylation with glycal acetates in the presence of iodonium dicollidine perchlorate followed by deiodination and deprotection.
Abstract: 2-Deoxy-α-glycosides of oleonane type triterpene alcohols and deoxycholic acid were synthesized by glycosylation with glycal acetates in the presence of iodonium dicollidine perchlorate followed by deiodination and deprotection.
TL;DR: In this paper, the Ireland-Claisen rearrangement of the allyl ester 5 and a stereoselective epoxidation of the furanoid glycal 12 with 2,2-dimethyldioxirane were used to synthesize the squalestatins and zaragozic acids.
Abstract: A synthesis of a model core system ( 18 ) of the squalestatins and zaragozic acids has been achieved from D-mannose. The key steps involve an Ireland-Claisen rearrangement of the allyl ester 5 and a stereoselective epoxidation of the furanoid glycal 12 with 2,2-dimethyldioxirane.
TL;DR: In this paper, the preparation of a conjugated pyranoid vinyl glycal along with several of its thermal [4+2] cycloaddition reactions with a variety of dienophiles are discussed.
Abstract: The preparation of a conjugated pyranoid vinyl glycal is reported, along with several of its thermal [4+2] cycloaddition reactions with a variety of dienophiles. Applications to the anthraquinone antitumor agents are discussed.