Topic
Glycal
About: Glycal is a research topic. Over the lifetime, 897 publications have been published within this topic receiving 17422 citations.
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TL;DR: In this article, a new spirocyclization was developed for the synthesis of 1,7-dioxaspiro[5.5]undecanes and 1-oxa-7-thiaspiro[ 5.5]-undecane by reaction of exo-glycal with aryl alcohols or thiophenols in the presence of Lewis acid BF 3 ·OEt 2.
Abstract: A new spirocyclization was developed for the synthesis of 1,7-dioxaspiro[5.5]undecanes and 1-oxa-7-thiaspiro[5.5]undecanes by reaction of exo -glycal with aryl alcohols or thiophenols in the presence of Lewis acid BF 3 ·OEt 2 . The reaction proceeded through tandem Ferrier rearrangement, glycosylation, and Friedel–Crafts alkylation to provide the corresponding products in good to excellent yields.
TL;DR: Palladium acetate catalyzed C -glycosidation of peracetylated glycals with arylboronic acids in acetonitrile (CH 3 CN) yields the desired 1-substituted 2,3-unsaturated glycal as well as a byproduct corresponding to the ring-opened pyran, present in varying proportions depending on the reaction conditions used as discussed by the authors.
Abstract: Palladium acetate catalyzed C -glycosidation of peracetylated glycals with arylboronic acids in acetonitrile (CH 3 CN) yields the desired 1-substituted 2,3-unsaturated glycal as well as a byproduct corresponding to the ring-opened pyran, present in varying proportions depending on the reaction conditions used. The byproduct is not formed when toluene/EtOH is used as reaction solvent.
TL;DR: In this article, 2-C -acetoxymethyl glycal derivatives react with aliphatic alcohols in the presence of InCl 3 to furnish the corresponding 2-c -methylene glycosides in excellent yields and with exclusive α-selectivity.
Abstract: 2- C -Acetoxymethyl glycal derivatives react with aliphatic alcohols in the presence of InCl 3 (30 mol %) to furnish the corresponding 2- C -methylene glycosides in excellent yields and with exclusive α-selectivity except for the methyl 2- C -methylene glycosides, which are formed in ∼2:1 anomeric ratio in favour of the α-anomer. The reaction of 2- C -acetoxyglycals with phenols, however, produces the corresponding chiral carbohydrate-derived pyranobenzopyran derivatives via initial Ferrier rearrangement followed by tandem cyclization in excellent yields and moderate to high stereoselectivities in favour of the corresponding 10a- R -pyrano[2,3- b ][1]benzopyran derivatives.
Patent•
03 Nov 2017
TL;DR: In this paper, a synergistic bactericide composition consisting of polyoxins and glucan glycal was proposed for preventing and treating alternaria leaf spot of apple trees and the like.
Abstract: The invention provides a synergistic bactericide composition, and a preparation method and application thereof The effective medicinal components of the composition consist of polyoxins and glucan glycal, wherein the weight ratio of the polyoxins to the glucan glycal is (5-10):(01-5); the synergistic bactericide composition is prepared by a mixing mode and can be applied to preparation of pesticide for preventing and treating alternaria leaf spot; and the polyoxins and the glucan glycal in the composition are compounded according to the specific proportion and are synergistic, so the effect of preventing and treating alternaria leaf spot of apple trees and the like is remarkable