Topic
Hamayne
About: Hamayne is a research topic. Over the lifetime, 21 publications have been published within this topic receiving 596 citations. The topic is also known as: hamayne & (+)-hamayne.
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TL;DR: Alkaloidal extracts of bulbs from each species showed inhibition of acetylcholinesterase, an activity exploited therapeutically to raise the depressed levels ofacetylcholine in the brain associated with Alzheimer's disease.
97 citations
TL;DR: A phytochemical investigation of the bulbs of Brunsvigia radulosa yielded the new alkaloid 1-O-acetylnorpluviine, together with the known structures 1-epideacetylbowdensine, crinamine, cr inine, hamayne, lycorine, anhydrolycorin-6-one and sternbergine, established by spectroscopic evidence.
83 citations
TL;DR: A new base, 3-O-acetylhamayne (11), was isolated from Crinum latifolium L. as discussed by the authors along with crinamine (3), powelline (4), crinine (5), hamayne (8), undulatine (13), and cherylline (14).
Abstract: A new base, 3-O-acetylhamayne (11), was isolated from Crinum latifolium L. (Amaryllidaceae) along with crinamine (3), powelline (4), crinine (5), 1-O-acetyllycorine (6), hamayne (8), undulatine (13), and cherylline (14). The bases 3, 4, 5, and 14, as well as diacetyllycorine (7), crinamidine (16), O-acetylcrinine (17), deacetylbowdensine (18), and bowdensine (19), were also isolated from Crinum bulbispermum MILNE-REDHEAD et SCHWEICKERDT (Amaryllidaceae).
53 citations
01 Jan 1992
TL;DR: Activity-directed fractionation of a Crinum jagus methanol extract gave four alkaloids, lycorine, hamayne, crinamine and 6-hydroxycrinamine, which showed strong antibacterial activity and neither the extracts nor the alkaloid possess any antifungal activity.
Abstract: Activity-directed fractionation of a Crinum jagus methanol extract used in traditional medicine as an antibacterial agent gave four alkaloids, lycorine, hamayne, crinamine and 6-hydroxycrinamine. Only crinamine showed strong antibacterial activity. Neither the extracts nor the alkaloids possess any antifungal activity.
51 citations
TL;DR: Six alkaloids, 3- O -acetylhamayne, hamayne, crinamine, josephinine, ambelline and stembergine have been isolated from bulbs of BrunsvigiaJosephinae (Amaryllidaceae) by physical and spectroscopic methods.
48 citations