Topic
Hemidesmus indicus
About: Hemidesmus indicus is a research topic. Over the lifetime, 301 publications have been published within this topic receiving 5305 citations. The topic is also known as: Indian sarsaparilla.
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TL;DR: Protective activity of plants-Aristolochia indica, Hemidesmus indicus, Gloriosa superba, Strychnos nux-vomica, Eclipta prostrata, and Andrographis paniculata against the lethal action of snake venom and need further investigation.
271 citations
TL;DR: The data indicated that Coscinium fenestratum had a strong inhibitory effect on Propionibacterium acnes and Staphylococcus epidermidis.
Abstract: Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. The present study was conducted to evaluate antimicrobial activities of Indian medicinal plants against these etiologic agents of acne vulgaris. Ethanolic extracts of Hemidesmus indicus (roots), Eclipta alba (fruits), Coscinium fenestratum (stems), Curcubito pepo (seeds), Tephrosia purpurea (roots), Mentha piperita (leaves), Pongamia pinnata (seeds), Symplocos racemosa (barks), Euphorbia hirta (roots), Tinospora cordyfolia (roots), Thespesia populnea (roots), and Jasminum officinale (flowers) were tested for antimicrobial activities by disc diffusion and broth dilution methods. The results from the disc diffusion method showed that 07 medicinal plants could inhibit the growth of Propionibacterium acnes. Among those Hemidesmus indicus, Coscinium fenestratum, Tephrosia purpurea, Euphorbia hirta, Symplocos racemosa, Curcubito pepo and Eclipta alba had strong inhibitory effects. Based on a broth dilution method, the Coscinium fenestratum extract had the greatest antimicrobial effect. The MIC values were the same (0.049 mg/ml) for both bacterial species and the MBC values were 0.049 and 0.165 mg/ml against Propionibacterium acnes and Staphylococcus epidermidis, respectively. In bioautography assay, the Coscinium fenestratum extract produced strong inhibition zones against Propionibacterium acnes. Phytochemical screening of Coscinium fenestratum revealed the presence of alkaloid which could be responsible for activity. Taken together, our data indicated that Coscinium fenestratum had a strong inhibitory effect on Propionibacterium acnes and Staphylococcus epidermidis.
219 citations
TL;DR: These herbs shows anti-inflammatory activity by suppressing the capacity of P. acnes-induced ROS and pro-inflammatory cytokines, the two important inflammatory mediators in acne pathogenesis.
142 citations
TL;DR: It is suggested that all the three plants possess larvicidal properties that could be developed and used as natural insecticides for mosquito control.
Abstract: The larvicidal effect of aqueous extracts of Hemidesmus indicus roots, Gymnema sylvestre and Eclipta prostrata leaves were tested against Culex quinquefasciatus larvae at the concentrations of 1, 2, 3, 4 and 5% up to three days. All extracts showed larval mortality. Larval mortality was 100% with the use of 5% concentration of root extract of H. indicus, leaves extracts of G. sylvestre and E. prostrata after 2 days. Qualitative analysis of the phytochemicals of aqueous extracts revealed the presence of carbohydrates, saponins, phytosterols, phenols, flavonoids and tannins in all the plants. Quantitative analysis showed that the crude saponin was the major phytochemical constituent present in highest percentage followed by crude tannin in all three plants. It is suggested that all the three plants possess larvicidal properties that could be developed and used as natural insecticides for mosquito control.
134 citations
TL;DR: The methanolic extract of H. indicus root bark was found to have different levels of antioxidant properties in the models tested, suggesting that the free radical scavenging property may be one of the mechanisms by which this drug is effective in several free radical mediated disease conditions.
132 citations