Showing papers on "Holothuria published in 2000"
TL;DR: 1 showed neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cell, and was the first report on the isolation and structure elucidation of trisialo-ganglioside from sea cucumber.
Abstract: A new ganglioside molecular species, HPG-7 (1) was obtained from the polar fraction of the chloroform/methanol extract of the sea cucumber, Holothuria pervicax. On the basis of chemical and spectroscopic evidence, the structure of 1 was determined, and the major component was 1-O-[alpha-L-fucopyranosyl-(1-->4)-(N-acetyl-alpha-D-neuraminosyl) - (2-->11)-(N-glycolyl-alpha-D-neuraminosyl)-(2-->4)-(N-acetyl -alpha-D- neuraminosyl)-(2-->6)-beta-D-glucopyranosyl]-(2S,3S,4R)-2-[(2R)-2- hydroxytetracosanoylamino]-14-methyl-hexadecane-1,3,4-triol. This is the first report on the isolation and structure elucidation of trisialo-ganglioside from sea cucumber. 1 showed neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cell.
30 citations
TL;DR: The importance of the Kiunga Marine National Reserve as a sanctuary in the conservation of the marine invertebrate fauna is stressed, based on the results of a field trip, and additional information from the literature.
Abstract: The echinoderm fauna of the Kiunga Marine National Reserve, Kenya, is documented, based on the results of a field trip, and additional information from the literature. In this first paper, the Holothuroidea and Echinoidea are discussed. A total of 91 specimens representing eight orders, 13 families, 19 genera and 37 species were collected. Five other species were not collected but were identified in the field. Six additional species are reported from literature only and are not discussed. Diagnostic characters of every species recorded are given, as well as an assessment of their abundance in the Kiunga Marine Reserve. Clypeaster rarispinus, Phyllacanthus imperialis, Microcyphus rousseaui (Echinoidea), Holothuria (Cystipus) rigida, Holothuria (Platyperona) difficilis, Labidodemas pertinax, Stichopus chloronotus and Stichopus cf. monotuberculatus (Holothuroidea) are new records for Kenya. Holothuria (Theelothuria) turriscelsa is a new record for the Indian Ocean. This study stresses the importance...
18 citations
TL;DR: The results of the nutritive parameters indicate that except for True Digestibility (which did not differ significantly between the two groups) all other indicators were significantly lower for the holothuria fed group.
Abstract: Two groups of rats were fed on diets with protein from a marine specie holothuria (Holothuria forskali) or casein (for the control group) during 16 days with the aim of assessing the nutritional value of the holothuria protein. Several serum lipid levels were also determined. The results of the nutritive parameters indicate that except for True Digestibility (which did not differ significantly between the two groups) all other indicators were significantly lower for the holothuria fed group. HDL-cholesterol level was significantly higher in the holothuria fed group, while triglyceride level was lower.
12 citations
Patent•
10 Apr 2000
TL;DR: In this paper, the authors proposed the general tonic nonspecific immunomodulating agent that is holothuria (sea cucumber; Cucumaria tricolor) hydrolyzate.
Abstract: FIELD: medicine. SUBSTANCE: invention proposes the general tonic nonspecific immunomodulating agent that is holothuria (sea cucumber; Cucumaria tricolor) hydrolyzate. EFFECT: broadened arsenal of agents. 5 cl, 2 tbl, 3 ex
3 citations