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Hot spot (veterinary medicine)
About: Hot spot (veterinary medicine) is a research topic. Over the lifetime, 1006 publications have been published within this topic receiving 16957 citations.
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1,121 citations
TL;DR: The picture that emerges is that protein-protein associations are optimized locally, with the clustered, networked, highly packed structurally conserved residues contributing dominantly and cooperatively to the stability of the complex.
492 citations
TL;DR: In this paper, the effects of hot spot geometry and surrounding temperature on the critical hot spot conditions are investigated, and these estimated temperatures, sizes, and times required for exothermic chemical reaction provide a means to evaluate proposed physical mechanisms of hot spots formation in accident scenarios involving impact (friction and shear) and shock compression of solid explosives.
Abstract: Chemical kinetic thermal decomposition models of pressed solid high explosives containing octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) and triaminotrinitrobenzene (TATB), which accurately calculate the times to explosion at various initial temperatures measured in the one-dimensional time to explosion (ODTX) test, are extended to higher temperatures to predict the critical temperatures, times to explosion, and dimensions of the impact- and shock-induced hot spots that are known to control the ignition of exothermic reaction in solid explosives. The effects of hot spot geometry and surrounding temperature on the critical hot spot conditions are investigated. Since hot spot temperatures and dimensions cannot be measured experimentally, these estimated temperatures, sizes, and times required for exothermic chemical reaction provide a means to evaluate proposed physical mechanisms of hot spot formation in accident scenarios involving impact (friction and shear) and shock compression of solid explosives.
394 citations
359 citations
TL;DR: In this article, a detailed analysis of the radio spectrum across the lobes of Cygnus A is presented in order to critically test the synchroton spectral aging theory, and the results are in good agreement with the jet model for powerful radio galaxies, involving particle acceleration at the hot spots and outflow into the radio lobes, with subsequent energy loss due to synchrotron radiation.
Abstract: A detailed analysis of the radio spectrum across the lobes of Cygnus A is presented in order to critically test the synchroton spectral aging theory. The results are in good agreement with the jet model for powerful radio galaxies, involving particle acceleration at the hot spots and outflow into the radio lobes, with subsequent energy loss due to synchrotron radiation. The hot spot spectra are well represented by a spectral aging model involving continuous injection of relativistic particles. Both hot spots have spectral break frequencies around 10 GHz. An injection index of 0.5 is found for both hot spots, consistent with diffusive shock acceleration at a strong nonrelativistic shock in a Newtonian fluid. The LF hot spot emission spectrum falls below the injected power law. This effect is isolated to the hot spots, and is best explained by a low-energy cutoff in the particle distribution.
355 citations