Topic
Hydrazone
About: Hydrazone is a research topic. Over the lifetime, 4853 publications have been published within this topic receiving 65160 citations. The topic is also known as: hydrazone.
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TL;DR: A series of 6-(morpholinosulfonyl)quinoxalin-2(1H)-one based hydrazone, hydrazine, and pyrazole moieties were designed, synthesized, and evaluated for their in vitro antimicrobial activity.
29 citations
TL;DR: An efficient rhodium-catalyzed oxidative coupling reaction has been developed that gives high yields of multisubstituted isoquinolines from easily accessible aryl hydrazones and internal alkynes.
Abstract: An efficient rhodium-catalyzed oxidative coupling reaction has been developed that gives high yields of multisubstituted isoquinolines from easily accessible aryl hydrazones and internal alkynes. Indenone hydrazone can also be synthesized in high yield from the corresponding benzaldehyde hydrazone by using this approach.
29 citations
Journal Article•
TL;DR: In this article, the nucleophilic addition of 2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one (1) to chalcone (2) was described.
Abstract: Pyrazolone derivative 3 was prepared by the nucleophilic addition of 2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one (1) to chalcone (2). Reaction of 3 with hydrazine hydrate, phenylhydrazine, hydroxylamine hydrochloride, p-chlorobenzaldehyde, acetyl chloride and phosphorus pentasulfide afforded the corresponding hydrazone, phenylhydrazone, oxime, arylidene, O-acetyl and dithio derivatives. Pyrazolone 1 was condensed also with cyclohexanone and aromatic aldehydes; the behaviour of the obtained arylidene derivatives towards hydrazines, cyclohexanone, malononitrile and urea was also investigated. Some of the new compounds showed antimicrobial and antifungal activities.
29 citations
29 citations