Topic
Hydrazone
About: Hydrazone is a research topic. Over the lifetime, 4853 publications have been published within this topic receiving 65160 citations. The topic is also known as: hydrazone.
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TL;DR: Glyoxal bishydrazones 1 and pyridyl-hydrazone 2b were prepared and examined as a ligand for the Mizoroki−Heck cross-coupling reaction of aryl halides and olefin this article.
Abstract: Glyoxal bishydrazones 1 and pyridyl-hydrazone 2b were prepared and examined as a ligand for the Mizoroki−Heck cross-coupling reaction of aryl halides and olefin. We found that PdCl2(MeCN)2/hydrazone ligand 1e was a phosphine-free efficient catalyst system for a variety of substrates to produce the Mizoroki−Heck coupling products in good yields.
111 citations
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TL;DR: Molecular modeling has provided insight into the structural basis for the anti-metallo-β-lactamase activity exhibited by this family of N-arylsulfonyl hydrazones.
Abstract: Members of a family of N-arylsulfonyl hydrazones have been identified as novel inhibitors of IMP-1, a metallo-β-lactamase of increasing prevalence. Structure-activity relationship studies have indicated a requirement for bulky aromatic substituents on each side of the sulfonyl hydrazone backbone for these compounds to serve as efficient inhibitors of IMP-1. Molecular modeling has provided insight into the structural basis for the anti-metallo-β-lactamase activity exhibited by this class of compounds.
107 citations
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TL;DR: The use of hemilabile pyridine-hydrazone N,N-ligands allows the highly selective Ir-catalyzed ortho,ortho'-directed diborylation of aromatic N, N-dimethylhydrazones in near-quantitative yields.
Abstract: The use of hemilabile pyridine–hydrazone N,N-ligands allows the highly selective Ir-catalyzed ortho,ortho′-directed diborylation of aromatic N,N-dimethylhydrazones in near-quantitative yields. One-pot sequential Suzuki–Miyaura cross-coupling with different aryl bromides provides a short entry to unsymmetrically substituted 2,6-diarylbenzaldehyde derivatives.
107 citations
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105 citations
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TL;DR: An experimental investigation on the effects of hydrazine treatment on graphene oxide via a reaction-model approach using small conjugated aromatic compounds containing various oxygen functional groups to mimic the structure of graphene oxide.
105 citations