Topic
Hydrogen peroxide
About: Hydrogen peroxide is a research topic. Over the lifetime, 42583 publications have been published within this topic receiving 1043732 citations. The topic is also known as: H2O2 & dioxidane.
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TL;DR: A new amperometric biosensor for hydrogen peroxide was developed based on cross-linking horseradish peroxidase by glutaraldehyde with multiwall carbon nanotubes/chitosan (MWNTs) composite film coated on a glassy carbon electrode that had good repeatability and stability for the determination of H(2)O(2).
232 citations
TL;DR: Observations suggest that H2O2 may act as a "second messenger" for the observed effects of insulin and suggest that insulin stimulation of intracellular H 2O2 production is linked to glucose metabolism.
232 citations
TL;DR: It is observed that two iron chelators, deferoxamine and hydroxybenzyl ethylenediamine (HBED), both inhibited spontaneous and accelerated apoptosis, suggesting that HO may mediate neutrophil apoptosis.
232 citations
TL;DR: This review discusses recent advances establishing a critical role of H2O2 in the development of vascular disease, in particular, atherosclerosis, and mechanisms whereby vascular NAD(P)H oxidase-derived H 2O2 amplifies its own production.
Abstract: Excessive production of reactive oxygen species in the vasculature contributes to cardiovascular pathogenesis. Among biologically relevant and abundant reactive oxygen species, superoxide (O2·−) an...
232 citations
TL;DR: The discovery of the enzyme superoxide dismutase that catalyzed the production of hydrogen peroxide from superoxide anion defined the new field of oxygen metabolism in biologic systems and a potential role of oxidation/reduction reactions in both physiologic and pathologic conditions.
232 citations