Topic
Hydroxysteroid dehydrogenase
About: Hydroxysteroid dehydrogenase is a research topic. Over the lifetime, 1087 publications have been published within this topic receiving 28468 citations. The topic is also known as: hydroxysteroid dehydrogenase.
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Journal Article•
2 citations
TL;DR: Contrasting patterns of activity between liver and steroid producing endocrine tissues is further evidence for the specificity of these techniques in the study of dehydrogenase distribution.
Abstract: In these experiments, a considerable range of hydroxysteroid dehydrogenases were demonstrated in vertebrate hepatic tissue; 3α, 3β, 6β, 11β, 16α, 16β, 17β and 20β were consistently present.
2 citations
TL;DR: Studies of Michaelis constants of 20-alpha-HSD indicate that this monoclonal antibody increases the Km for 20- alpha-dihydroprogesterone and decreases the Vmax.
2 citations
Patent•
27 May 2011
TL;DR: In this paper, 12 α-hydroxysteroid dehydrogenases, nucleic acid sequences coding for the same, expression cassettes and vectors, recombinant microorganisms containing the corresponding coding nucleic acids sequences, a method for producing said 12α-hydroxsteroid de-hydrogenase, a mechanism for enzymatic oxidation of 12 α -hydroxyl-steroid using said enzyme, and a method of 12-ketosteroid reduction of 12 -ketosteroids using said enzymes.
Abstract: The invention relates to 12 α-hydroxysteroid dehydrogenases, nucleic acid sequences coding for the same, expression cassettes and vectors, recombinant microorganisms containing the corresponding coding nucleic acid sequences, a method for producing said 12 α-hydroxysteroid dehydrogenases, a method for enzymatic oxidation of 12 α-hydroxysteroids using said enzyme, a method for enzymatic reduction of 12-ketosteroids using said enzyme, a method for qualitative or quantitative determination of 12-ketosteroids and/or 12α-hydroxysteroids using said 12α-hydroxysteroid dehydrogenases and a method for production of ursodesoxycholic acid, comprising the enzyme-catalyzed cholic acid oxidation using said 12 α-hydroxysteroid dehydrogenases.
2 citations