Showing papers on "Imaging technology published in 2007"
TL;DR: Magnetic resonance imaging and contrast enhanced ultrasonography are invaluable in problem solving for characterization indeterminate lesions, while contrast enhanced intra-operative ultrasound (CE-IOUS) may be the new gold standard staging tool prior to liver resection.
Abstract: Rapid advances in imaging technology have improved the detection, characterization and staging of colorectal liver metastases. Multi-modality imaging approach is usually the more useful in staging colorectal liver metastases. Multi-detector computed tomography (MDCT) remains the main imaging modality for preoperative planning, lesion detection and tumour surveillance. Magnetic resonance imaging (MRI) and contrast enhanced ultrasonography (US) are invaluable in problem solving for characterization indeterminate lesions, while contrast enhanced intra-operative ultrasound (CE-IOUS) may be the new gold standard staging tool prior to liver resection. Ultimately, the imaging strategy has to be tailored to the clinical situation to obtain the most relevant information for optimal use of available imaging resources.
56 citations
TL;DR: Molecular imaging is facilitating the development of molecular therapies and gene therapy, because molecular imaging makes it possible to noninvasively track and monitor targeted molecular therapies.
Abstract: Chronic musculoskeletal diseases such as arthritis, malignancy, and chronic injury and/or inflammation, all of which may produce chronic musculoskeletal pain, often pose challenges for current clinical imaging methods. The ability to distinguish an acute flare from chronic changes in rheumatoid arthritis, to survey early articular cartilage breakdown, to distinguish sarcomatous recurrence from posttherapeutic inflammation, and to directly identify generators of chronic pain are a few examples of current diagnostic limitations. There is hope that a growing field known as molecular imaging will provide solutions to these diagnostic puzzles. These techniques aim to depict, noninvasively, specific abnormal cellular, molecular, and physiologic events associated with these and other diseases. For example, the presence and mobilization of specific cell populations can be monitored with molecular imaging. Cellular metabolism, stress, and apoptosis can also be followed. Furthermore, disease-specific molecules can be targeted, and particular gene-related events can be assayed in living subjects. Relatively recent molecular and cellular imaging protocols confirm important advances in imaging technology, engineering, chemistry, molecular biology, and genetics that have coalesced into a multidisciplinary and multimodality effort. Molecular probes are currently being developed not only for radionuclide-based techniques but also for magnetic resonance (MR) imaging, MR spectroscopy, ultrasonography, and the emerging field of optical imaging. Furthermore, molecular imaging is facilitating the development of molecular therapies and gene therapy, because molecular imaging makes it possible to noninvasively track and monitor targeted molecular therapies. Implementation of molecular imaging procedures will be essential to a clinical imaging practice. With this in mind, the goal of the following discussion is to promote a better understanding of how such procedures may help address specific musculoskeletal issues, both now and in the years ahead.
51 citations
TL;DR: Despite the advances in anterior chamber imaging technology, there is still the need for a clinical, high-resolution, true anatomical, noninvasive technique to image behind the peripheral iris.
Abstract: PURPOSE OF REVIEW: Imaging of the crystalline lens and intraocular lens is becoming increasingly more important to optimize the refractive outcome of cataract surgery, to detect and manage complications and to ascertain advanced intraocular lens performance. This review examines recent advances in anterior segment imaging. RECENT FINDINGS: The main techniques used for imaging the anterior segment are slit-lamp biomicroscopy, ultrasound biomicroscopy, scheimpflug imaging, phakometry, optical coherence tomography and magnetic resonance imaging. They have principally been applied to the assessment of intraocular lens centration, tilt, position relative to the iris and movement with ciliary body contraction. SUMMARY: Despite the advances in anterior chamber imaging technology, there is still the need for a clinical, high-resolution, true anatomical, noninvasive technique to image behind the peripheral iris. © 2007 Lippincott Williams & Wilkins, Inc.
48 citations
TL;DR: This project developed evidence-based diagnostic imaging practice guidelines for musculoskeletal complaints for use by doctors of chiropractic and other primary health care professionals to help avoid unnecessary radiographs, increase examination precision, and decrease health care costs without compromising the quality of care.
42 citations
TL;DR: In routine practice, imaging information obtained with C-arm CT provides a subjective level of confidence factor to the operator that has not yet been quantified, and this may translate into a reduction in the utilization of iodinated contrast used by the operator, as well as a decrease in the radiation dose.
35 citations
01 Jan 2007
23 citations
22 Oct 2007
TL;DR: This work presents a novel tele-ultrasound approach designed to realize that potential by connecting a remote technician to a radiologist by using custom software and a satellite Internet connection.
Abstract: Ultrasound has great potential as an imaging technology in resource-limited environments. We present a novel tele-ultrasound approach designed to realize that potential by connecting a remote technician to a radiologist. Our preliminary system, based on open-source software and commercial off-the-shelf hardware, uses custom software and a satellite Internet connection to create this link. We also present the results of testing this system in both laboratory and real-world environments.
20 citations
Patent•
02 Mar 2007
TL;DR: In this article, the authors present a computer-based review and quality assurance system and method for physicians who use portable imaging technology to diagnose and treat patients at a point of care, which facilitates the credentialing of physicians, provides on-going quality assurance (QA), and integrates medical imaging equipment with software that runs over a network.
Abstract: The present invention is a computer-based review and quality assurance system and method for physicians who use portable imaging technology to diagnose and treat patients at a point of care. The system and method facilitates the credentialing of physicians, provides on-going quality assurance (QA), and integrates medical imaging equipment with software that runs over a network. Such credentialing assists medical institutions by identifying physicians who effectively use and diagnose patients with the imaging equipment.
19 citations
TL;DR: In this paper, a 1.75D 1280-channel ultrasound array with a center frequency of 5MHz and 80% bandwidth was designed and tested for co-registered 3D ultrasound and photo-acoustic imaging.
Abstract: Photoacoustic imaging is a promising non-invasive imaging technology due to its ability to combine the enhanced contrast of optical absorption with the spatial resolution of acoustic imaging. Co-registered three-dimensional (3-D) ultrasound and photoacoustic imaging takes advantage of both modalities to allow visualization of tissue structures within a volume using simultaneous structural and functional information. 1.75D acoustic arrays are well-suited for this application due to their ability to scan in 3-D volumes rapidly and accurately while maintaining a reasonable system complexity and cost. We have designed, fabricated, and tested a 1.75D 1280-ch ultrasound system for co-registered 3-D ultrasound and photoacoustic imaging. The system features a 1.75D 1280-channel ultrasound array with a center frequency of 5MHz and 80% bandwidth. The electronics includes 1280 high-voltage pulsers, 40 32-to-1 multiplexers, amplification circuitry, and a 40-channel data acquisition circuit. The system is able to drive the entire array simultaneously, and each array element independently, to scan a 3-D volume within +/- 40 degrees in azimuth direction and +/- 10 degrees in elevation respectively. System performance including axial and lateral resolution has been characterized and compared with simulations. Co-registered 3-D ultrasound and photoacoustic imaging has been successfully performed on phantoms with different geometries and contrast.
15 citations
TL;DR: This work discusses landmarks in neuroimaging in historical context, with emphasis on the particularly rapid development of imaging technology during the past 30 to 40 years, including the most recent emerging technologies.
Abstract: The history of the development of cerebral imaging is a complex combination of the forces of innovation at both the individual and industrial levels. Principal paradigms of neuroimaging shifted as a result of technological breakthroughs, beginning with the discovery of x-rays and continuing with the development of computerized imaging to the latest imaging paradigm, nuclear magnetic resonance imaging. We discuss these landmarks in neuroimaging in historical context, with emphasis on the particularly rapid development of imaging technology during the past 30 to 40 years, including the most recent emerging technologies.
15 citations
TL;DR: This paper synthesizes discussions of opportunities for research and development in four areas of imaging into a strategy for future research directions in biomedical imaging.
Abstract: The Fourth Biomedical Imaging Research Opportunities Workshop (BIROW IV) was held on February 24–25, 2006, in North Bethesda, MD. The workshop focused on opportunities for research and development in four areas of imaging:imaging of rodent models; imaging in drug development; imaging of chronic metabolic disease: diabetes; and image guided intervention in the fourth dimension-time. These topics were examined by four keynote speakers in plenary sessions and then discussed in breakout sessions devoted to identifying research opportunities and challenges in the individual topics. This paper synthesizes these discussions into a strategy for future research directions in biomedical imaging.
18 Jun 2007
TL;DR: An array imaging system, dubbed PERIODIC, is presented, capable of exploiting diversities, including subpixel displacement, phase, polarization, and wavelength, to produce superresolution images.
Abstract: An array imaging system, dubbed PERIODIC, is presented, capable of exploiting diversities, including subpixel displacement, phase, polarization, and wavelength, to produce superresolution images. The hardware system and software interface described, and sample results are shown.
01 Oct 2007
TL;DR: This work is developing a dual imaging system that will acquire PET and TRUS data during the same patient imaging session and accurately co-register the images, and is applicable to all PET-ultrasound imaging applications.
Abstract: Multi-modality imaging has an increasing role in the diagnosis and treatment of a large number of diseases, particularly if both functional and anatomical information are acquired and accurately co-registered. Although PET-CT has recently revolutionized the role of imaging for many kinds of cancer, ultrasound is the preferred imaging technology for many diseases such as prostate cancer. Transrectal ultrasound (TRUS) is an integral part of diagnosis and treatment for prostate cancer, so we are developing a dual imaging system that will acquire PET and TRUS data during the same patient imaging session and accurately co-register the images. In order to validate our methods prior to patient imaging, we will use a novel custom PET-TRUS prostate phantom. We present our initial PET- ultrasound phantom development, including PET and ultrasound images of a simple phantom, as well as discuss of our future phantom construction plans. We will use agar-gelatin tissue mimicking materials mixed with radioactive water solutions. Although we are currently focused on prostate imaging, this phantom development is applicable to all PET-ultrasound imaging applications. In addition, we discuss how to make a PET-ultrasound phantom also MRI and/or CT compatible.
TL;DR: A computational sensor design for high-resolution wide-angle imaging is presented by multiplexing multiple sub-fields-of-view onto a single image sensor using feature-specific imaging techniques.
Abstract: We present a computational sensor design for high-resolution wide-angle imaging by multiplexing multiple sub-fields-of-view onto a single image sensor using feature-specific imaging techniques.
Patent•
14 Nov 2007
TL;DR: In this article, a cargo security inspection method based on helical scan imaging technology, including the application of dual-energy-ray source, turntable, data acquisition modules and main control computer and data processing Cargo security inspection system, is presented.
Abstract: This invention involves radiation detection technology fields, particularly a cargo security inspection method based on helical scan imaging technology, including the application of dual-energy-ray source, turntable, data acquisition modules and main control computer and data processing cargo security inspection system. The method includes: A. rapid spiral scan of the subject, reconstruction the image of physical parameters of the subject; B. judging if image reconstruction has suspects region, if it exists, the implementation of steps C; Otherwise, the end of this process; C. computer tomography the suspects region, reconstruction suspects region sectional images, and according to the redevelopment of the subject sectional images of conducting security checks. The invention can cut scanning time, and save the security checks time on goods, to achieve fast and accurate inspection. In addition, this invention is low cost, and very helpful to the promotion and application.
26 Aug 2007
TL;DR: Recent advances in OCT technology and applications are described which enable ultrahigh resolution imaging on the micron scale using broadband femtosecond lasers and enable three dimensional imaging and visualization similar to that in MR imaging.
Abstract: Summary form only given. Optical coherence tomography (OCT) is an emerging imaging technology which can generate high resolution, cross-sectional images of materials and biological tissues. OCT is analogous to ultrasound imaging, except that it measures the echo time delay of backscattered or backreflected light. Recently there have been dramatic advances in OCT which enable ultrahigh resolution imaging on the micron scale using broadband femtosecond lasers. New detection techniques have been developed which measure echo time delays of light in the Fourier domain, enabling 10 to 100 times increases in imaging sensitivity or speed. These advances enable three dimensional imaging and visualization similar to that in MR imaging. OCT is rapidly becoming a standard clinical diagnostic in ophthalmology, where it enables imaging and measurement of retinal pathology with unprecedented resolutions. OCT is also being developed for many other applications ranging from cancer detection in endoscopy, to intravascular imaging in cardiology. This presentation will describe recent advances in OCT technology and applications.
Journal Article•
TL;DR: The Electrical Impedance Tomography (EIT) is divided into the static state EIT and dynamic EIT as mentioned in this paper, where the latter is the relatively value of the distributing of electrical impedance relatively value.
Abstract: The Electrical Impedance Tomography(EIT)is divided into the static state EIT(The imaging target is the absolute value of the distributing of Electrical Impedance)and dynamic EIT(The imaging target is the relatively value of the distributing of Electrical Impedance relatively value)It's comparatively popular imaging technology in the study of biomedicine engineering at home and abroad in recent yearsCompared to the present imaging technique of X-ray,computer section scanning (CT),MRI and ultrasonic,this new technique has not only the anatomy information but the character of functional imagingIt has a beautiful applied foreground in clinic application for its characters such as its character of non-invasion,simple,low cost and easy useBy using math,physics,and its new application at home and abroad,this paper gives an instruction of the math computation of the(ETI),the prindple of physics,as well as the basic principle of EIT and its clinic application
TL;DR: The physical nature and characteristics of the image ranging technology are examined, the potential for further system characterization and calibration to compensate for the range determination and other errors are discussed, which could possibly lead to three-dimensional measurement precision approaching that of photogrammetry.
Abstract: Solid-state full-field range imaging technology, capable of determining the distance to objects in a scene simultaneously for every pixel in an image, has recently achieved sub-millimeter distance measurement precision. With this level of precision, it is becoming practical to use this technology for high precision three-dimensional metrology applications. Compared to photogrammetry, range imaging has the advantages of requiring only one viewing angle, a relatively short measurement time, and simplistic fast data processing. In this paper we fist review the range imaging technology, then describe an experiment comparing both photogrammetric and range imaging measurements of a calibration block with attached retro-reflective targets. The results show that the range imaging approach exhibits errors of approximately 0.5 mm in-plane and almost 5 mm out-of-plane; however, these errors appear to be mostly systematic. We then proceed to examine the physical nature and characteristics of the image ranging technology and discuss the possible causes of these systematic errors. Also discussed is the potential for further system characterization and calibration to compensate for the range determination and other errors, which could possibly lead to three-dimensional measurement precision approaching that of photogrammetry.
TL;DR: Making films of atomic-scale processes as they happen makes huge demands on any imaging system, so one approach combines the advantages of pulsed laser harmonics and computerized image reconstruction.
Abstract: Making films of atomic-scale processes as they happen makes huge demands on any imaging system. One approach combines the advantages of pulsed laser harmonics and computerized image reconstruction.
Journal Article•
TL;DR: The new grading scheme can be used reliably to categorize the strength of scientific knowledge provided by individual studies of vascular imaging, and could assist clinicians and researchers in determining appropriate clinical applications of newly reported technical advances.
Abstract: Imaging of head and neck vasculature continues to improve with the application of new technology. To judge the value of new technologies reported in the literature, it is imperative to develop objective standards optimized against bias and favoring statistical power and clinical relevance. A review of the existing literature identified the following items as lending scientific value to a report on imaging technology: prospective design, comparison with an accepted modality, unbiased patient selection, standardized image acquisition, blinded interpretation, and measurement of reliability. These were incorporated into a new grading scheme. Two physicians tested the new scheme and an established scheme to grade reports published in the medical literature. Inter-observer reliability for both methods was calculated using the kappa coefficient. A total of 22 reports evalualiiig imaging modalities for cervical internal carotid artery stenosis were identified from a literature search and graded by both schemes. Agreement between the two physicians in grading the level of scientific evidence using the new scheme was excellent (kappa coefficient: 0.93, p<0.0001). Agreement using the established scheme was less rigorous (kappa coefficient: 0.39, p<0.0001). The weighted kappa coefficients were 0.95 and 0.38 for the new and established schemes, respectively. Overall agreement was higher for the newer scheme (95% versus (61%). The new grading scheme can be used reliably to categorize the strength of scientific knowledge provided by individual studies of vascular imaging. The new method could assist clinicians and researchers in determining appropriate clinical applications of newly reported technical advances.
01 Jan 2007
TL;DR: MRI is a very versatile imaging modality which can be used to acquire several different types of images, and some examples include anatomical images, images showing local b ...
Abstract: Magnetic resonance imaging (MRI) is a very versatile imaging modality which can be used to acquire several different types of images. Some examples include anatomical images, images showing local b ...
01 Jan 2007
TL;DR: An image simulation chain has been devised from which various doses and other generic system parameters can be simulated, and preliminary results show that the method provides a good quality initial simulation of real CDMAM images.
Abstract: With the recent developments in digital mammography, it is becoming increasingly important to be able to compare different technologies used for detecting breast cancer. By using simulation tools, it may be made possible to not only compare the images generated by different technologies but also the effect of dose levels and other imaging parameters within the same system. Images of a test phantom (CDMAM) have been simulated in this study as a proof of principle. An image simulation chain has been devised from which various doses and other generic system parameters can be simulated. Preliminary results show that the method provides a good quality initial simulation of real CDMAM images.
Journal Article•
TL;DR: In this paper, a sort of IR imaging system consisting of micro-cantilever array and optical-readout device is presented, which discusses its imaging principle, influence factor.
Abstract: Uncool IR imaging technology, because of its low cost and high credibility, has attracted more and more attention. Recently a sort of IR imaging system consisting of micro-cantilever array and optical-readout device is presented. This paper discusses its imaging principle, influence factor. Finally, it indicates the way this kind of devices will follow.
TL;DR: The practice of electronic portal imaging review and verification in the treatment of breast cancer can be streamlined and achieved more efficiently because the Radiation Therapists consistently demonstrated their ability to review and verify the portal images, as equivalent to the Radiation Oncologist.
TL;DR: Better results can be obtained in the diagnosis of HCC, decision of treatment method and assessment of therapeutic response if more durable contrast agents are used with advanced US techniques.
01 Jan 2007
TL;DR: An overarching framework that allows us to interpret the information from an image and how quality can be extended to the judgement of the influence of imaging technology on the clinical management of patients, including the quality of life of the patient is described.
Abstract: In this paper we describe an overarching framework that allows us to interpret the information from an image. Starting with the imaging device, consideration will be given to the measurement of the quality of the raw data detected by the instrument. This uses Bayesian signal detection theory to combine the large area transfer characteristic, the modulation transfer function and the noise power spectrum in a single measure of quality.Then we will discuss how to assess the quality of the displayed image by measuring human performance directly. The most complete description of observer performance is provided by Receiver Operating Characteristic (ROC) analysis, which estimates all the combinations of sensitivity and specificity available from an imaging procedure. How subjective measures of image quality can be combined with the objective assessment of performance will be investigated. Finally, we will show how quality can be extended to the judgement of the influence of imaging technology on the clinical management of patients, including the quality of life of the patient.
15 May 2007
TL;DR: The design and evaluation of a novel easy to use, tissue viability imaging system (TiVi), based on the methods of diffuse reflectance spectroscopy and polarizationSpectroscopy, which is sensitive to red blood cells in the microcirculation is described.
Abstract: This paper describes the design and evaluation of a novel easy to use, tissue viability imaging system (TiVi). The system is based on the methods of diffuse reflectance spectroscopy and polarization spectroscopy. The technique has been developed as an alternative to current imaging technology in the area of microcirculation imaging, most notably optical coherence tomography (OCT) and laser Doppler perfusion imaging (LDPI). The system is based on standard digital camera technology, and is sensitive to red blood cells (RBCs) in the microcirculation. Lack of clinical acceptance of both OCT and LDPI fuels the need for an objective, simple, reproducible and portable imaging method that can provide accurate measurements related to stimulus vasoactivity in the microvasculature. The limitations of these technologies are discussed in this paper. Uses of the Tissue Viability system include skin care products, drug development, and assessment spatial and temporal aspects of vasodilation (erythema) and vasoconstriction (blanching).
Journal Article•
TL;DR: The novel combined X-ray image intensifier has a very high cost effectiveness and the satisfied imaging performance, and moreover, the quality disparity between the novel combined one and the imported medical one is being shortened.
Abstract: By combining X-ray imaging technology and low light level imaging technology, the authors' research group designed the novel combined X-ray image intensifier. Different from the imported conventional one, it is an X-ray screen lens coupled with a brightness intensifier, and is a non-vacuum device. In this paper, the novel combined X-ray image intensifier is described in terms of its structure, imaging principle and imaging performance, and the comparisons of the structure, imaging principle and imaging performance between the novel combined one and the conventional one are given in detail. It is clear that the conventional medical tube is a little better than the novel combined one in imaging performance, whereas the novel combined one has a very high cost effectiveness and the satisfied imaging performance, and moreover, the quality disparity between the novel combined one and the imported medical one is being shortened. The novel combined one meets the X-ray imaging standard in many science and research fields and is convenient to be accepted by the usual users and has wide application fields such as industrial detection, nondestructive test and airport security check.
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TL;DR: One of the main driving forces for the current development in CT is for applications in cardiology, and with multislice detectors, spiral acquisition, and subsecond rotation times, CT continues to develop and to play a major role in clinical imaging, in particular for the assessment of cardiovascular disease.
Abstract: The recent development of combined positron emission tomography/computed tomography (PET/CT) instrumentation is an important evolution in imaging technology. Since the introduction of the first prototype CT scanner in the early 1970s, tomographic imaging has made significant contributions to the diagnosis and staging of disease. Rapid commercial development followed the introduction of the first CT scanner in 1972, and within 3 years of its appearance more than 12 companies were marketing, or intending to market, CT scanners; about half that number actually market CT scanners today. With the introduction of magnetic resonance imaging (MRI) in the early 1980s, CT was, at that time, predicted to last another 5 years at most before being replaced by MRI for anatomical imaging. Obviously, this did not happen, and today, with multislice detectors, spiral acquisition, and subsecond rotation times, CT continues to develop and to play a major role in clinical imaging, in particular for the assessment of cardiovascular disease. Indeed, one of the main driving forces for the current development in CT is for applications in cardiology.