Imaging technology

About: Imaging technology is a research topic. Over the lifetime, 1450 publications have been published within this topic receiving 26186 citations.

Digital X-ray imaging

Abstract: Digital radiography is progressively replacing conventional (film-based) radiographic techniques promising consistently high levels of image quality, more effective use of radiation and more efficient work practices. At the same time its introduction poses new challenges to those physical scientists who design radiological imaging systems and those who provide scientific/technical support to a clinical radiology service Scientific aspects of those digital X-ray imaging systems which are proving most successful are described. Physical measurement techniques developed to evaluate the imaging performance and radiation dose efficiency of clinical digital radiography systems are outlined. Directions in which digital X-ray imaging technology may evolve in the 1990s are discussed.

Four-dimensional ultrasound in prenatal diagnosis: leading edge in imaging technology

Abstract: Since the introduction of the three-dimensional imaging technique, significant improvements have been undertaken. With the development of computer technology, calculation times become shorter and the software becomes more sophisticated. In the initial years, three-dimensional ultrasound allowed the production of only still volumes. Thus, scans only represented one single moment within the total examination. Serial re-scanning is one of the newest developments in three-dimensional ultrasound. In the volume-rendering mode, still imaging now may be replaced by three-dimensional ultrasound ‘movies’. This technique may also be called four-dimensional ultrasound' or live three-dimensional ultrasound'. However, a frame rate of about 10 frames per second would be necessary to bring this technique to ‘real-time’ mode. Possible applications in prenatal diagnosis are examinations of the fetal extremities, fetal face and may be fetal behavior. Among the many advantages of four-dimensional ultrasound, improvem...

Noninvasive Imaging of Tumor Burden and Molecular Pathways in Mouse Models of Cancer

Abstract: Imaging plays a central role in the diagnosis of cancer and the evaluation of therapeutic efficacy in patients with cancer. Because macroscopic imaging is noninvasive and quantitative, the development of specialized instruments for small animals has spurred increasing utilization in preclinical cancer studies. Some small-animal imaging devices are miniaturized derivatives of clinical imaging modalities, including computed tomography, magnetic resonance imaging, positron-emission tomography, single-photon emission computed tomography, and ultrasonography. Optical imaging, including bioluminescence imaging and fluorescence imaging, has evolved from microscopic cellular imaging technologies. Here, we review how current imaging modalities are enabling high-resolution structural imaging with micrometer-scale spatial resolution, thus allowing for the quantification of tumor burden in genetically engineered and orthotopic models of cancer, where tumors develop within organs not typically accessible to measurements with calipers. Beyond measuring tumor size, imaging is increasingly being used to assess the activity of molecular pathways within tumors and to reveal the pharmacodynamic efficacy of targeted therapies. Each imaging technology has particular strengths and limitations, and we discuss how studies should be carefully designed to match the imaging approach to the primary experimental question.

Marker localization using intensity-based registration of imaging modalities

Abstract: Provided are methods and systems for registering image data from two imaging modalities, to produce an image having features from both imaging technologies. In particular, the methods and systems relate to intensity-based registration of the image data. The imaging modalities may be, for example, ultrasound and x-ray, magnetic resonance imaging, or a pre-operative plan.