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Indole alkaloid

About: Indole alkaloid is a research topic. Over the lifetime, 868 publications have been published within this topic receiving 15401 citations. The topic is also known as: indole alkaloids.


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Book ChapterDOI
TL;DR: The chapter describes many successful results concerning monoterpenoid indole alkaloid syntheses performed in recent decades by utilizing a biomimetic reaction in a synthetically crucial step.
Abstract: Publisher Summary The chapter discusses monoterpenoid indole alkaloid syntheses utilizing biomimetic reactions and reviews the significant accomplishments concerning the biomimetic synthesis of secologanin-derived monoterpenoid indole alkaloids that have been reported in the past 10–15 years This chapter consists of five areas of research in the field: (1) biomimetic syntheses of Corynanthe-related alkaloids from secologanin, strictosidine, and their analogues, (2) syntheses of Aspidosperma and Iboga alkaloids via secodine or dehydrosecodine intermediates, (3) biomimetic skeletal rearrangement and fragmentation, (4) biomimetic syntheses in the Sarpagine family, and ( 5 ) biomimetic bisindole alkaloid syntheses The chapter describes many successful results concerning monoterpenoid indole alkaloid syntheses performed in recent decades by utilizing a biomimetic reaction in a synthetically crucial step Adopting this biomimetic strategy, a number of structurally complex and/or unusual alkaloids are synthesized efficiently in a regio- and stereoselective manner The biosynthesis by chemical means has led to the discovery of new synthetic methodology and reactions In some cases, biogenetically patterned synthesis supported (or provided proof of) the postulated biosynthetic pathway

7 citations

Journal ArticleDOI
TL;DR: CIMiciduphytine, a new dimeric indole alkaloid from Haplophyton cimicidum (Apocynaceae) has been assigned the aspidosperma-canthinone bisindole structure.
Abstract: Cimiciduphytine, a new dimeric indole alkaloid from Haplophyton cimicidum (Apocynaceae) has been assigned the aspidosperma-canthinone bisindole structure

7 citations

Journal ArticleDOI
TL;DR: Reflexine, a new indole alkaloid, has been isolated from the leaves of Rauwolfia reflexa Teijsm.
Abstract: Reflexine, a new indole alkaloid, has been isolated from the leaves ofRauwolfia reflexa Teijsm. and Binn. From spectral studies, chemical reactions and correlation with seredamine, reflexine is shown to be its C-17 epimer (IV).

7 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202329
202254
202133
202029
201923
201828