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Indole alkaloid

About: Indole alkaloid is a research topic. Over the lifetime, 868 publications have been published within this topic receiving 15401 citations. The topic is also known as: indole alkaloids.


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Journal ArticleDOI
TL;DR: A monoterpene indole alkaloid, naucleamide F (1), has been isolated from the bark and wood of Nauclea latifolia, and the structure and stereochemistry were elucidated on the basis of spectral data.
Abstract: A new monoterpene indole alkaloid, naucleamide F (1), has been isolated from the bark and wood of Nauclea latifolia, and the structure and stereochemistry were elucidated on the basis of the spectral data. Naucleamide F (1) is a new monoterpene indole alkaloid consisting of a tetrahydro-β-carboline ring fused to a pyridone ring, and a 1,3,5-trioxepane ring fused to a dihydropyran ring and a glucose unit.

5 citations

Journal ArticleDOI
TL;DR: To produce economically important indole alkaloids by cell culture, protoclones ofCatharanthus roseus are selected for high yields of catharanthine and ajmalicine and qualitatively confirmed by LC-MS.
Abstract: To produce economically important indole alkaloids by cell culture, we have selected protoclones ofCatharanthus roseus for high yields of catharanthine and ajmalicine. Protoplasts were enzymatically isolated from suspension-cultured cells. Protoclone VPC-10 produced catharanthine at 5.9 μg/g fresh wt of cells after 10 days of culture, although the original cell line did not produce it at a level detectable by HPLC. Under the same conditions, protoclone VPC-15 produced ajmalicine at 133.6 μg/g, which was about 3 times the productivity of the original cell line. In addition, the indole alkaloids were qualitatively confirmed by LC-MS.

5 citations

Journal ArticleDOI
TL;DR: A new indole alkaloid, hyderabadine, has been isolated from the leaves of Ervatamia coronaria to which structure 1 has been assigned as discussed by the authors.
Abstract: A new indole alkaloid, hyderabadine, has been isolated from the leaves of Ervatamia coronaria to which structure 1 has been assigned.

5 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202329
202254
202133
202029
201923
201828