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Indole alkaloid

About: Indole alkaloid is a research topic. Over the lifetime, 868 publications have been published within this topic receiving 15401 citations. The topic is also known as: indole alkaloids.


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Patent
11 May 1990
TL;DR: In this paper, a tissue culture of tissues from a plant capable of producing the indole alkaloid in a culture medium containing fructose as a saccharide source was carried out.
Abstract: PURPOSE:To enable efficient obtaining of an indole alkaloid in a large amount by carrying out tissue culture of tissues from a plant capable of producing the indole alkaloid in a culture medium containing fructose as a saccharide source CONSTITUTION:A cultivar Cathranthus roseus var LittleBrightEye, etc, of a plant of the genus Lochnera is bedded on a solid MurashigeSkoog culture medium containing agar and cultured at 10 to 35 degC for 7 to 30 days to provide calli On the other hand, 2 to 5wt% fructose is blended with 01muM to 100mM inorganic ingredient, such a s Ca, 001 to 10muM phytohormone, such as indoleacetic acids, 01 to 100mg/l each of vitamins, such as biotin or glycine, and amino acids and added to the MurashigeSkoog culture medium to afford a liquid culture medium for tissue culture The aforementioned calli are then inoculated into the abovementioned culture medium and cultured at 10 to 35 degC After completing the culturing calli are separated by a decantation method or filtration, etc, to afford calli, which are subsequently extracted and purified with methanol, etc, to produce an indole alkaloid, such as catharanthine

2 citations

Journal ArticleDOI
TL;DR: In this article , ten new indole alkaloids (1, 10, 11, 12, 14, 15, 16, 17, 19, 20, 21 and 21) were isolated from the stems and hooks of Uncaria rhynchophylla and their structure elucidation was based on extensive NMR studies, MS and ECD data.

2 citations

Journal ArticleDOI
TL;DR: A new indole alkaloid, arboflorine, possessing a novel pentacyclic carbon skeleton and incorporating a third nitrogen atom was obtained from the Malayan Kopsia arborea as discussed by the authors.
Abstract: A new indole alkaloid, arboflorine, possessing a novel pentacyclic carbon skeleton and incorporating a third nitrogen atom was obtained from the Malayan Kopsia arborea. The structure was established by spectroscopic analysis, and a possible biogenetic pathway from a preakuammicine-type precursor is presented.

2 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202329
202254
202133
202029
201923
201828