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Indole alkaloid
About: Indole alkaloid is a research topic. Over the lifetime, 868 publications have been published within this topic receiving 15401 citations. The topic is also known as: indole alkaloids.
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TL;DR: A hexacylic indole alkaloid, tronoharine, was obtained from the stem-bark extract of Tabernaemontana corymbosa and its structure elucidated by spectral analysis as discussed by the authors.
Abstract: A novel hexacylic indole alkaloid, tronoharine, was obtained from the stem-bark extract of Tabernaemontana corymbosa and its structure elucidated by spectral analysis.
TL;DR: In this article, the synthesis of aldehyde intermediates suitable for the preparation of indole alkaloids of the tacamine (1) type is described, and four possible aldehydes 4-7 were prepared from methyl 5-ethylnicotinate (8) in a few simple steps using a base-catalyzed epimerization as the final step.
Abstract: The synthesis of aldehyde intermediates suitable for the preparation of indole alkaloids of the tacamine (1) type is described. The four possible aldehydes 4–7 were prepared from methyl 5-ethylnicotinate (8) in a few simple steps using a base-catalyzed epimerization as the final step (Schemes 1 and 2). The key aldehyde 4, which is an analogue of the important vincamine intermediate 3 (‘Oppolzer's aldehyde’), was finally converted into the indole alkaloid (±)-apotacamine (21).
TL;DR: Aurantioclavine, isolated by Kozlovskii from Penicillium aurantiovirens, is a unique member of the 3,4 disubstituted indole alkaloids distinguished by an azepino[5,4,3-cd]indole as mentioned in this paper .
TL;DR: In this paper , the tetrakis monoterpene indole alkaloid alasmontamine A, with a molecular formula of C84H91N8O12, was calculated within the DFT framework.
Abstract: 1H and 13C NMR chemical shifts of the tetrakis monoterpene indole alkaloid alasmontamine A, with a molecular formula of C84H91N8O12, have been calculated within the DFT framework. Six minimum energy conformers of this alkaloid were identified, and three key configurations that contribute to its NMR shielding constants were established. Several ambiguities in the reported assignment of the NMR chemical shifts of alasmontamine A have been resolved.