Topic
Indole alkaloid
About: Indole alkaloid is a research topic. Over the lifetime, 868 publications have been published within this topic receiving 15401 citations. The topic is also known as: indole alkaloids.
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TL;DR: In this paper, four gelsedine-type oxindole alkaloids (1, 2, 3 and 4) were isolated from the leaves and branches of Gelsemium elegans.
31 citations
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30 citations
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TL;DR: The results strongly suggested that NO released from SNP triggered terpenoid indole alkaloid biosynthesis of C. roseus cells through a protein kinase-dependent signal pathway.
30 citations
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TL;DR: A new indole alkaloid, together with four known indole alkaloids, was isolated from the 95% EtOH extract of the traditional Chinese medicinal plant Isatis indigotica as mentioned in this paper.
Abstract: A new indole alkaloid 1, together with four known indole alkaloids 2–5, was isolated from the 95% EtOH extract of the traditional Chinese medicinal plant Isatis indigotica. Alkaloids 2–5 were found in the plant for the first time. Their structures were elucidated as 3-hydroxy-3-acetonitrile-4-hydroxy-2-indolone (1), 1-methoxy-3-indoleacetonitrile (2), 3-indoleacetic acid (3), 3-indolealdehyde (4), and 1-methoxy-3indolecarbaldehyde (5) on the basis of spectroscopic data. Their anti-HSV effects in vitro were evaluated by plaque reduction assay.
30 citations
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TL;DR: Three indole alkaloids and a new alkaloid, 5-hydroxy-3,6-oxidovoacangine, isolated from Voacanga africana were found to exhibit potent cannabinoid CB1 receptor antagonistic activity, the first example of CB1 antagonists derived from natural alkal steroids.
30 citations