scispace - formally typeset
Search or ask a question
Topic

Indole alkaloid

About: Indole alkaloid is a research topic. Over the lifetime, 868 publications have been published within this topic receiving 15401 citations. The topic is also known as: indole alkaloids.


Papers
More filters
Journal ArticleDOI
TL;DR: Two new oxindole alkaloids, rankiniridine (1 ) and humanteniridine(2 ), having a nitrogen-carbon linkage between a humantene-type monoterpenoid indole alkaloid and a monoterpene unit with an iridoid skeleton, were isolated from Gelsemium rankinii and Gelsemia elegans, respectively as mentioned in this paper.

18 citations

Journal ArticleDOI
TL;DR: This work describes a strategic approach for the synthesis of cyclohepta[b]indole structural scaffolds using a solvent-free Baylis-Hillman reaction of 2-bromobenzaldehydes and intramolecular Heck coupling reaction using Pd(OAc)2 as catalyst in the presence of benzyltrimethylammonium bromide under microwave condition.
Abstract: Ervatamine, silicine, methuenine, etc., are naturally occurring alkaloids that exhibit antimicrobial, anticancer, and anti-HIV activities. Indole fused with a seven-membered carbocyclic ring is a commonly observed structural feature among this series of bioactive compounds. This work describes a strategic approach for the synthesis of cyclohepta[b]indole structural scaffolds. The synthetic strategy consists of a solvent-free Baylis-Hillman reaction of 2-bromobenzaldehydes, followed by iodine-catalyzed C-alkylation of indole with the Baylis-Hillman adducts. Finally, intramolecular Heck coupling reaction using Pd(OAc)2 as catalyst in the presence of benzyltrimethylammonium bromide under microwave condition produced the desired cyclohepta[b]indole derivatives.

18 citations

Journal ArticleDOI
TL;DR: The ABC-rings of nodulisporic acid were found to contain the structural and stereochemical elements of the ABC-ring of the aldehyde as discussed by the authors, which is the most similar structure to ours.

18 citations

Journal ArticleDOI
TL;DR: Pamburus missionis root contained imperatorin and 7-hydroxy-8-(3′,7′-dimethyl octa-2′,6′-dien)ylcoumarin and a new natural product, 3-(3-methyl-1-oxo-2-butenyl) 1H indole.

17 citations


Network Information
Related Topics (5)
Absolute configuration
7.8K papers, 124.7K citations
90% related
Triterpene
4.1K papers, 81.1K citations
89% related
Glycoside
4.6K papers, 80.8K citations
88% related
Indole test
19.9K papers, 318K citations
88% related
Isoquinoline
5.8K papers, 68.6K citations
88% related
Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202329
202254
202133
202029
201923
201828