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Intracranial Lipoma

About: Intracranial Lipoma is a research topic. Over the lifetime, 147 publications have been published within this topic receiving 2394 citations.


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Journal ArticleDOI
TL;DR: Lipomas of the pineal region are rare and modern neuroimaging permits a straightforward diagnosis of the nature of intracranial lipoma in general and of these lipomas in particular.

15 citations

Journal ArticleDOI
TL;DR: It is concluded that surgery for CPA lipomas should be reserved for tumors that are truly symptomatic or if biopsy sampling is required for differential diagnosis, as was seen in this case.
Abstract: ed trigeminal neuralgia (TN). As seen in Fig. 1, magnetic resonance (MR) imaging of the cranium revealed a hyperintense mass lesion on both T1and T2-weighted images in the left cerebellopontine angle (CPA). A left suboccipital retrosigmoid approach disclosed a yellowish mass that encased the seventh and the eighth cranial nerves. The fifth cranial nerve was found to be displaced ventrally by the tumor. There were no vascular elements causing compression along the course of the trigeminal nerve. Approximately 40% of the tumor was removed but the seventh and the eighth cranial nerves were obviously traumatized. Postoperatively, the patient reported complete relief of TN but noted left-sided facial paralysis and deafness. Intracranial lipomas are uncommon; only 0.1% of brain lesions are fatty tumors.2 Of the 46 CPA lipomas reported, only seven cases have presented with TN.3 Lipomas usually occur at junctions between segments of the central nervous system, and these junctions represent sites of neural tube flexion as well as of redundant meninx primitiva.1 This finding supports the concept of lipoma formation as a result of abnormal persistence and maldifferentiation of the meninx. Surgery for CPA lipomas is quite controversial because of the difficulty of total removal of such a slow-growing lesion. Adherence to the adjacent cranial nerves is the major reason for increased postoperative morbidity, as was seen in our case.1,3 Malignant differentiation or rapid growth have never been reported.4 We conclude that surgery should be reserved for tumors that are truly symptomatic or if biopsy sampling is required for differential diagnosis.

15 citations

Journal ArticleDOI
TL;DR: Two cases of quadrigeminal plate cistern lipoma detected by CT scan, one of which produced impairment of vertical gaze, are reported.
Abstract: Two cases of quadrigeminal plate cistern lipoma detected by CT scan, one of which produced impairment of vertical gaze, are reported. The problems of diagnosis and therapy of intracranial lipomas are briefly discussed.

14 citations

Journal ArticleDOI
TL;DR: A stronger association of corpus callosum hypoplasia with posteriorly situated curvilinear lipomas is found and is in disagreement with previous studies, which suggested corpuscallosum anomalies were more often associated with anteriorly situated tubulonodular lipomas.
Abstract: Aim A pericallosal lipoma is a fat-containing lesion occurring in the interhemispheric fissure closely related to the corpus callosum, which is often abnormal. This is the most common location for an intracranial lipoma. In this study, we aim to report on the clinical and radiographic aspects of ten patients diagnosed with pericallosal lipomas. Material and methods A retrospective analysis of patients who presented to the neurology and neurosurgery outpatient clinics of Kayseri Training and Research Hospital between 2010 and 2014 revealed that 10 patients had the diagnosis of pericallosal lipoma. The clinical and magnetic resonance imaging data were obtained by reviewing their files. Results Ten patients with an average age of 35.8 years (11-80 years) were included in the study. The mean follow-up was 17 months (8-31 months). No neurological deficits related to the lesions were found during neurological examination in any of the patients. Four patients had tubulonodular lipomas while the other 6 presented with curvilinear lipomas. Four patients (40%) displayed a coexistent corpus callosum hypoplasia. In contrast to previous reports, 3 of these patients had a curvilinear lipoma while the remaining one had tubulonodular lipoma. Also, one of the patients displayed plaque lesions attributable to multiple sclerosis. During the follow-up period, no growth in the lipomas was recorded in any of the patients. No surgical intervention was performed as none of the patients displayed symptoms caused by the lipoma. Conclusion In this study, we found a stronger association of corpus callosum hypoplasia with posteriorly situated curvilinear lipomas. Our results are in disagreement with previous studies, which suggested corpus callosum anomalies were more often associated with anteriorly situated tubulonodular lipomas. Pericallosal lipomas are benign, self-limiting or slow-growing lesions that generally remain asymptomatic. These lesions occur in the midline and surround critical neurovascular structures. Therefore, surgical intervention should be avoided in asymptomatic cases.

14 citations

Journal ArticleDOI
15 Jul 1982-Cancer
TL;DR: A 74‐year‐old woman presented with a symptomatic posterior fossa mass which was successfully resected, marking the first case report of intracranial myelolipoma as well as the first reported successful surgical resection of this tumor in this location.
Abstract: A 74-year-old woman presented with a symptomatic posterior fossa mass which was successfully resected. Histologic examination revealed that the tumor was composed primarily of adipose and hematopoietic tissues warranting the diagnosis of myelolipoma. This represents the first case report of intracranial myelolipoma as well as the first reported successful surgical resection of this tumor in this location. A review of this subject indicates that the term myelolipoma denotes tumors with at least two different etiologies. The first represents metaplastic differentiation within a lipoma and the second appears to be a response of adrenal tissue to noxious stimuli.

13 citations

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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20214
20204
20193
20183
20174
20164